Humoral immune response in lactating dairy cows after repeated exposure to human chorionic gonadotropin

2012 ◽  
Vol 78 (1) ◽  
pp. 218-224 ◽  
Author(s):  
J.O. Giordano ◽  
M.C. Wiltbank ◽  
P.M. Fricke
1995 ◽  
Vol 41 (1) ◽  
pp. 32-34
Author(s):  
S. V. Shirshev

The functional activity of splenocytes of CBA mice was investigated in a syngeneic transfer system by the level of formation of antibody-producing cells (APC). Splenocytes were preincubated for 1 h in vitro with chorionic gonadotropin and type I recombinant interferons, as well as in hormonal-cytokine combinations. Chorionic gonadotropin in doses 10 and 50 MU/ml depressed APC formation, whereas alpha-interferon (250 MU/ml) stimulated it, and beta-interferon in the same concentration did not influence the level of humoral immune response. Chorionic gonadotropin, if added to splenocyte culture in combination with alpha-interferon, completely lost its immunodepressive properties. However, if together with alpha-interferon in a dose of 10 MU/ml it had a costimulating effect, in contrast to that, in combination with beta-interferon in the tested concentrations it was conducive to only a statistically reliable increase in the number of APC.


2020 ◽  
Vol 13 (1) ◽  
Author(s):  
Hee J. Kim ◽  
Aparna Krishnavajhala ◽  
Brittany A. Armstrong ◽  
Adalberto A. Pérez de León ◽  
Serhii Filatov ◽  
...  

2019 ◽  
Vol 102 (1) ◽  
pp. 846-856 ◽  
Author(s):  
A.M. Zolini ◽  
W.G. Ortiz ◽  
E. Estrada-Cortes ◽  
M.S. Ortega ◽  
S. Dikmen ◽  
...  

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