Salivary cortisol, Alzheimer's disease biomarkers and cognition among memory clinic patients

2017 ◽  
Vol 83 ◽  
pp. 50 ◽  
Author(s):  
Shireen Sindi ◽  
Jasper Holleman ◽  
Sofia Enstedt ◽  
Ingemar Kåreholt ◽  
Miia Kivipelto ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Salivary Cortisol ◽  
Memory Clinic ◽  
Disease Biomarkers

scholarly journals Elevated Norepinephrine Metabolism Gauges Alzheimer’s Disease-Related Pathology and Memory Decline

2021 ◽  
Vol 80 (2) ◽  
pp. 521-526
Author(s):  
Joost M. Riphagen ◽  
Maxime van Egroo ◽  
Heidi I.L. Jacobs
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Dose Response ◽  
Time Trends ◽  
Amyloid Β ◽  
Hyperphosphorylated Tau ◽  
Memory Clinic ◽  
Memory Decline ◽  
Disease Biomarkers ◽  
Norepinephrine Metabolism

The noradrenergic (NE) locus coeruleus (LC) is vulnerable to hyperphosphorylated tau, and dysregulated NE-metabolism is linked to greater tau and disease progression. We investigated whether elevated NE-metabolism alone predicts memory decline or whether concomitant presence of tau and amyloid-β is required. Among 114 memory clinic participants, time trends (max. six years) showed dose-response declines in learning across groups with elevated NE-metabolite 3-methoxy-4-hydroxyphenylethyleneglycol (MHPG) with no, one, or two Alzheimer’s disease biomarkers; and no decline in the low MHPG group. Elevated MHPG is required and sufficient to detect learning declines, supporting a pathophysiologic model including the LC-NE system contributing to initial Alzheimer’s disease-related processes.

scholarly journals Stress and Alzheimer’s disease: Linking salivary cortisol to biomarkers of neurodegeneration and cognitive decline in a memory clinic cohort

2021 ◽  
Vol 17 (S5) ◽  
Author(s):  
Makrina Daniilidou ◽  
Göran Hagman ◽  
Jasper Holleman ◽  
Shireen Sindi ◽  
Ann Brinkmalm ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Decline ◽  
Salivary Cortisol ◽  
Memory Clinic

O2-09-03: DIAGNOSTIC PERFORMANCE OF ELECSYS IMMUNOASSAYS FOR CEREBROSPINAL FLUID ALZHEIMER'S DISEASE BIOMARKERS IN A NON-ACADEMIC MULTICENTER MEMORY CLINIC COHORT: THE ABIDE PROJECT

2006 ◽  
Vol 14 (7S_Part_11) ◽  
pp. P641-P642
Author(s):  
Eline A.J. Willemse ◽  
Ingrid S. van Maurik ◽  
Betty M. Tijms ◽  
Andreas Franke ◽  
Isabelle Hubeek ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cerebrospinal Fluid ◽  
Diagnostic Performance ◽  
Memory Clinic ◽  
Disease Biomarkers

scholarly journals Association of CSF Alzheimer's disease biomarkers with postoperative delirium in older adults

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Tamara G. Fong ◽  
Sarinnapha M. Vasunilashorn ◽  
Yun Gou ◽  
Towia A. Libermann ◽  
Simon Dillon ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Older Adults ◽  
Alzheimer's Disease ◽  
Postoperative Delirium ◽  
Disease Biomarkers

scholarly journals Correlation between oligomerizaton of amyloid beta in plasma and other Alzheimer's disease biomarkers

IBRO Reports ◽  
2019 ◽  
Vol 6 ◽  
pp. S91
Author(s):  
Sungmin Kang ◽  
Jeewon Suh ◽  
Jeong Min Pyun ◽  
Young Chul Youn ◽  
Ji Sun Yu ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Amyloid Beta ◽  
Disease Biomarkers

scholarly journals Pre‐analytical protocol for measuring Alzheimer's disease biomarkers in fresh CSF

2020 ◽  
Vol 12 (1) ◽  
Author(s):  
Oskar Hansson ◽  
Sandra Rutz ◽  
Henrik Zetterberg ◽  
Ekaterina Bauer ◽  
Teresa Hähl ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Disease Biomarkers ◽  
Analytical Protocol
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