In Vivo 31P MR Spectroscopy of Human Kidney Grafts Using the 2D-Chemical Shift Imaging Method

2011 ◽  
Vol 43 (5) ◽  
pp. 1570-1575 ◽  
Author(s):  
P. Vyhnanovská ◽  
M. Dezortová ◽  
V. Herynek ◽  
P. Táborský ◽  
O. Viklický ◽  
...  
2010 ◽  
Vol 64 (6) ◽  
pp. 1542-1556 ◽  
Author(s):  
Ovidiu C. Andronesi ◽  
Saadallah Ramadan ◽  
Carolyn E. Mountford ◽  
A.Gregory Sorensen

1992 ◽  
Vol 33 (3) ◽  
pp. 258-261 ◽  
Author(s):  
M. Harada ◽  
H. Nishitani ◽  
K. Koga ◽  
I. Miura ◽  
R. Kido

The metabolism of 5-fluorotryptophan in rat liver was examined by in vivo 19F MR spectroscopy. After i.v. injection of 200 mg/kg b.w. of 5-fluorotryptophan the substance was noted immediately as a strong peak, which decreased gradually. Another peak appeared about 40 min after the injection. The chemical shift value of this peak was 1.6 ppm from that of 5-fluorotryptophan. Kynurenine is known to be a major metabolite of tryptophan in the liver. We synthesized 5-fluorokynurenine from 5-fluorotryptophan by ozonolysis. The chemical shift value of 5-fluorokynurenine was confirmed to be coincident with that of the metabolite peak. This strongly suggests that the metabolite peak of 5-fluorotryptophan observed in this study was the 5-fluorokyrurenine signal. We also applied this method for the CCl4-injured liver. In the liver injury group, the metabolite peak appeared slowly and the intensity was low compared to that of the normal group, though the peak of 5-fluorotryptophan decreased similarly as in the normal liver. These results suggest that the decrease of 5-fluorotryptophan is due mainly to the renal excretion, as the injured liver could not metabolize 5-fluorotryptophan.


2010 ◽  
Vol 204 (2) ◽  
pp. 340-345 ◽  
Author(s):  
Dirk Mayer ◽  
Yi-Fen Yen ◽  
Yakir S. Levin ◽  
James Tropp ◽  
Adolf Pfefferbaum ◽  
...  

1992 ◽  
Vol 23 (1) ◽  
pp. 77-88 ◽  
Author(s):  
Susan. J. Kohler ◽  
Nancy H. Kolodny ◽  
Ann C. Celi ◽  
Tracey A. Burr ◽  
David Weinberg ◽  
...  

1989 ◽  
Vol 10 (2) ◽  
pp. 282-287 ◽  
Author(s):  
D. N. Guilfoyle ◽  
A. Blamire ◽  
B. Chapman ◽  
R. J. Ordine ◽  
P. Mansfield

1984 ◽  
Vol 19 (5) ◽  
pp. S42
Author(s):  
R. J. Herfkens ◽  
G. A. Johnson ◽  
G. Glover

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