5-lipoxygenase activation is involved in the mechanisms of chronic hepatic injury in a rat model of chronic aluminum overload exposure

2016 ◽  
Vol 305 ◽  
pp. 259-266 ◽  
Author(s):  
Shaoshan Mai ◽  
Qin He ◽  
Hong Wang ◽  
Xinyue Hu ◽  
Ying Luo ◽  
...  
1966 ◽  
Vol 22 (10) ◽  
pp. 701-702 ◽  
Author(s):  
R. Preisig ◽  
D. Gocke ◽  
T. Morris ◽  
S. E. Bradley

1993 ◽  
Vol 28 (Supplement_1A) ◽  
pp. 111-117 ◽  
Author(s):  
Hiroshi Suzuki ◽  
Tomoya Tominaga ◽  
Hiroshi Mizuno ◽  
Mayumi Kouno ◽  
Michihiro Suzuki ◽  
...  

1981 ◽  
Vol 80 (4) ◽  
pp. 647-654 ◽  
Author(s):  
Andrew Tanner ◽  
Abdol Keyhani ◽  
Rick Reiner ◽  
Greg Holdstock ◽  
Ralph Wright

Biomolecules ◽  
2015 ◽  
Vol 5 (4) ◽  
pp. 3295-3308 ◽  
Author(s):  
Nicholas Szary ◽  
R. Rector ◽  
Grace Uptergrove ◽  
Suzanne Ridenhour ◽  
Shivendra Shukla ◽  
...  

2018 ◽  
Vol 50 (1) ◽  
pp. 4-5
Author(s):  
M. Crescenzi ◽  
C. Frasson ◽  
M.F. Secchi ◽  
P. Burra ◽  
G. Basso ◽  
...  

J ◽  
2020 ◽  
Vol 3 (1) ◽  
pp. 54-66
Author(s):  
Hee-Young Ahn ◽  
Young-Su Cho

We compared hepatoprotective effects between fermented rice bran (FRB) and fermented rice germ and soybean (FRS) in a Sprague-Dawley (SD) rat model of alcohol-induced hepatic injury (AIHI). To establish an SD rat model of AIHI, the SD rats were given 30% ethanol or water without ethanol treatment. Then, they were given 30% ethanol followed by FRB or FRS at concentrations of 15% or 30%. Our results indicate that the FRB might be more effective in lowering serum levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT) and alkaline phosphatase (ALP), malondialdehyde (MDA) levels in the serum and liver mitochondria, serum triglyceride levels and ALDH levels at a concentration of 15%, serum levels of lactate dehydrogenase (LDH), GSH levels at a concentration of 30% and MDA levels in the liver homogenate and microsome, and hepatic triglyceride levels at both concentrations as compared with the FRS. It can therefore be concluded that FRB might also be considered as an alternative to FRS in improving the AIHI.


2020 ◽  
Vol 1152 ◽  
pp. 122250
Author(s):  
Hanxu Wu ◽  
Chao Xu ◽  
Yifeng Gu ◽  
Shugao Yang ◽  
Yarong Wang ◽  
...  

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