Relationship of in vivo medial temporal lobe magnetic resonance spectroscopy to documented combat exposure in veterans with chronic posttraumatic stress disorder

2005 ◽  
Vol 140 (1) ◽  
pp. 91-94 ◽  
Author(s):  
Tim Kimbrell ◽  
Claire Leulf ◽  
David Cardwell ◽  
Richard A. Komoroski ◽  
Thomas W. Freeman
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Magnetic Resonance ◽  
Magnetic Resonance Spectroscopy ◽  
Posttraumatic Stress ◽  
Medial Temporal Lobe ◽  
Stress Disorder ◽  
Combat Exposure ◽  
Resonance Spectroscopy ◽  
Relationship Of

scholarly journals INSULA AND ANTERIOR CINGULATE GABA LEVELS IN POSTTRAUMATIC STRESS DISORDER: PRELIMINARY FINDINGS USING MAGNETIC RESONANCE SPECTROSCOPY

2013 ◽  
Vol 31 (2) ◽  
pp. 115-123 ◽  
Author(s):  
Isabelle M. Rosso ◽  
Melissa R. Weiner ◽  
David J. Crowley ◽  
Marisa M. Silveri ◽  
Scott L. Rauch ◽  
...  
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Magnetic Resonance ◽  
Magnetic Resonance Spectroscopy ◽  
Posttraumatic Stress ◽  
Stress Disorder ◽  
Anterior Cingulate ◽  
Resonance Spectroscopy

Proton magnetic resonance spectroscopy: an in vivo method of estimating hippocampal neuronal depletion in schizophrenia

1995 ◽  
Vol 25 (6) ◽  
pp. 1201-1209 ◽  
Author(s):  
M. Maier ◽  
M. A. Ron ◽  
G. J. Barker ◽  
P. S. Tofts
Keyword(s):  
Magnetic Resonance ◽  
Magnetic Resonance Spectroscopy ◽  
Medial Temporal Lobe ◽  
Neuronal Loss ◽  
Resonance Spectroscopy ◽  
Neuronal Marker ◽  
Neuronal Populations ◽  
Left Hippocampus ◽  
Diffuse Loss

SynopsisDiffuse loss of cortical volume and ventricular enlargement have been demonstrated in schizophrenia using imaging. In addition, histological studies have provided evidence that the number of neurons in the medial temporal lobe structures is reduced and that the cytoarchitecture is abnormal. In an attempt to correlate these histological findings with in vivo estimates of neuronal integrity we have studied the concentration of the neuronal marker N-acetyl aspartate (NAA) in the hippocampi of schizophrenics using in vivo Magnetic Resonance Spectroscopy (MRS). Compared with a group of healthy volunteers schizophrenics showed a 22% loss of NAA in the left hippocampus. Two other metabolites, choline and creatine showed bilateral reduction in schizophrenics and these achieved significance in the left hippocampus. These results indicate a significant depletion of NAA in schizophrenia and are in close agreement with the reported neuronal loss in the hippocampus detected histologically. We propose that in vivo MRS is a valid measure of integrity of neuronal populations in schizophrenia.

Relationship of Pain, Posttraumatic Stress Disorder, Depression, and Disability in Active-Duty Service Members

2011 ◽  
Author(s):  
Jennifer A. Webb-Murphy ◽  
Steven R. Hanling ◽  
Ivan K. Lesnik ◽  
Stephanie C. Raducha ◽  
Eric T. Stedje-Larsen
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Posttraumatic Stress ◽  
Stress Disorder ◽  
Active Duty ◽  
Service Members ◽  
Relationship Of
Sign in / Sign up

Export Citation Format

Share Document