A novel and ultrasensitive sandwich-type electrochemical immunosensor based on delaminated MXene@AuNPs as signal amplification for prostate specific antigen (PSA) detection and immunosensor validation

Talanta ◽  
2020 ◽  
Vol 220 ◽  
pp. 121403 ◽  
Author(s):  
Hilal Medetalibeyoglu ◽  
Gül Kotan ◽  
Necip Atar ◽  
Mehmet Lütfi Yola
2018 ◽  
Vol 10 (40) ◽  
pp. 4917-4925 ◽  
Author(s):  
Li Liu ◽  
Guanhui Zhao ◽  
Xue Dong ◽  
Xuan Li ◽  
Qin Wei ◽  
...  

A sandwich-type electrochemical immunosensor was developed based on a multiple signal amplification strategy.


2020 ◽  
Vol 28 ◽  
Author(s):  
Hayati Filik ◽  
Asiye Aslıhan Avan ◽  
Mustafa Özyürek

: The prostate-specific antigen (PSA) has been considered a crucial serological marker for distinguishing prostate based cancer. This surveys recent progress in the construction of nanomaterial-based electrochemical immunosensors for a PSA. This review (from 2015 to 2020) reports the latest progress in PSA sensing based on the employ of different types of nanostructured materials. The most popular used nanostructured materials are metal, metal oxide, carbon-based nanomaterials, and their hybrid architectures utilized for distinct amplification protocols. In this review, the electrochemical immunosensors for prostate-specific antigen sensing are classified into three categories such as sandwich type@labeled, label free@nonlabeled and aptamer-based electrochemical immunosensor.


RSC Advances ◽  
2016 ◽  
Vol 6 (28) ◽  
pp. 23411-23419 ◽  
Author(s):  
Xiu Wang ◽  
Lei Shen ◽  
Wenping Deng ◽  
Mei Yan ◽  
Haiyun Liu ◽  
...  

We herein report the synthesis of MoS2 which was three-dimensional flower-like microspheres, and then the prepared GOx–AuPt and MoS2–luminol were applied in a sandwich-type ECL immunosensor for prostate-specific antigen detection.


2019 ◽  
Vol 11 (44) ◽  
pp. 5661-5672 ◽  
Author(s):  
Mina Shaban ◽  
Mohammad Hasanzadeh ◽  
Elham Solhi

A novel sandwich-type biosensor based on a signal amplification strategy of various nanocomposites was developed to monitor the prostate-specific antigen (PSA) in real samples.


RSC Advances ◽  
2015 ◽  
Vol 5 (90) ◽  
pp. 74046-74053 ◽  
Author(s):  
Long Yang ◽  
Hui Zhao ◽  
Guogang Deng ◽  
Xin Ran ◽  
Yucong Li ◽  
...  

The illustration for the constructed electrochemical immunosensor and the signal amplification strategy.


RSC Advances ◽  
2016 ◽  
Vol 6 (88) ◽  
pp. 84698-84704 ◽  
Author(s):  
Yanguang Chu ◽  
Huan Wang ◽  
Hongmin Ma ◽  
Dan Wu ◽  
Bin Du ◽  
...  

A new and facile sandwich-type electrochemical immunosensor is proposed for the ultrasensitive detection of prostate-specific antigen (PSA) based on Au nanoparticles (Au NPs) and palladium-doped cuprous oxide nanoparticles (Pd@Cu2O NPs).


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