Ruthenium (II) complexes with N, O-chelating proline and threonine ligands cause selective cytotoxicity by the induction of genomic instability, cell cycle arrest and apoptosis in breast and prostate tumor cells

2020 ◽  
Vol 62 ◽  
pp. 104679
Author(s):  
Israel Higino de Sousa ◽  
Vanessa Niely Soares Campos ◽  
André Alvares Marques Vale ◽  
Vera Lucia Maciel-Silva ◽  
Celisnolia Moraes Leite ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Cell Cycle Arrest ◽  
Tumor Cells ◽  
Genomic Instability ◽  
Prostate Tumor ◽  
Selective Cytotoxicity ◽  
Cycle Arrest ◽  
Prostate Tumor Cells

β-Ionone Induces Cell Cycle Arrest and Apoptosis in Human Prostate Tumor Cells

2013 ◽  
Vol 65 (4) ◽  
pp. 600-610 ◽  
Author(s):  
Sheila Jones ◽  
Nicolle V. Fernandes ◽  
Hoda Yeganehjoo ◽  
Rajasekhar Katuru ◽  
Haibin Qu ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Cell Cycle Arrest ◽  
Tumor Cells ◽  
Prostate Tumor ◽  
Human Prostate ◽  
Cycle Arrest ◽  
Prostate Tumor Cells ◽  
Human Prostate Tumor

scholarly journals Cellular Senescence in Liver Disease and Regeneration

2021 ◽  
Author(s):  
Sofia Ferreira-Gonzalez ◽  
Daniel Rodrigo-Torres ◽  
Victoria L. Gadd ◽  
Stuart J. Forbes
Keyword(s):  
Cell Cycle ◽  
Liver Disease ◽  
Cell Cycle Arrest ◽  
Genomic Instability ◽  
Cellular Senescence ◽  
Cell Populations ◽  
Cycle Arrest ◽  
Relevant Role ◽  
Extent Of Damage

AbstractCellular senescence is an irreversible cell cycle arrest implemented by the cell as a result of stressful insults. Characterized by phenotypic alterations, including secretome changes and genomic instability, senescence is capable of exerting both detrimental and beneficial processes. Accumulating evidence has shown that cellular senescence plays a relevant role in the occurrence and development of liver disease, as a mechanism to contain damage and promote regeneration, but also characterizing the onset and correlating with the extent of damage. The evidence of senescent mechanisms acting on the cell populations of the liver will be described including the role of markers to detect cellular senescence. Overall, this review intends to summarize the role of senescence in liver homeostasis, injury, disease, and regeneration.

INI1 expression induces cell cycle arrest and markers of senescence in malignant rhabdoid tumor cells

2003 ◽  
Vol 194 (3) ◽  
pp. 303-313 ◽  
Author(s):  
Britta S. Reincke ◽  
Gary B. Rosson ◽  
Betty W. Oswald ◽  
Cynthia F. Wright
Keyword(s):  
Cell Cycle ◽  
Cell Cycle Arrest ◽  
Tumor Cells ◽  
Rhabdoid Tumor ◽  
Malignant Rhabdoid Tumor ◽  
Cycle Arrest

scholarly journals Tristetraprolin induces cell cycle arrest in breast tumor cells through targeting AP-1/c-Jun and NF-κB pathway

Oncotarget ◽  
2015 ◽  
Vol 6 (39) ◽  
pp. 41679-41691 ◽  
Author(s):  
Li Xu ◽  
Huan Ning ◽  
Ling Gu ◽  
Qinghong Wang ◽  
Wenbao Lu ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Cell Cycle Arrest ◽  
Tumor Cells ◽  
Breast Tumor ◽  
Breast Tumor Cells ◽  
Cycle Arrest

scholarly journals Loss of p53-mediated cell-cycle arrest, senescence and apoptosis promotes genomic instability and premature aging

Oncotarget ◽  
2016 ◽  
Vol 7 (11) ◽  
pp. 11838-11849 ◽  
Author(s):  
Tongyuan Li ◽  
Xiangyu Liu ◽  
Le Jiang ◽  
James Manfredi ◽  
Shan Zha ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Cell Cycle Arrest ◽  
Genomic Instability ◽  
Premature Aging ◽  
Cycle Arrest

scholarly journals Novel Tools to Analyze the Function of Salmonella Effectors Show That SvpB Ectopic Expression Induces Cell Cycle Arrest in Tumor Cells

PLoS ONE ◽  
2013 ◽  
Vol 8 (10) ◽  
pp. e78458 ◽  
Author(s):  
Beatriz Mesa-Pereira ◽  
Carlos Medina ◽  
Eva María Camacho ◽  
Amando Flores ◽  
Eduardo Santero
Keyword(s):  
Cell Cycle ◽  
Cell Cycle Arrest ◽  
Tumor Cells ◽  
Ectopic Expression ◽  
Cycle Arrest

ChemInform Abstract: A Novel Aminothiazole Derivative Induces Apoptosis and Cell Cycle Arrest in Tumor Cells.

ChemInform ◽  
2011 ◽  
Vol 42 (12) ◽  
pp. no-no
Author(s):  
Minghua Li ◽  
Changwon Oh ◽  
Jun Seok Park ◽  
Seung Wook Ham
Keyword(s):  
Cell Cycle ◽  
Cell Cycle Arrest ◽  
Tumor Cells ◽  
Cycle Arrest
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