scholarly journals Advanced parametric imaging for evaluation of Crohn's disease using dual-energy computed tomography enterography

2018 ◽  
Vol 13 (3) ◽  
pp. 709-712
Author(s):  
Narumi Taguchi ◽  
Seitaro Oda ◽  
Tateaki Kobayashi ◽  
Hideaki Naoe ◽  
Yutaka Sasaki ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Dual Energy ◽  
Parametric Imaging ◽  
Dual Energy Computed Tomography ◽  
Computed Tomography Enterography

scholarly journals Efficiency of dual-energy computed tomography enterography in the diagnosis of Crohn’s disease

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Jinghao Chen ◽  
Jie Zhou ◽  
Jushun Yang ◽  
Ruochen Cong ◽  
Jinjie Sun ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Dual Energy ◽  
Diagnostic Efficiency ◽  
Diagnostic Efficacy ◽  
Dual Energy Computed Tomography ◽  
Computed Tomography Enterography ◽  
Monoenergetic Imaging ◽  
Iodine Map

Abstract Background This retrospective study aimed to investigate the usefulness of the optimized kiloelectron volt (keV) for virtual monoenergetic imaging (VMI) combined with iodine map in dual-energy computed tomography enterography (DECTE) in the diagnosis of Crohn’s disease (CD). Methods Seventy-two patients (mean age: 41.89 ± 17.28 years) with negative computed tomography enterography (CTE) were enrolled for investigating the optimized VMI keV in DECTE by comparing subjective and objective parameters of VMIs that were reconstructed from 40 to 90 keV. Moreover, 68 patients (38.27 ± 15.10 years; 35 normal and 33 CD) were included for evaluating the diagnostic efficacy of DECTE iodine map at the optimized VMI energy level and routine CTE for CD and active CD. Statistical analysis for all data was conducted. Results Objective and subjective imaging evaluations showed the best results at 60 keV for VMIs. The CT values of the normal group, active subgroup, and CD group during the small intestinal phase at routine 120 kVp or 60 keV VMI had significant differences. The diagnostic efficacy of an iodine map was the best when NIC = 4% or fat value = 45.8% for CD, whereas NIC < 0.35 or the fat value < 0.38 for active CD. The combined routine CTE and optimized VMI improved the diagnostic efficacy (P < 0.001). Conclusions VMI at 60 keV provided the best imaging quality on DECTE. NIC and fat value provided important basis for active CD evaluation. Routine CTE combined with VMI at 60 keV improved the diagnostic efficiency for CD.

S1221 Computed Tomography Enterography and Small Bowel Ultrasound in Assessing Ileal Crohn's Disease Activity

2008 ◽  
Vol 134 (4) ◽  
pp. A-204
Author(s):  
Alessandra Losco ◽  
Chiara Trattenero ◽  
Mirella Fraquelli ◽  
Laura Virginia Forzenigo ◽  
Sara Massironi ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Crohn’S Disease ◽  
Small Bowel ◽  
Crohn's Disease ◽  
Disease Activity ◽  
Computed Tomography Enterography ◽  
Crohn’S Disease Activity ◽  
Bowel Ultrasound

Crohn's disease recurrence in patients with ileocolic anastomosis: Value of computed tomography enterography with water enema

2013 ◽  
Vol 82 (9) ◽  
pp. e434-e440 ◽  
Author(s):  
Francesco Paparo ◽  
Matteo Revelli ◽  
Cristina Puppo ◽  
Lorenzo Bacigalupo ◽  
Isabella Garello ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Disease Recurrence ◽  
Ileocolic Anastomosis ◽  
Computed Tomography Enterography

651 Small Bowel Ultrasound and Computed Tomography Enterography: Characteristics of Bowel Wall and Mesenteric Tissue in the First Diagnosis of Ileal Crohn's Disease

2009 ◽  
Vol 136 (5) ◽  
pp. A-99
Author(s):  
Chiara Trattenero ◽  
Alessandra Losco ◽  
Mirella Fraquelli ◽  
Laura Virginia Forzenigo ◽  
Valentina Sciola ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Crohn’S Disease ◽  
Small Bowel ◽  
Crohn's Disease ◽  
Bowel Wall ◽  
Computed Tomography Enterography ◽  
Bowel Ultrasound ◽  
First Diagnosis

scholarly journals Monitoring Crohn’s disease activity: endoscopy, fecal markers and computed tomography enterography

2018 ◽  
Vol 11 ◽  
pp. 175628481876907 ◽  
Author(s):  
Susana Lopes ◽  
Patrícia Andrade ◽  
Joana Afonso ◽  
Rui Cunha ◽  
Eduardo Rodrigues-Pinto ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Disease Activity ◽  
Rank Correlation ◽  
Response To Therapy ◽  
Newly Diagnosed ◽  
Mesenteric Fat ◽  
Computed Tomography Enterography

Background: The treatment goal of Crohn’s disease (CD) has moved towards achieving mucosal healing, resolution of transmural inflammation, and normalization of biomarkers. The purpose of this study was to evaluate how well computed tomography enterography (CTE) and fecal calprotectin (FC) correlated with endoscopic activity in newly diagnosed patients with CD and after 1 year of therapy. Methods: Consecutive patients with newly diagnosed CD were evaluated by endoscopy, CTE, and FC at diagnosis and 12 months after beginning immunosuppression. Endoscopic severity was assessed using the Simplified Endoscopic Score for Crohn’s Disease (SES-CD). Biomarkers, clinical indexes, and FC were recorded on the day of ileocolonoscopy at diagnosis and 1 year after diagnosis. We adapted a CTE score for disease activity based on radiological signs of inflammation (i.e. mural thickness, mural hyperenhancement, mesenteric fat proliferation, mesenteric fat densification, comb sign, presence of strictures, fistulas, abscesses, ascites, and lymphadenopathy). Correlations between endoscopy, CTE, and FC were assessed using Spearman’s rank correlation. Results: A total of 29 patients (48% women; median age 30 (24.5–35.5) years) were included in this prospective cohort. CTE findings significantly correlated with endoscopic findings. Endoscopic remission (ER) at 1-year follow up significantly correlated with improvement in mural hyperenhancement ( p = 0.004), mesenteric fat densification ( p = 0.001), comb sign ( p = 0.004), and strictures ( p = 0.008) in CTE. None of the CTE findings improved in patients without ER. FC correlated with SES-CD ( rs = 0.696, p < 0.001) and with CTE features of inflammation ( rs = 0.596, p < 0.001). A cut-off of 100 µg/g predicted ER with 92% sensitivity, 65% specificity, and 83% accuracy (area under curve 0.878, p < 0.001). Conclusions: CTE findings and FC levels correlated with endoscopic activity in CD both at diagnosis and at 1-year follow up. These two noninvasive markers of disease activity may be used as an alternative to endoscopy to monitor disease response to therapy.

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