Complex Adaptive Behavior of Hybrid Teams

Complex Adaptive Behavior: Pragmatic Idealism

Procedia Computer Science ◽

10.1016/j.procs.2016.09.295 ◽

2016 ◽

Vol 95 ◽

pp. 73-79 ◽

Cited By ~ 3

Author(s):

Mustafa Canan ◽

Andres Sousa-Poza

Keyword(s):

Adaptive Behavior ◽

Complex Adaptive

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Adaptive behavior of bacterial mechanosensitive channels is coupled to membrane mechanics

The Journal of General Physiology ◽

10.1085/jgp.200910371 ◽

2010 ◽

Vol 135 (6) ◽

pp. 641-652 ◽

Cited By ~ 51

Author(s):

Vladislav Belyy ◽

Kishore Kamaraju ◽

Bradley Akitake ◽

Andriy Anishkin ◽

Sergei Sukharev

Keyword(s):

Adaptive Behavior ◽

Time Course ◽

Prolonged Exposure ◽

Mechanosensitive Channel ◽

Membrane Mechanics ◽

Response Curves ◽

Channel Opening ◽

Complex Adaptive ◽

Excised Patches ◽

Pressure Adaptation

Mechanosensitive channel of small conductance (MscS), a tension-driven osmolyte release valve residing in the inner membrane of Escherichia coli, exhibits a complex adaptive behavior, whereas its functional counterpart, mechanosensitive channel of large conductance (MscL), was generally considered nonadaptive. In this study, we show that both channels exhibit similar adaptation in excised patches, a process that is completely separable from inactivation prominent only in MscS. When a membrane patch is held under constant pressure, adaptation of both channels is manifested as a reversible current decline. Their dose–response curves recorded with 1–10-s ramps of pressure are shifted toward higher tension relative to the curves measured with series of pulses, indicating decreased tension sensitivity. Prolonged exposure of excised patches to subthreshold tensions further shifts activation curves for both MscS and MscL toward higher tension with similar magnitude and time course. Whole spheroplast MscS recordings performed with simultaneous imaging reveal activation curves with a midpoint tension of 7.8 mN/m and the slope corresponding to ∼15-nm2 in-plane expansion. Inactivation was retained in whole spheroplast mode, but no adaptation was observed. Similarly, whole spheroplast recordings of MscL (V23T mutant) indicated no adaptation, which was present in excised patches. MscS activities tried in spheroplast-attached mode showed no adaptation when the spheroplasts were intact, but permeabilized spheroplasts showed delayed adaptation, suggesting that the presence of membrane breaks or edges causes adaptation. We interpret this in the framework of the mechanics of the bilayer couple linking adaptation of channels in excised patches to the relaxation of the inner leaflet that is not in contact with the glass pipette. Relaxation of one leaflet results in asymmetric redistribution of tension in the bilayer that is less favorable for channel opening.

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Dorsal hippocampus contributes to model-based planning

10.1101/096594 ◽

2016 ◽

Cited By ~ 2

Author(s):

Kevin J. Miller ◽

Matthew M. Botvinick ◽

Carlos D. Brody

Keyword(s):

Adaptive Behavior ◽

Internal Model ◽

Dorsal Hippocampus ◽

Neural Mechanisms ◽

Behavioral Analysis ◽

Model Based ◽

Complex Adaptive ◽

First Time ◽

The Brain

AbstractPlanning can be defined as a process of action selection that leverages an internal model of the environment. Such models provide information about the likely outcomes that will follow each selected action, and their use is a key function underlying complex adaptive behavior. However, the neural mechanisms supporting this ability remain poorly understood. In the present work, we adapt for rodents recent advances from work on human planning, presenting for the first time a task for animals which produces many trials of planned behavior per session, allowing the experimental toolkit available for use in trial-by-trial tasks for rodents to be applied to the study of planning. We take advantage of one part of this toolkit to address a perennially controversial issue in planning research: the role of the dorsal hippocampus. Although prospective representations in the hippocampus have been proposed to support model-based planning, intact planning in hippocampally damaged animals has been observed in a number of assays. Combining formal algorithmic behavioral analysis with muscimol inactivation, we provide the first causal evidence directly linking dorsal hippocampus with planning behavior. The results reported, and the methods introduced, open the door to new and more detailed investigations of the neural mechanisms of planning, in the hippocampus and throughout the brain.

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Nanocrystalline coating design for extreme applications based on the concept of complex adaptive behavior

Journal of Applied Physics ◽

10.1063/1.2904907 ◽

2008 ◽

Vol 103 (8) ◽

pp. 083510 ◽

Cited By ~ 34

Author(s):

G. S. Fox-Rabinovich ◽

S. C. Veldhuis ◽

G. K. Dosbaeva ◽

K. Yamamoto ◽

A. I. Kovalev ◽

...

Keyword(s):

Adaptive Behavior ◽

Nanocrystalline Coating ◽

Complex Adaptive ◽

Coating Design

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Social Communication and Structural Language of Girls With High-Functioning Autism Spectrum Disorder

Language Speech and Hearing Services in Schools ◽

10.1044/2020_lshss-20-00004 ◽

2020 ◽

Vol 51 (4) ◽

pp. 1139-1155

Author(s):

Jenny M. Burton ◽

Nancy A. Creaghead ◽

Noah Silbert ◽

Allison Breit-Smith ◽

Amie W. Duncan ◽

...

Keyword(s):

Autism Spectrum Disorder ◽

Adaptive Behavior ◽

Social Communication ◽

High Functioning Autism ◽

Autism Spectrum ◽

Vineland Adaptive Behavior Scales ◽

High Functioning ◽

Expressive Communication ◽

Vineland Adaptive Behavior ◽

Structural Language

Purpose The purpose of this study was to characterize social communication and structural language of school-age girls with high-functioning autism spectrum disorder (HF-ASD) compared to a matched group of girls who are typically developing (TD). Method Participants were 37 girls between 7;5 and 15;2 (years;months)—18 HF-ASD and 19 TD. Children completed the Test of Pragmatic Language–Second Edition (TOPL-2) and Clinical Evaluation of Language Fundamentals–Fifth Edition. Parents completed the Children's Communication Checklist–2 United States Edition (CCC-2) and Receptive and Expressive Communication subdomains of the Vineland Adaptive Behavior Scales–Second Edition. Results In the area of social communication, girls with HF-ASD earned significantly lower scores and were more often classified as having an impairment on the TOPL-2 and the CCC-2. However, 28% and 33% earned average scores on the TOPL-2 and the CCC-2, respectively. In the area of structural language, no significant differences were found between groups on Clinical Evaluation of Language Fundamentals–Fifth Edition indexes. In contrast, girls with HF-ASD earned significantly lower scores and were more often classified as having an impairment on the Vineland Adaptive Behavior Scales–Second Edition. Sixty-one percent and 83% scored below average on the Receptive and Expressive Communication subdomains, respectively. Conclusions It has been argued that girls with HF-ASD, when compared to boys with HF-ASD, may have advantages for social communication and structural language that mask their impairments. However, when compared to girls who are TD, girls with HF-ASD demonstrated impaired social communication and structural language. Clinicians should include and carefully examine multiple sources of information when assessing girls with HF-ASD.

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