scholarly journals Determining the need for fertility care and the acceptability and feasibility of administering a fertility awareness tool from the user’s perspective in a sample of Sudanese infertility patients

2021 ◽  
Author(s):  
R.R. Bayoumi ◽  
E. Koert ◽  
S. Van der Poel ◽  
J. Boivin
Keyword(s):  
Fertility Awareness ◽  
Awareness Tool ◽  
Infertility Patients

scholarly journals Effects of controlled ovarian stimulation on vascular barrier and endothelial glycocalyx: a pilot study

2021 ◽  
Author(s):  
Nikolai Hulde ◽  
N. Rogenhofer ◽  
F. Brettner ◽  
N. C. Eckert ◽  
I. Fetz ◽  
...  
Keyword(s):  
Ovarian Stimulation ◽  
Capillary Permeability ◽  
Serum Levels ◽  
Controlled Ovarian Stimulation ◽  
Endothelial Glycocalyx ◽  
Control Group ◽  
Vascular Integrity ◽  
Fluid Extravasation ◽  
Endothelial Surface ◽  
Infertility Patients

Abstract Purpose Controlled ovarian stimulation significantly amplifies the number of maturing and ovulated follicles as well as ovarian steroid production. The ovarian hyperstimulation syndrome (OHSS) increases capillary permeability and fluid extravasation. Vascular integrity intensely is regulated by an endothelial glycocalyx (EGX) and we have shown that ovulatory cycles are associated with shedding of EGX components. This study investigates if controlled ovarian stimulation impacts on the integrity of the endothelial glycocalyx as this might explain key pathomechanisms of the OHSS. Methods Serum levels of endothelial glycocalyx components of infertility patients (n=18) undergoing controlled ovarian stimulation were compared to a control group of healthy women with regular ovulatory cycles (n=17). Results Patients during luteal phases of controlled ovarian stimulation cycles as compared to normal ovulatory cycles showed significantly increased Syndecan-1 serum concentrations (12.6 ng/ml 6.1125th–19.1375th to 13.9 ng/ml 9.625th–28.975th; p=0.026), indicating shedding and degradation of the EGX. Conclusion A shedding of EGX components during ovarian stimulation has not yet been described. Our study suggests that ovarian stimulation may affect the integrity of the endothelial surface layer and increasing vascular permeability. This could explain key features of the OHSS and provide new ways of prevention of this serious condition of assisted reproduction.

scholarly journals Use of fertility awareness methods as a component of safer conception for women in HIV-serodifferent relationships in Kenya

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Yasaman Zia ◽  
Jennifer Velloza ◽  
Lynda Oluoch ◽  
Richard Momanyi ◽  
Sarah Mbugua ◽  
...  
Keyword(s):  
Hiv Transmission ◽  
Proportional Hazards ◽  
Cox Proportional Hazards ◽  
Cervical Mucus ◽  
Safer Conception ◽  
Open Label ◽  
Fertility Awareness ◽  
Menstrual Cycles ◽  
Condomless Sex ◽  
Message Service

Abstract Background For couples affected by HIV, and serodifferent couples in particular, pregnancy desire is often juxtaposed against the risk of HIV transmission between the couple and the potential neonate leading to thinking about measures to minimize risk of HIV transmission. We assess the use of fertility awareness methods [FAM] and evaluate the drivers of alignment between indicators of fertility and sexual behavior among HIV-serodifferent couples desiring pregnancy. Methods HIV-serodifferent couples from Thika, Kenya were enrolled into an open-label pilot evaluation of safer conception strategies. Women responded to daily 7-item short message service [SMS] surveys on FAM and sexual activity. Menstrual cycles were categorized as having condomless sex aligned, not aligned, or partially aligned to the predicted peak fertility. We used binomial logit models with generalized estimating equations to assess alignment between condomless sex during peak fertility days and FAM results. We used Cox proportional hazards to compare pregnancy incidence among months with sex and peak fertility aligned and mis-aligned. Results A total of 6929 SMS surveys across 252 menstrual cycles of 65 women were included. Reporting “sticky” cervical mucus (adjusted odds ratio [aOR]: 2.25, 95% confidence interval [95% CI]: 1.30, 3.90) and positive ovulation prediction kit [OPK] result (aOR: 2.07, 95% CI: 1.11, 3.86) were associated with increased likelihood of alignment of condomless sex during peak fertility. Pregnancy incidence was statistically similar among periods with sex aligned and not aligned with peak fertility. Conclusions Among women engaged in a comprehensive safer conception program, a moderate percentage of women aligned condomless sex and predicted peak fertility days at least once. While FAM, particularly cervical mucus and OPK, are an inexpensive option for couples to consider using as a component of their safer conception strategies, antiretroviral-based strategies remain important to minimize risk.

scholarly journals Promoting regulation of equal participation in online collaboration by combining a group awareness tool and adaptive prompts. But does it even matter?

2021 ◽  
Author(s):  
Sebastian Strauß ◽  
Nikol Rummel
Keyword(s):  
Collaborative Learning ◽  
Online Collaboration ◽  
Online Course ◽  
Group Awareness ◽  
Web Based ◽  
Equal Distribution ◽  
Action Sequences ◽  
Awareness Tool ◽  
University Level ◽  
Additional Support

AbstractUnequal participation poses a challenge to collaborative learning because it reduces opportunities for fruitful collaboration among learners and affects learners’ satisfaction. Social group awareness tools can display information on the distribution of participation and thus encourage groups to regulate the distribution of participation. However, some groups might require additional explicit support to leverage the information from such a tool. Therefore, this study investigated the effect of combining a group awareness tool and adaptive collaboration prompts on the distribution of participation during web-based collaboration. In this field experiment, students in a university level online course collaborated twice for two-weeks (16 groups in the first task; 13 groups in the second task) and either received only a group awareness tool, a combination of a group awareness tool and adaptive collaboration prompts, or no additional support. Our results showed that students were more satisfied when the participation in their group was more evenly distributed. However, we only found tentative support that the collaboration support helped groups achieve equal participation. Students reported rarely using the support for shared regulation of participation. Sequence alignment and clustering of action sequences revealed that groups who initiated the collaboration early, coordinated before solving the problem and interacted continuously tended to achieve an equal distribution of participation and were more satisfied with the collaboration. Against the background of our results, we identify potential ways to improve group awareness tools for supporting groups in their regulation of participation, and discuss the premise of equal participation during collaborative learning.

Peritoneal fluid and serum steroids in infertility patients

1984 ◽  
Vol 42 (2) ◽  
pp. 237-242 ◽  
Author(s):  
Philip R. Lesorgen ◽  
Chung H. Wu ◽  
Paul J. Green ◽  
Benjamin Gocial ◽  
Leonard J. Lerner
Keyword(s):  
Peritoneal Fluid ◽  
Infertility Patients

Evaluating γH2AX in spermatozoa from male infertility patients

2015 ◽  
Vol 104 (3) ◽  
pp. 574-581 ◽  
Author(s):  
Hui-zhi Zhong ◽  
Fu-tong Lv ◽  
Xue-lian Deng ◽  
Ying Hu ◽  
Dan-ni Xie ◽  
...  
Keyword(s):  
Male Infertility ◽  
Infertility Patients

Laparoscopic proximal tubal division can preserve ovarian reserve for infertility patients with hydrosalpinges

2008 ◽  
pp. ???-??? ◽  
Author(s):  
Koji Nakagawa ◽  
Shirei Ohgi ◽  
Akira Nakashima ◽  
Takashi Horikawa ◽  
Minoru Irahara ◽  
...  
Keyword(s):  
Ovarian Reserve ◽  
Infertility Patients

Diagnosing the Conditional Probability of Tornado Damage Rating Using Environmental and Radar Attributes

2015 ◽  
Vol 30 (4) ◽  
pp. 914-932 ◽  
Author(s):  
Bryan T. Smith ◽  
Richard L. Thompson ◽  
Andrew R. Dean ◽  
Patrick T. Marsh
Keyword(s):  
Conditional Probability ◽  
Situational Awareness ◽  
Rotational Velocity ◽  
Environmental Data ◽  
Doppler Data ◽  
Awareness Tool ◽  
Tornado Event ◽  
Tornado Damage ◽  
Segment Data ◽  
Horizontal Grid

Abstract Radar-identified convective modes, peak low-level rotational velocities, and near-storm environmental data were assigned to a sample of tornadoes reported in the contiguous United States during 2009–13. The tornado segment data were filtered by the maximum enhanced Fujita (EF)-scale tornado event per hour using a 40-km horizontal grid. Convective mode was assigned to each tornado event by examining full volumetric Weather Surveillance Radar-1988 Doppler data at the beginning time of each event, and 0.5° peak rotational velocity (Vrot) data were identified manually during the life span of each tornado event. Environmental information accompanied each grid-hour event, consisting primarily of supercell-related convective parameters from the hourly objective mesoscale analyses calculated and archived at the Storm Prediction Center. Results from examining environmental and radar attributes, featuring the significant tornado parameter (STP) and 0.5° peak Vrot data, suggest an increasing conditional probability for greater EF-scale damage as both STP and 0.5° peak Vrot increase, especially with supercells. Possible applications of these findings include using the conditional probability of tornado intensity as a real-time situational awareness tool.

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