Cystatin C as a Marker of Renal Function in Kidney Transplant Patients

2005 ◽  
Vol 37 (9) ◽  
pp. 3844-3847 ◽  
Author(s):  
A. Mendiluce ◽  
J. Bustamante ◽  
D. Martin ◽  
M. Santos ◽  
R. Bustamante ◽  
...  
Keyword(s):  
Renal Function ◽  
Kidney Transplant ◽  
Cystatin C ◽  
Transplant Patients ◽  
Kidney Transplant Patients

Serum cystatin C as an index of renal function in kidney transplant patients

2004 ◽  
Vol 36 (1) ◽  
pp. 99-101 ◽  
Author(s):  
S.H Akbas ◽  
A Yavuz ◽  
M Tuncer ◽  
C Ruhi ◽  
A Gurkan ◽  
...  
Keyword(s):  
Renal Function ◽  
Kidney Transplant ◽  
Cystatin C ◽  
Serum Cystatin C ◽  
Serum Cystatin ◽  
Transplant Patients ◽  
Kidney Transplant Patients

A Randomized Trial Comparing Renal Function in Older Kidney Transplant Patients Following Delayed Versus Immediate Tacrolimus Administration

2009 ◽  
Vol 88 (9) ◽  
pp. 1101-1108 ◽  
Author(s):  
Amado Andrés ◽  
Klemens Budde ◽  
Pierre-Alain Clavien ◽  
Thomas Becker ◽  
Michèle Kessler ◽  
...  
Keyword(s):  
Renal Function ◽  
Randomized Trial ◽  
Kidney Transplant ◽  
Transplant Patients ◽  
Kidney Transplant Patients

scholarly journals Randomized Phase 2b Trial of Tofacitinib (CP-690,550) in De Novo Kidney Transplant Patients: Efficacy, Renal Function and Safety at 1 Year

2012 ◽  
Vol 12 (9) ◽  
pp. 2446-2456 ◽  
Author(s):  
F. Vincenti ◽  
H. Tedesco Silva ◽  
S. Busque ◽  
P. O’Connell ◽  
J. Friedewald ◽  
...  
Keyword(s):  
Renal Function ◽  
Kidney Transplant ◽  
De Novo ◽  
Transplant Patients ◽  
Kidney Transplant Patients

scholarly journals Conversion from tacrolimus to belatacept improves renal function in kidney transplant patients with chronic vascular lesions in allograft biopsy

2018 ◽  
Vol 12 (4) ◽  
pp. 586-591 ◽  
Author(s):  
María José Pérez-Sáez ◽  
Bryant Yu ◽  
Audrey Uffing ◽  
Naoka Murakami ◽  
Thiago J Borges ◽  
...  
Keyword(s):  
Renal Function ◽  
Kidney Transplant ◽  
Estimated Glomerular Filtration Rate ◽  
Graft Loss ◽  
Vascular Lesions ◽  
First Year ◽  
Transplant Patients ◽  
Predicting Factors ◽  
Allograft Biopsy ◽  
Kidney Transplant Patients

AbstractBackgroundConversion from tacrolimus to belatacept has been shown to be beneficial for an increasing number of kidney transplant (KT) patients. Predicting factors for favorable outcomes are still unknown. We aimed to investigate whether histological vascular lesions at the time of conversion might correlate with greater improvement in renal function post-conversion.MethodsThe study was conducted on a retrospective cohort of 34 KT patients converted from tacrolimus to belatacept. All patients underwent an allograft biopsy prior to conversion. We analyzed the evolution of the estimated glomerular filtration rate (eGFR) at 3 and 12 months after conversion.ResultsMedian time to conversion was 6 (2–37.2) months post-transplant. About 52.9% of patients had moderate-to-severe chronic vascular lesions (cv2–3). We observed an increase in eGFR in the whole cohort from 35.4 to 41 mL/min/1.73 m2 at 3 months (P = 0.032) and 43.7 at 12 months (P = 0.013). Nine patients experienced acute rejection post-conversion, with one graft loss observed beyond the first year after conversion. Patients with cv2–3 had significant improvement in eGFR at 12 months (+8.6 mL/min/1.73 m2; 31.6 to 40.2 mL/min/1.73 m2; P = 0.047) compared with those without these lesions (+6.8 mL/min/1.73 m2; 40.9 to 47.7 mL/min/1.73 m2; P = 0.148).ConclusionsConversion from tacrolimus to belatacept has a beneficial effect in terms of renal function in KT patients. This benefit might be more significant in patients with cv in the biopsy.

Renal function to 5 years after late conversion of kidney transplant patients to everolimus: a randomized trial

2014 ◽  
Vol 28 (1) ◽  
pp. 115-123 ◽  
Author(s):  
Klemens Budde ◽  
Claudia Sommerer ◽  
Thomas Rath ◽  
Petra Reinke ◽  
Hermann Haller ◽  
...  
Keyword(s):  
Renal Function ◽  
Randomized Trial ◽  
Kidney Transplant ◽  
Transplant Patients ◽  
Kidney Transplant Patients

Influence of the CYP3A4/5 genetic score and ABCB1 polymorphisms on tacrolimus exposure and renal function in Brazilian kidney transplant patients

2016 ◽  
Vol 26 (10) ◽  
pp. 462-472 ◽  
Author(s):  
Fabiana D.V. Genvigir ◽  
Patricia C. Salgado ◽  
Claudia R. Felipe ◽  
Elena Y.F. Luo ◽  
Camila Alves ◽  
...  
Keyword(s):  
Renal Function ◽  
Kidney Transplant ◽  
Genetic Score ◽  
Transplant Patients ◽  
Kidney Transplant Patients
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