Patent ductus arteriosus and cerebral, cardiac, and gut hemodynamics in premature neonates

2020 ◽  
Vol 25 (5) ◽  
pp. 101120
Author(s):  
J.L. Ruoss ◽  
C. Bazacliu ◽  
R.E. Giesinger ◽  
P.J. McNamara
Keyword(s):  
Patent Ductus Arteriosus ◽  
Ductus Arteriosus ◽  
Premature Neonates ◽  
Patent Ductus

Ligation of Patent Ductus Arteriosus in Premature Neonates

1981 ◽  
Vol 74 (1) ◽  
pp. 21-23 ◽  
Author(s):  
BRENDAN T. FINUCANE ◽  
PETER N. SYMBAS ◽  
REBECCA BRASWELL ◽  
Atlanta Ga
Keyword(s):  
Patent Ductus Arteriosus ◽  
Ductus Arteriosus ◽  
Premature Neonates ◽  
Patent Ductus

scholarly journals Patent Ductus Arteriosus in Premature Neonates

Drugs ◽  
2012 ◽  
Vol 72 (7) ◽  
pp. 907-916 ◽  
Author(s):  
Olachi J. Mezu-Ndubuisi ◽  
Ghanshyam Agarwal ◽  
Aarti Raghavan ◽  
Jennifer T. Pham ◽  
Kirsten H. Ohler ◽  
...  
Keyword(s):  
Patent Ductus Arteriosus ◽  
Ductus Arteriosus ◽  
Premature Neonates ◽  
Patent Ductus

Transient Dynamic Subaortic Stenosis in Premature Neonates After Patent Ductus Arteriosus Ligation

2007 ◽  
Vol 29 (5) ◽  
pp. 989-992
Author(s):  
Madhavi Sangem ◽  
Mubadda A. Salim ◽  
Jon C. Love ◽  
A. Okogbule-Wonodi ◽  
Marcelo G. Cardarelli
Keyword(s):  
Patent Ductus Arteriosus ◽  
Ductus Arteriosus ◽  
Subaortic Stenosis ◽  
Premature Neonates ◽  
Transient Dynamic ◽  
Patent Ductus

Myocardial Contractility in Premature Neonates With and Without Patent Ductus Arteriosus

2004 ◽  
Vol 25 (2) ◽  
pp. 102-107 ◽  
Author(s):  
J.E. Potts ◽  
G.G.S. Sandor ◽  
A. J. Barlow ◽  
B. G. Sinclair ◽  
C. Ward ◽  
...  
Keyword(s):  
Patent Ductus Arteriosus ◽  
Myocardial Contractility ◽  
Ductus Arteriosus ◽  
Premature Neonates ◽  
Patent Ductus

Surgical closure of patent ductus arteriosus in premature neonates: Does the surgical technique affect the outcome?

2017 ◽  
Vol 86 (5) ◽  
pp. 277-283 ◽  
Author(s):  
Alejandro Avila-Alvarez ◽  
Marta Serantes Lourido ◽  
Rebeca Barriga Bujan ◽  
Carolina Blanco Rodriguez ◽  
Francisco Portela-Torron ◽  
...  
Keyword(s):  
Surgical Technique ◽  
Patent Ductus Arteriosus ◽  
Ductus Arteriosus ◽  
Premature Neonates ◽  
Surgical Closure ◽  
Patent Ductus

The Use of a Bedside Assay for Plasma B-type Natriuretic Peptide as a Biomarker in the Management of Patent Ductus Arteriosus in Premature Neonates

2005 ◽  
Vol 147 (1) ◽  
pp. 38-42 ◽  
Author(s):  
Patrick A. Flynn ◽  
Ralph L. da Graca ◽  
Peter A.M. Auld ◽  
Mirjana Nesin ◽  
Charles S. Kleinman
Keyword(s):  
Patent Ductus Arteriosus ◽  
Natriuretic Peptide ◽  
Ductus Arteriosus ◽  
Premature Neonates ◽  
Patent Ductus

scholarly journals Objective Assessment of Physiologic Alterations Associated With Hemodynamically Significant Patent Ductus Arteriosus in Extremely Premature Neonates

2021 ◽  
Vol 9 ◽  
Author(s):  
Aparna Patra ◽  
Pratibha S. Thakkar ◽  
Majd Makhoul ◽  
Henrietta S. Bada
Keyword(s):  
Cardiac Output ◽  
Patent Ductus Arteriosus ◽  
Clinical Care ◽  
Objective Assessment ◽  
Ductus Arteriosus ◽  
Clinical Signs ◽  
Tissue Perfusion ◽  
Postnatal Life ◽  
Premature Neonates ◽  
Patent Ductus

Delay in closure of ductus arteriosus in postnatal life may lead to serious consequences and complications in an extremely premature neonate secondary to hemodynamic alterations in regional blood flow pattern in various organs. Despite the widespread recognition amongst neonatologists to identify a hemodynamically significant patent ductus arteriosus (hsPDA) early in the postnatal course, there is lack of consensus in its definition and thus the threshold to initiate treatment. Echocardiographic assessment of PDA shunt size and volume combined with neonatologists' impression of clinical significance is most frequently used to determine the need for treatment of PDA. Common clinical signs of hsPDA utilized as surrogate for decreased tissue perfusion may lag behind early echocardiographic signs. Although echocardiogram allows direct assessment of PDA shunt and hemodynamic alterations in the heart, it is limited by dependence on pediatric cardiologist availability, interobserver variation and isolated time point assessment. Electrical cardiometry (EC) is a non-invasive continuous real time measurement of cardiac output by applying changes in thoracic electrical impedance. EC has been validated in preterm newborns by concomitant transthoracic echocardiogram assessments and may be beneficial in studying changes in cardiac output in premature newborns with hsPDA. Alterations in perfusion index derived from continuous pulse oximetry monitoring has been used to study changes in cardiac performance and tissue perfusion in infants with PDA. Near infrared spectroscopy (NIRS) has been used to objectively and continuously assess variations in renal, mesenteric, and cerebral oxygen saturation and thus perfusion changes due to diastolic vascular steal from hsPDA in preterm neonates. Doppler ultrasound studies measuring resistive indices in cerebral circulation indicate disturbance in cerebral perfusion secondary to ductal steal. With recent trends of change in practice toward less intervention in care of preterm newborn, treatment strategy needs to be targeted for select preterm population most vulnerable to adverse hemodynamic effects of PDA. Integration of these novel ways of hemodynamic and tissue perfusion assessment in routine clinical care may help mitigate the challenges in defining and targeting treatment of hsPDA thereby improving outcomes in extremely premature neonates.

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