All-in-one approaches for rapid and highly specific quantifcation of single nucleotide polymorphisms based on ligase detection reaction using molecular beacons as turn-on probes

Talanta ◽  
2021 ◽  
Vol 224 ◽  
pp. 121717
Author(s):  
Wancun Zhang ◽  
Kangbo Liu ◽  
Pin Zhang ◽  
Weyland Cheng ◽  
Yaodong Zhang ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphisms ◽  
Molecular Beacons ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Ligase Detection Reaction ◽  
Turn On

A turn-on dual emissive nucleobase sensitive to mismatches and duplex conformational changes

RSC Advances ◽  
2016 ◽  
Vol 6 (90) ◽  
pp. 87142-87146 ◽  
Author(s):  
Krishna Gavvala ◽  
Nicolas P. F. Barthes ◽  
Dominique Bonhomme ◽  
Anne Sophie Dabert-Gay ◽  
Delphine Debayle ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphisms ◽  
Conformational Changes ◽  
Dna Hybridization ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Turn On ◽  
Fluorescent Nucleoside

Herein, we demonstrate the on–off dual emissive behaviour of a fluorescent nucleoside sensitive towards DNA hybridization and conformational changes as well as detection of single nucleotide polymorphisms.

Enhanced discrimination of single nucleotide polymorphisms using 3′ nucleotide differences in ligase detection reaction probes

2010 ◽  
Vol 24 (6) ◽  
pp. 381-386 ◽  
Author(s):  
Masaru Asari ◽  
Tomohiro Omura ◽  
Chikatoshi Maseda ◽  
Hiroshi Shiono ◽  
Yoshikazu Tasaki ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphisms ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Ligase Detection Reaction

Short PNA molecular beacons for real-time PCR allelic discrimination of single nucleotide polymorphisms

2004 ◽  
Vol 18 (2) ◽  
pp. 117-122 ◽  
Author(s):  
Kenneth Petersen ◽  
Ulla Vogel ◽  
Eszter Rockenbauer ◽  
Kirsten Vang Nielsen ◽  
Steen Kølvraa ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphisms ◽  
Real Time ◽  
Real Time Pcr ◽  
Molecular Beacons ◽  
Nucleotide Polymorphisms ◽  
Allelic Discrimination ◽  
Single Nucleotide

Development of a simple method for the determination of single nucleotide polymorphisms

2010 ◽  
Vol 34 (8) ◽  
pp. S75-S75
Author(s):  
Weifeng Zhu ◽  
Zhuoqi Liu ◽  
Daya Luo ◽  
Xinyao Wu ◽  
Fusheng Wan
Keyword(s):  
Single Nucleotide Polymorphisms ◽  
Nucleotide Polymorphisms ◽  
Simple Method ◽  
Single Nucleotide
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