Genetic polymorphisms of cytochrome P450 2D6 (CYP2D6) are associated with long term tramadol treatment-induced oxidative damage and hepatotoxicity

2018 ◽  
Vol 346 ◽  
pp. 37-44 ◽  
Author(s):  
Manar Hamed Arafa ◽  
Hebatallah Husseini Atteia
Keyword(s):  
Cytochrome P450 ◽  
Oxidative Damage ◽  
Genetic Polymorphisms ◽  
Cytochrome P450 2D6 ◽  
P450 2D6

scholarly journals Cytochrome P450 2D6 phenotype and genotype in hypertensive patients on long-term therapy with metoprolol

2013 ◽  
Vol 114 (04) ◽  
pp. 206-212
Author(s):  
J. Duricova ◽  
I. Perinova ◽  
N. Jurckova ◽  
I. Jeziskova ◽  
I. Kacirova ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Term Therapy ◽  
Cytochrome P450 2D6 ◽  
Hypertensive Patients ◽  
Long Term Therapy ◽  
P450 2D6

Probing Small-Molecule Binding to Cytochrome P450 2D6 and 2C9: An In Silico Protocol for Generating Toxicity Alerts

ChemMedChem ◽  
2010 ◽  
Vol 5 (12) ◽  
pp. 2088-2101 ◽  
Author(s):  
Gianluca Rossato ◽  
Beat Ernst ◽  
Martin Smiesko ◽  
Morena Spreafico ◽  
Angelo Vedani
Keyword(s):  
Cytochrome P450 ◽  
Small Molecule ◽  
In Silico ◽  
Cytochrome P450 2D6 ◽  
P450 2D6

From Genotype to Phenotype: Cytochrome P450 2D6-Mediated Drug Clearance in Humans

2017 ◽  
Vol 14 (3) ◽  
pp. 649-657 ◽  
Author(s):  
Jie Gao ◽  
Xin Tian ◽  
Jun Zhou ◽  
Ming-Zhu Cui ◽  
Hai-Feng Zhang ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Drug Clearance ◽  
Cytochrome P450 2D6 ◽  
P450 2D6
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