Palladium-catalyzed one-pot Catellani reaction: An efficient synthesis of α-alkynyl aromatic ketones via ortho acylation and ipso alkynylation

Tetrahedron ◽  
2018 ◽  
Vol 74 (40) ◽  
pp. 5942-5949 ◽  
Author(s):  
Shao-Peng Yu ◽  
Yue Zhong ◽  
Ting Gu ◽  
Wen-Yu Wu ◽  
Tian-Yuan Fan ◽  
...  
Keyword(s):  
Efficient Synthesis ◽  
One Pot ◽  
Aromatic Ketones ◽  
Palladium Catalyzed

New one-pot synthesis of N-fused isoquinoline derivatives by palladium-catalyzed C–H arylation: potent inhibitors of nucleotide pyrophosphatase-1 and -3

2016 ◽  
Vol 14 (48) ◽  
pp. 11402-11414 ◽  
Author(s):  
Elina Ausekle ◽  
Syeda Abida Ejaz ◽  
Shafi Ullah Khan ◽  
Peter Ehlers ◽  
Alexander Villinger ◽  
...  
Keyword(s):  
Biological Evaluation ◽  
Efficient Synthesis ◽  
One Pot ◽  
One Pot Synthesis ◽  
Nucleotide Pyrophosphatase ◽  
Palladium Catalyzed ◽  
Synthesis Procedure ◽  
Isoquinoline Derivatives

An efficient synthesis procedure for N-fused isoquinolines from gem-difluoroalkenes is described, and biological evaluation of the sythesized products as inhibitors of h-NPP-1 and -3 is reported.

scholarly journals One-pot palladium-catalyzed synthesis of sulfonyl fluorides from aryl bromides

2017 ◽  
Vol 8 (2) ◽  
pp. 1233-1237 ◽  
Author(s):  
Alyn T. Davies ◽  
John M. Curto ◽  
Scott W. Bagley ◽  
Michael C. Willis
Keyword(s):  
Palladium Catalysis ◽  
Efficient Synthesis ◽  
One Pot ◽  
Aryl Bromides ◽  
Palladium Catalyzed

A mild, efficient synthesis of sulfonyl fluorides from aryl and heteroaryl bromides utilizing palladium catalysis is described.

Palladium-catalyzed synthesis of polysubstituted quinolines from 2-amino aromatic ketones and alkynes

2014 ◽  
Vol 50 (42) ◽  
pp. 5583-5585 ◽  
Author(s):  
Wang Zhou ◽  
Jianhua Lei
Keyword(s):  
One Pot ◽  
Aromatic Ketones ◽  
Palladium Catalyzed ◽  
First Time

A palladium-catalyzed one-pot method for the synthesis of quinolines from commercial or readily available 2-amino aromatic ketones and alkynes is reported for the first time.

Efficient Synthesis of 4H-3,1-Benzoxazine Derivatives via One-Pot Sequential Passerini-Azide/Palladium-Catalyzed Azide–Isocyanide Coupling/Cyclization Reaction

Synlett ◽  
2020 ◽  
Vol 31 (10) ◽  
pp. 1003-1006
Author(s):  
Jun Xiong ◽  
Qi-Xun Feng ◽  
Zhi-Ying Mu ◽  
Gang Yao ◽  
Jia-An Zhang ◽  
...  
Keyword(s):  
Cyclization Reaction ◽  
Efficient Synthesis ◽  
One Pot ◽  
Trimethylsilyl Azide ◽  
Palladium Catalyzed

A new, one-pot method for the synthesis of 4H-3,1-benzoxazine derivatives has been developed. The Passerini-azide reactions of 2-azidobenzaldehydes, trimethylsilyl azide, and isocyanides produced azide intermediate without separation, which then reacted with isocyanides to give 4H-3,1-benzoxazine derivatives via a tandem one-pot palladium-catalyzed azide–isocyanide coupling/cyclization reaction in moderate to good yields.

scholarly journals A novel and efficient synthesis of phenanthrene derivatives via palladium/norbornadiene-catalyzed domino one-pot reaction

2019 ◽  
Vol 15 ◽  
pp. 291-298 ◽  
Author(s):  
Yue Zhong ◽  
Wen-Yu Wu ◽  
Shao-Peng Yu ◽  
Tian-Yuan Fan ◽  
Hai-Tao Yu ◽  
...  
Keyword(s):  
Reaction Times ◽  
Diels Alder ◽  
Efficient Synthesis ◽  
One Pot ◽  
Aryl Iodides ◽  
Palladium Catalyzed

Herein we report a novel palladium-catalyzed reaction that results in phenanthrene derivatives using aryl iodides, ortho-bromobenzoyl chlorides and norbornadiene in one pot. This dramatic transformation undergoes ortho-C–H activation, decarbonylation and subsequent a retro-Diels–Alder process. Pleasantly, this protocol has a wider substrate range, shorter reaction times and higher yields of products than previously reported methods.

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