Natural History and Patterns of Treatment Change in Parkinson’s Disease: A Retrospective Chart Review

2019 ◽

Vol 46 (s1) ◽

pp. S45-S46

Author(s):

A Persad ◽

K Meguro

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Normal Pressure Hydrocephalus ◽

Chart Review ◽

Functional Decline ◽

Retrospective Chart Review ◽

Normal Pressure ◽

Careful Consideration ◽

The Other ◽

Extrapyramidal Signs

Background: Normal pressure hydrocephalus is a frequent cause of cognitive and functional impairment. Many symptoms are shared between Parkinson’s disease and normal pressure hydrocephalus. Only few studies examine extrapyramidal signs in NPH, and only one case report exists describing tremor improvement with shunting. Methods: We performed a retrospective chart review of our NPH database. We selected patients who had both NPH and question of Parkinsonism due to tremor. Results: Six patients with both NPH diagnosis and tremor were identified. Three patients were treated for Parkinson’s disease and followed by neurology. After shunting, all three improved and attempt was made to wean medications, which led to functional decline. The other three patients improved with shunting and after titration of the shunt had resolution of tremor. Conclusions: We provide evidence that NPH can result in tremor, treatable by shunting. We also emphasize that those patients do exist who have both diseases. This likely exists along a continuum. Careful consideration of NPH should be undertaken in those patients with suspected Parkinson’s disease and imaging findings reminiscent of NPH.

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Clinical series of Parkinson's disease in KwaZulu-Natal, South Africa: Retrospective chart review

Journal of the Neurological Sciences ◽

10.1016/j.jns.2019.03.023 ◽

2019 ◽

Vol 401 ◽

pp. 62-65 ◽

Cited By ~ 2

Author(s):

Ferzana Hassan Amod ◽

Ahmed Iqbal Bhigjee

Keyword(s):

South Africa ◽

Parkinson’S Disease ◽

Parkinson's Disease ◽

Chart Review ◽

Retrospective Chart Review ◽

Clinical Series ◽

Kwazulu Natal

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Use of clozapine in Brazilian patients with Parkinson's disease

Arquivos de Neuro-Psiquiatria ◽

10.1590/s0004-282x2008000500001 ◽

2008 ◽

Vol 66 (3b) ◽

pp. 611-614 ◽

Cited By ~ 9

Author(s):

Laura Gomide ◽

Arthur Kummer ◽

Francisco Cardoso ◽

Antonio Lucio Teixeira

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Adverse Effects ◽

Chart Review ◽

Maximum Dose ◽

Retrospective Chart Review ◽

Advanced Parkinson’S Disease ◽

Brazilian Sample ◽

Average Maximum ◽

Psychiatric Complications

Clozapine has been used as an attempt to manage levodopa complications in advanced Parkinson's disease (PD). To investigate the use of clozapine in this context in a Brazilian sample, a retrospective chart review was carried out at the Movement Disorders Clinic from the Federal University of Minas Gerais. This study enrolled 43 PD patients who used or were in use of clozapine. Patients had a mean age of 64 years and a mean UPDRS score of 55. Clozapine was indicated for dyskinesias in 17 patients, for psychosis in 15 and for both reasons in 11. The average maximum dose was 70 mg/day. Twenty six patients used it for a mean of 3.5 years. Twenty nine presented an improvement of their condition, 9 remained clinically stable. Twenty subjects interrupted the use of clozapine, being 9 due to adverse effects. Clozapine may play a role in the management of motor and psychiatric complications in PD, but it is associated with low tolerability.

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Clinical Characteristics of Pain in Patients with Parkinson’s Disease Who Have Visited a Korean Medical Hospital : A Retrospective Chart Review

Journal of Korean Medicine ◽

10.13048/jkm.20012 ◽

2020 ◽

Vol 41 (2) ◽

pp. 23-33

Author(s):

Hye-Seon Jeong ◽

Ha-Ri Kim ◽

Seo-Yung Kim ◽

Tae-Bin Yim ◽

Chul Jin ◽

...

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Clinical Characteristics ◽

Chart Review ◽

Retrospective Chart Review

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Prevalence of essential tremor in an idiopathic Parkinson’s disease patient population

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques ◽

10.1017/cjn.2015.147 ◽

2015 ◽

Vol 42 (S1) ◽

pp. S31-S31

Author(s):

A Rana ◽

AM Qureshi ◽

MA Rana ◽

M Rahman ◽

I Abdullah ◽

...

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

General Population ◽

Essential Tremor ◽

Chart Review ◽

Disease Patient ◽

Retrospective Chart Review ◽

Type Frequency ◽

Exact Relationship ◽

Mutually Independent

Objective of this study was assess the prevalence of Essential of Essential Tremor in Parkinson’s disease population Essential tremor (ET) is the most common movement disorders and is much more common than Parkinson’s disease, in general population. Essential Tremor and Parkinson’s disease (PD) tremor differ in type, frequency and distribution. Despite being two separate disorders, there have been cases reported of coexistence of ET-PD. Some studies have reported an increase in the incidence of ET in relatives of patients with PD, yet the risk of developing PD in ET patients has not been thoroughly investigated. Our study set out to determine the prevalence of precedent ET in PD patients. We conducted a retrospective chart review analysis of 332 idiopathic PD patients to determine how many of them had ET prior to the diagnosis of PD and the percentage of them who were also diagnosed with ET. Our results indicated that the prevalence of precedent ET among a population of idiopathic PD patients was not any higher than the prevalence of ET in a comparable general population. Our results support the notion that ET and PD are mutually independent disorders. Further studies are needed to understand the exact relationship between these two disorders

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