Study 2: tacrolimus as secondary intervention versus continuation of cyclosporine in patients at risk for chronic renal allograft failure results in improved renal function, decreased cardiovascular risk, and no increased risk for diabetes

2003 ◽  
Vol 17 (4) ◽  
pp. S48
Author(s):  
Thomas H. Waid
Keyword(s):  
At Risk ◽  
Renal Function ◽  
Cardiovascular Risk ◽  
Renal Allograft ◽  
Secondary Intervention ◽  
Allograft Failure ◽  
Increased Risk ◽  
Patients At Risk ◽  
Renal Allograft Failure

Conversion From Cyclosporine to Tacrolimus in Patients at Risk for Chronic Renal Allograft Failure: 60-Month Results of the CRAF Study

2008 ◽  
Vol 85 (9) ◽  
pp. 1261-1269 ◽  
Author(s):  
Fuad S. Shihab ◽  
Thomas H. Waid ◽  
David J. Conti ◽  
Harold Yang ◽  
Michael J. Holman ◽  
...  
Keyword(s):  
At Risk ◽  
Renal Allograft ◽  
Allograft Failure ◽  
Patients At Risk ◽  
Renal Allograft Failure

scholarly journals The Association between Peri-Transplant RBC Transfusion and Graft Failure after Kidney Transplantation: A Nationwide Cohort Study

2021 ◽  
Vol 10 (16) ◽  
pp. 3750
Author(s):  
Kyungho Lee ◽  
Seohee Lee ◽  
Eun Jin Jang ◽  
Ga Hee Kim ◽  
Seokha Yoo ◽  
...  
Keyword(s):  
Kidney Transplantation ◽  
Failure Rate ◽  
Graft Failure ◽  
Renal Allograft ◽  
Patient Survival ◽  
Overall Survival Rate ◽  
Allograft Failure ◽  
Increased Risk ◽  
Renal Allograft Failure ◽  
Rbc Transfusion

Background: Patients undergoing kidney transplantation (KT) often receive red blood cell (RBC) transfusion during admission for KT which may increase the risk of allosensitization. The association between peri-transplant RBC transfusion and graft survival was evaluated using a nationwide cohort. Methods: This retrospective study analyzed 13,871 patients who underwent KT in Korea between 2007 and 2015. The outcomes were graft failure rate and overall patient survival depending on the amount of RBC transfusion. Results: The overall graft failure rate was 15.5%. Compared to the graft failure rate of 13.5% in the no transfusion group, the graft failure rate was 15.4% in the 1–2 units group (sHR 1.06 (95% CI 0.97–1.17), p = 0.216), 21.4% in the 3–5 units group (sHR 1.39 (1.21–1.61), p < 0.001), and 35.3% in the 6 or more units group (sHR 2.20 (1.70–2.85), p < 0.001). The overall survival rate was 97.5% in the no transfusion group, compared to 95.9% in the 1–2 units group (HR 1.50 (1.22–1.83), p < 0.001), 92.0% in the 3–5 units group (HR 2.43 (1.87–3.15), p < 0.001), and 67.5% in the 6 or more units group (HR 6.81 (5.03–9.22), p < 0.001). Conclusions: Peri-transplant RBC transfusion was independently associated with the increased risk of renal allograft failure and death in KT patients.

scholarly journals High Pretransplant Serum Levels of CXCL10/IP-10 Are Related to Increased Risk of Renal Allograft Failure

2004 ◽  
Vol 4 (9) ◽  
pp. 1466-1474 ◽  
Author(s):  
Mario Rotondi ◽  
Alberto Rosati ◽  
Andrea Buonamano ◽  
Laura Lasagni ◽  
Elena Lazzeri ◽  
...  
Keyword(s):  
Renal Allograft ◽  
Serum Levels ◽  
Allograft Failure ◽  
Increased Risk ◽  
Renal Allograft Failure

scholarly journals Plasma-cell-rich infiltrates in paediatric renal transplant biopsies are associated with increased risk of renal allograft failure

2016 ◽  
Vol 32 (4) ◽  
pp. 679-684 ◽  
Author(s):  
Stephanie Dufek ◽  
Azaz Khalil ◽  
Nizam Mamode ◽  
Neil J. Sebire ◽  
Stephen D. Marks
Keyword(s):  
Renal Transplant ◽  
Plasma Cell ◽  
Renal Allograft ◽  
Allograft Failure ◽  
Increased Risk ◽  
Renal Allograft Failure

THE ROLE OF AZATHIOPRINE REDUCTION IN LATE RENAL ALLOGRAFT FAILURE

1985 ◽  
Vol 39 (2) ◽  
pp. 147-150 ◽  
Author(s):  
P. S. PARFREY ◽  
T. A. HUTCHINSON ◽  
R. P. LOWRY ◽  
J. KNAACK ◽  
R. D. GUTTMANN
Keyword(s):  
Renal Allograft ◽  
Allograft Failure ◽  
Renal Allograft Failure
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