<p>Implementation of Bridge weigh-in-motion (B-WIM) measurements and probabilistic approaches in bridge assessment may reveal hidden bridge reserves and changes in reliability levels over their projected service life, providing a key input for optimized bridge management. But, as scientists and engineers and at the same time vendors of our own ideas, we need to be in position to present the results of our sophisticated methods and algorithms, expressed mostly in terms of safety or reliability indexes, probabilities of failures and similar indicators, with expected monetary savings which are decisive for an owner or an investor.</p><p>In previous research, as presented at the COST TU1402 special session in Nantes 2018, in order to define the optimal management bridge strategy, a decision tree encompassing three B-WIM strategies (no B-WIM, short term B-WIM, long term B-WIM), two possible activities (no action, bridge repair/strengthening) and two possible outcomes (bridge is safe, bridge may experience failure) have been formulated.</p><p>In this paper, a further development of the decision and Value of B-WIM Information analysis in the context of assessing road bridges are discussed.</p><p>The focus in the present paper is directed on a detailed assessment and modelling of costs, benefits and associated indicators related to the probability of bridge failure. Costs required for the Value of Information analysis encompass: (i) the initial cost of the new bridge CBV, (ii) direct costs of bridge repair/strengthening <i>C</i>rep, (iii) indirect costs of bridge non-availability due to repair measures <i>C</i>N/A, and costs of B-WIM measurements (iv) <i>C</i>B-WIM,1 and (v) <i>C</i>B-WIM 2, applying short- or long-term monitoring respectively.</p>
Decisions on Further Research for Predictive Biomarkers of High-Dose Alkylating Chemotherapy in Triple-Negative Breast Cancer: A Value of Information Analysis
