Serum cystatin C as an index of renal function in kidney transplant patients

2004 ◽  
Vol 36 (1) ◽  
pp. 99-101 ◽  
Author(s):  
S.H Akbas ◽  
A Yavuz ◽  
M Tuncer ◽  
C Ruhi ◽  
A Gurkan ◽  
...  
2020 ◽  
Vol 39 (4) ◽  
pp. S256
Author(s):  
A. Pinsino ◽  
D.L. Jennings ◽  
I. Mahoney ◽  
A. Sweat ◽  
A. Kim ◽  
...  

2005 ◽  
Vol 37 (9) ◽  
pp. 3844-3847 ◽  
Author(s):  
A. Mendiluce ◽  
J. Bustamante ◽  
D. Martin ◽  
M. Santos ◽  
R. Bustamante ◽  
...  

2009 ◽  
Vol 54 (2) ◽  
pp. 778-782 ◽  
Author(s):  
Akihiro Tanaka ◽  
Tetsuya Aiba ◽  
Takashi Otsuka ◽  
Katsuya Suemaru ◽  
Tatsuya Nishimiya ◽  
...  

ABSTRACT We determined the population pharmacokinetics of vancomycin (VAN) using the glomerular filtration rate (GFR) estimated from the serum cystatin C concentration. We examined the predictive performance of the trough serum VAN concentration for determination of the initial dose by using a new model for the analysis of the population pharmacokinetic parameters. Data for 86 patients were used to estimate the values of the population pharmacokinetic parameters. Analysis with a nonlinear mixed-effects modeling program was done by using a one-compartment model. Data for 78 patients were used to evaluate the predictive performance of the new model for the analysis of population pharmacokinetic parameters. The estimated GFR values determined by using Hoek's formula correlated linearly with VAN clearance (VAN clearance [ml/min] = 0.825 × GFR). The mean volume of distribution was 0.864 (liters/kg). The interindividual variability of VAN clearance was 19.8%. The accuracy of the prediction determined by use of the new model was statistically better than that determined by use of the Japanese nomogram-based model because the 95% confidence interval (−3.45 to −1.38) of the difference in each value of the mean absolute error (−2.41) did not include 0. Use of the serum cystatin C concentration as a marker of renal function for prediction of serum VAN concentrations may be useful.


2019 ◽  
Vol 1 (12) ◽  
pp. 623-627
Author(s):  
Masafumi Funamoto ◽  
Kana Shimizu ◽  
Yoichi Sunagawa ◽  
Yasufumi Katanasaka ◽  
Yusuke Miyazaki ◽  
...  

2012 ◽  
Vol 19 (7) ◽  
pp. 712-717 ◽  
Author(s):  
Hong-Xia Guo ◽  
Chen-Hong Wang ◽  
Zhi-Quan Li ◽  
Shi-Peng Gong ◽  
Zi-Qiong Zhou ◽  
...  

1998 ◽  
Vol 58 (7) ◽  
pp. 585-592 ◽  
Author(s):  
E. Randers ◽  
H. Kristensen ◽  
E.J Erlandsen ◽  
S Danielsen

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