Unambiguous structure elucidation of the reaction products of 3-acyl-4-methoxy-1-methylquinolinones with hydroxylamine via NMR spectroscopy

Tetrahedron ◽  
2007 ◽  
Vol 63 (47) ◽  
pp. 11656-11660 ◽  
Author(s):  
Stefano Chimichi ◽  
Marco Boccalini ◽  
Alessandra Matteucci
Keyword(s):  
Nmr Spectroscopy ◽  
Structure Elucidation ◽  
Reaction Products

Structure elucidation by NMR spectroscopy: Assisted analysis from spectra to molecular structure

Planta Medica ◽  
2014 ◽  
Vol 80 (10) ◽  
Author(s):  
S Groscurth ◽  
T Kühn ◽  
P Kessler ◽  
V Rukachaisirikul
Keyword(s):  
Molecular Structure ◽  
Nmr Spectroscopy ◽  
Structure Elucidation ◽  
Assisted Analysis

Ionic liquids: green solvents and reactive compounds? Reaction of tri-n-butylmethylphosphonium dimethylphosphate with elemental sulfur

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Natalia Tarasova ◽  
Efrem Krivoborodov ◽  
Alexey Zanin ◽  
Yaroslav Mezhuev
Keyword(s):  
Ionic Liquids ◽  
Nmr Spectroscopy ◽  
Oxygen Atom ◽  
Elemental Sulfur ◽  
Green Solvents ◽  
Reaction Products ◽  
Mechanism Of Interaction

AbstractThe opening of the S8 ring with the formation of linear sulfur oligomers in the presence of tri-n-butylmethylphosphonium dimethylphosphate is shown. The reaction products are separated and characterized with 1H, 13C, 31P, 17O NMR spectroscopy, HD-MS, MALDI spectroscopy and XRD. It is shown that dimethylphosphate-anion is active in the reaction, and the addition of sulfur atoms occurs via the oxygen atom of dimethylphosphate-anion. It is found that a mixture of products is formed, which differ in the number of sulfur atoms in the chain. The assumptions were made about the mechanism of interaction of sulfur with tri-n-butylmethylphosphonium dimethylphosphate.

Pentacarbonylmanganese enolate and dienolate complexes. Preparative and mechanistic considerations

1990 ◽  
Vol 68 (3) ◽  
pp. 492-501 ◽  
Author(s):  
Andrew P. Masters ◽  
Ted S. Sorensen
Keyword(s):  
Nmr Spectroscopy ◽  
Nucleophilic Substitution ◽  
Reaction Products ◽  
Organic Products ◽  
Mechanism Of The Reaction ◽  
Model Reactions ◽  
Inorganic And Organic

Reactions of pentacarbonyl manganate anion with 4-halocrotonate esters or 2-halocarboxylate esters result in a complex set of inorganic and organic products, usually including the expected dienolate (or enolate) complexes. The reaction variables include the counterion, solvent, and halo group. The mechanism of the reaction has been investigated by conducting a thorough characterization of the reaction products under various conditions and also by carrying out model reactions. One can rationalize most of the non-organometallic products using either a radical or carbanion mechanism, but the latter seems to fit the available data better. Experimental procedures for optimizing the yield of the organometallic dienolate or enolate complexes have been worked out. Keywords: pentacarbonyl manganate, metalate nucleophilicity, enolate complex, nucleophilic substitution, 55Mn NMR spectroscopy.

scholarly journals Antiparasitic Metabolites from Hyptis brevipes, a Tacana Medicinal Plant

2019 ◽  
Vol 14 (1) ◽  
pp. 1934578X1901400 ◽  
Author(s):  
Ivan Limachi ◽  
Claudia Condo ◽  
Camila Palma ◽  
Nelida Nina ◽  
Efrain Salamanca ◽  
...  
Keyword(s):  
Plasmodium Falciparum ◽  
Nmr Spectroscopy ◽  
Medicinal Plants ◽  
Medicinal Plant ◽  
Trypanosoma Cruzi ◽  
Hela Cells ◽  
Giardia Lamblia ◽  
Structure Elucidation ◽  
Intestinal Parasites ◽  
Active Constituents

A bioassay screening against protozoa parasites of several Tacana medicinal plants gave Hyptis brevipes (Id'ene eidhue), traditionally used as decoction for intestinal parasites, as the most active extract. In this work we did a bioguided isolation of active constituents found in leaves. Structure elucidation was carried out by NMR spectroscopy and MS spectrometry analyses. Active constituents showed differentiated activity towards Giardia lamblia, Trypanosoma cruzi, several Leishmania strains, Plasmodium falciparum and cytotoxicity against HeLa cells. Brevipolide H (1) was the less cytotoxic and best antiparasitic, while the catechol derivative (2) the most active and cytotoxic.

scholarly journals Photochemische Reaktionen von Übergangsmetall-Olefin-Komplexen, V [1]. Die Umsetzung von Tricarbonyl-η-6.6-dimethylfulven-chrom(0) mit 7-Methyl- und 7-Methoxycycloheptatrien / Photochemical Reactions of Transition Metal Olefin Complexes, V [1]. The Reactions of Tricarbonyl-η-6,6-dimethylfulvene-chromium(0) with 7-Methyl- and 7-Methoxycycloheptatriene

1982 ◽  
Vol 37 (10) ◽  
pp. 1322-1326 ◽  
Author(s):  
Cornelius G. Kreiter ◽  
Hans Kurz
Keyword(s):  
Nmr Spectroscopy ◽  
Transition Metal ◽  
Column Chromatography ◽  
Room Temperature ◽  
Photochemical Reactions ◽  
Membered Ring ◽  
Reaction Products ◽  
Methyl Group

Abstract The stereochemistry of the photo reaction products of tricarbonyl-η-6,6-dimethyl-fulvene-chromium(O) (1) with 7-methyl-and 7-methoxycycloheptatriene was studied by NMR-spectroscopy. Both trienes add to 1, displace a CO ligand, and form substituted dicarbonyl-η3-2-cycloheptadienylene-η5-2-cyclopentadienylidene-propane-chromium(0) complexes. With C7H7CH3 only one isomer (3) is formed with the methyl-group in endo-position and the enyl system encompassing C(1′)-C(3′) of the seven membered ring. C7H7OCH3 yields 3 isomers which were separated by column chromatography. 5 has the same constitution as 3. The isomers 4 and 5 bear the OCH3-group in e^o-position. The enyl system of 4 is located on C(1′)-C(3′), that of 6 on C(3′)-C(5′). 6 rearranges at room temperature to 4.

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