Association between Modic changes, disc degeneration, and neck pain in the cervical spine: a systematic review of literature

2020 ◽  
Vol 20 (5) ◽  
pp. 754-764 ◽  
Author(s):  
Xiaoyu Yang ◽  
Diederik S.A. Karis ◽  
Carmen L.A. Vleggeert-Lankamp
Keyword(s):  
Systematic Review ◽  
Cervical Spine ◽  
Neck Pain ◽  
Disc Degeneration ◽  
Modic Changes ◽  
Review Of Literature

Effect of Different Types of Modic Changes on Segmental Motion and Disc Degeneration in Cervical Spine

2020 ◽  
Author(s):  
Fan Zhang ◽  
Jin Wang ◽  
Haocheng Xu ◽  
Feizhou Lyu
Keyword(s):  
Cervical Spine ◽  
Neck Pain ◽  
Disc Degeneration ◽  
Modic Changes ◽  
Angular Motion ◽  
Segmental Motion ◽  
C7 Slope ◽  
Different Types ◽  
Close Relationship ◽  
Motion Characteristics

Abstract Background: Few studies have reported the segmental motion characteristics of different types of Modic changes (MCs) in the cervical spine in contrast to the lumbar spine. Considering the close relationship between MCs and disc degeneration (DD), this study is designed to elucidate the relationship of MCs with DD and DD-based angular motion in the cervical spine.Methods: MRI of C2/3~C6/7 from 594 patients were reviewed and those with MCs were selected and evaluated. MCs were defined as type 0, I, II, and III, and the grade of DD was classified from A to E (recorded from 1 to 5 points) as previously reported. DD score of each segment (sDD), total sDD of the entire cervical spine (tDD), and VAS score (neck pain) of each patient with MC were also recorded. Cervical lordosis (CL), C7 slope (C7S), segmental angular motion (sROM) and total angular motion of the entire cervical spine (tROM) were calculated from X-ray images.Results: Totally 135 MC segments were evaluated. In the two groups of DD D and DD E, the sROM of MC I and III segments are smaller than that of MC 0 segments, and the sROM of MC II segments are similar to that of MC 0. In addition, MC I segments present smaller sROM than that of MC II in the group of DD E, and their sROM are larger than that of MC III in the group of DD D. No difference is found in tROM between the patients with MC I, II and III. Our results also show that MC I and III segments are associated with high sDD and tDD scores. Finally, the patients with MC I have larger CL and C7S than those with MC III, and there is no statistical difference in VAS scores of neck pain between the patients with MC I, II and III. Conclusions: In the cervical spine, both MC I and III indicate decreased segmental angular motion and high disc degeneration grade. Cervical MCs may not be a sign of unstable neck pain or an indication for interbody fusion.

Biomechanical Effects of Chiropractic-Based Distraction Therapy on the Behavior of Healthy and Degenerated Cervical Discs: A Finite Element Model Analysis

2009 ◽  
Author(s):  
Mozammil Hussain ◽  
Ralph E. Gay ◽  
Kai-Nan An ◽  
Rodger Tepe
Keyword(s):  
Finite Element ◽  
Cervical Spine ◽  
Neck Pain ◽  
Finite Element Model ◽  
Disc Degeneration ◽  
Element Model ◽  
Model Analysis ◽  
Biochemical Changes ◽  
Tissue Properties ◽  
Disc Tissue

Many neck pain complaints are associated with degenerated discs in cervical spine. Disc degeneration (DD) consists of cascading stages of events with complex changes in disc tissue properties. This results in deterioration of the ability of the disc to perform its function normally. Several biomechanical and biochemical changes occur in the disc with degeneration. Increase in motion segment stiffness and peak stresses in the posterior annulus are some of the gross changes that occur in the disc with degeneration.

Cervical spine findings on MRI in people with neck pain compared with pain‐free controls: A systematic review and meta‐analysis

2019 ◽  
Vol 49 (6) ◽  
pp. 1638-1654 ◽  
Author(s):  
Scott F. Farrell ◽  
Ashley D. Smith ◽  
Mark J. Hancock ◽  
Alexandra L. Webb ◽  
Michele Sterling
Keyword(s):  
Systematic Review ◽  
Cervical Spine ◽  
Neck Pain ◽  
Meta Analysis

Adolescent Disc Degeneration - No Headache Association

Cephalalgia ◽  
2007 ◽  
Vol 27 (1) ◽  
pp. 14-21 ◽  
Author(s):  
K Laimi ◽  
M Erkintalo ◽  
L Metsähonkala ◽  
T Vahlberg ◽  
M Mikkelsson ◽  
...  
Keyword(s):  
Cervical Spine ◽  
Neck Pain ◽  
Disc Degeneration ◽  
Population Based ◽  
Degenerative Changes ◽  
Resonance Imaging ◽  
Mri Scans ◽  
Magnetic Resonance Imaging Mri ◽  
Mri Study

The objective of the study was to determine whether adolescents with headache have more disc degeneration in the cervical spine than headache-free controls. This study is part of a population-based follow-up study of adolescents with and without headache. At the age of 17 years, adolescents with headache at least three times a month ( N = 47) and adolescents with no headache ( N = 22) participated in a magnetic resonance imaging (MRI) study of the cervical spine. Of the 47 headache sufferers, 17 also had weekly neck pain and 30 had neck pain less than once a month. MRI scans were interpreted independently by three neuroradiologists. Disc degeneration was found in 67% of participants, with no difference between adolescents with and without headache. Most of the degenerative changes were located in the lower cervical spine. In adolescence, mild degenerative changes of the cervical spine are surprisingly common but do not contribute to headache.

scholarly journals A non-linear multiaxial fatigue damage model for the cervical intervertebral disc annulus

2018 ◽  
Vol 10 (6) ◽  
pp. 168781401877949 ◽  
Author(s):  
Shruti Motiwale ◽  
Adhitya Subramani ◽  
Reuben H Kraft ◽  
Xianlian Zhou
Keyword(s):  
Cervical Spine ◽  
Cyclic Loading ◽  
Neck Pain ◽  
Intervertebral Disc ◽  
Fatigue Damage ◽  
Disc Degeneration ◽  
Intervertebral Discs ◽  
Quantitative Prediction ◽  
Biomechanical Models ◽  
Non Linear

A significant portion of the military population develops severe neck pain in the course of their duties. It has been hypothesized that neck pain is a consequence of accelerated degeneration of the intervertebral discs in the cervical spine, but more occupational and mechanistic-based tools and research are needed to positively confirm the link between neck pain and accelerated disc degeneration. Heavy head-supported mass including helmets and accessories worn by military personnel may subject the intervertebral discs of the cervical spine to complex cyclic loading profiles. In addition, some military operational travel which includes riding on high speed planing boats has also been reported to result in high magnitude cyclic loading on cervical spine discs. In this article, we present a methodology to computationally predict fatigue damage to cervical intervertebral discs over extended periods of time, by integrating kinematics-based biomechanical models with a continuum damage mechanics-based theory of disc degeneration. Through this computational approach, we can gain insights into the relationship between these military activities and possible accelerated fatigue degeneration of cervical intervertebral discs and provide a quantitative prediction tool for decade-long time ranges. The four significant improvements this computational framework adds to the area of modeling intervertebral disc degeneration are the following: (a) it addresses the non-linear nature of fatigue damage evolution, (b) it includes the effect of aging and damage recovery to accurately simulate biological phenomena, (c) it computes fatigue damage taking into account the multiaxial stress state in the disc, and (d) it correlates the computational damage parameter with established clinical grading systems for disc degeneration.

Adolescent cervical disc degeneration in MRI does not predict adult headache or neck pain: A 5-year follow-up of adolescents with and without headache

Cephalalgia ◽  
2014 ◽  
Vol 34 (9) ◽  
pp. 679-685 ◽  
Author(s):  
Katri Laimi ◽  
Johanna Pitkänen ◽  
Liisa Metsähonkala ◽  
Tero Vahlberg ◽  
Marja Mikkelsson ◽  
...  
Keyword(s):  
Cervical Spine ◽  
Neck Pain ◽  
Disc Degeneration ◽  
Degenerative Changes ◽  
Cervical Disc ◽  
Resonance Imaging ◽  
Magnetic Resonance Imaging Mri ◽  
Mri Study ◽  
The Impact

Aim The impact of early degenerative changes of the cervical spine on pain in adulthood is unknown. The objective was to determine whether degeneration in adolescence predicts headache or neck pain in young adulthood. Methods As part of a follow-up of schoolchildren with and without headache, 17-year-old adolescents with headache at least three times a month ( N = 47) and adolescents with no headache ( N = 22) participated in a magnetic resonance imaging (MRI) study of the cervical spine. The same adolescents were re-examined by phone interview at the age of 22 years ( N = 60/69, 87%). Results Mild disc degeneration at the age of 17 years was common, but was not associated with either frequent or intensive headache or neck pain at the age of 22 years. Conclusion: Mild degenerative changes of the cervical spine in 17-year-old adolescents cannot be regarded as a cause of future headache or neck pain.

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