Pyrazole-tethered arylphosphine ligands for Suzuki reactions of aryl chlorides: how important is chelation?

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2005 ◽  
Vol 36 (33) ◽  
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Ping Ye ◽  
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ACS Omega ◽  
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Wan-Yun Hsu ◽  
Siou-Wei Liang ◽  
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...  

Successful Suzuki reactions of basic nitrogen containing aryl chlorides/bromides with arylboronic acids in water without added base, partially or entirely under acidic conditions.


2020 ◽  
Vol 17 (11) ◽  
pp. 857-863
Author(s):  
Mohammad Ali Nasseri ◽  
Seyyedeh Ameneh Alavi ◽  
Milad Kazemnejadi ◽  
Ali Allahresani

A convenient and efficient chiral CuFe2O4@SiO2-Mn(III) Ch.salen nanocatalyst has been developed for the C-N cross-coupling reactions of aryl halides/ phenylboronic acid with N-heterocyclic compounds in water and/or DMSO under mild conditions. The catalyst could be applied for the N-arylation of a variety of nitrogen-containing heterocycles with aryl chlorides, bromides, iodides and phenylboronic acid under mild conditions. Moderate to good yields were achieved for all substrates. The structure of catalyst was characterized using various techniques including FT-IR, FE-SEM, EDX, XRD, TEM and TGA. The catalyst can be simply recovered and reused for several times without significant loss of activity.


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