scholarly journals Antitumor principles from Casearia sylvestris Sw.(Flacourtiaceae). Structure elucidation of new clerodane diterpenes by 2-D NMR spectroscopy.

1988 ◽  
Vol 36 (4) ◽  
pp. 1585-1588 ◽  
Author(s):  
Hideji Itokawa ◽  
Nobuo Totsuka ◽  
Koichi Takeya ◽  
Kinzo Watanabe ◽  
Etsuko Obata
Keyword(s):  
Nmr Spectroscopy ◽  
Structure Elucidation ◽  
Clerodane Diterpenes ◽  
Casearia Sylvestris

Structure elucidation by NMR spectroscopy: Assisted analysis from spectra to molecular structure

Planta Medica ◽  
2014 ◽  
Vol 80 (10) ◽  
Author(s):  
S Groscurth ◽  
T Kühn ◽  
P Kessler ◽  
V Rukachaisirikul
Keyword(s):  
Molecular Structure ◽  
Nmr Spectroscopy ◽  
Structure Elucidation ◽  
Assisted Analysis

scholarly journals Antiparasitic Metabolites from Hyptis brevipes, a Tacana Medicinal Plant

2019 ◽  
Vol 14 (1) ◽  
pp. 1934578X1901400 ◽  
Author(s):  
Ivan Limachi ◽  
Claudia Condo ◽  
Camila Palma ◽  
Nelida Nina ◽  
Efrain Salamanca ◽  
...  
Keyword(s):  
Plasmodium Falciparum ◽  
Nmr Spectroscopy ◽  
Medicinal Plants ◽  
Medicinal Plant ◽  
Trypanosoma Cruzi ◽  
Hela Cells ◽  
Giardia Lamblia ◽  
Structure Elucidation ◽  
Intestinal Parasites ◽  
Active Constituents

A bioassay screening against protozoa parasites of several Tacana medicinal plants gave Hyptis brevipes (Id'ene eidhue), traditionally used as decoction for intestinal parasites, as the most active extract. In this work we did a bioguided isolation of active constituents found in leaves. Structure elucidation was carried out by NMR spectroscopy and MS spectrometry analyses. Active constituents showed differentiated activity towards Giardia lamblia, Trypanosoma cruzi, several Leishmania strains, Plasmodium falciparum and cytotoxicity against HeLa cells. Brevipolide H (1) was the less cytotoxic and best antiparasitic, while the catechol derivative (2) the most active and cytotoxic.

scholarly journals Dithiosulfinates and Sulfoxides with Antifungal Activity from Bulbs of Allium sativum L. var. Voghiera

2018 ◽  
Vol 13 (9) ◽  
pp. 1934578X1801300
Author(s):  
Bruna de Falco ◽  
Giuliano Bonanomi ◽  
Virginia Lanzotti
Keyword(s):  
Antimicrobial Activity ◽  
Nmr Spectroscopy ◽  
Antifungal Activity ◽  
Botrytis Cinerea ◽  
Trichoderma Harzianum ◽  
Structure Elucidation ◽  
Allium Sativum ◽  
Fungal Species ◽  
Phytochemical Analysis ◽  
Spectroscopic Analyses

A bioassay guided phytochemical analysis of the bulbs of Allium sativum L. var. Voghiera, typical of Voghiera, Ferrara (Italy), allowed the isolation of six new sulfur compounds with dithiosulfinates and sulfoxides functionalities. Structure elucidation of the isolated compounds was carried out by spectroscopic analyses, including NMR spectroscopy and MS spectrometry. Compounds showed significant antimicrobial activity towards two fungal species, the air-borne pathogen Botrytis cinerea and the beneficial fungus Trichoderma harzianum.

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