scholarly journals Monitoring and Staging Abdominal Aortic Aneurysm Disease With Pulse Wave Imaging

2014 ◽  
Vol 40 (10) ◽  
pp. 2404-2414 ◽  
Author(s):  
Sacha D. Nandlall ◽  
Monica P. Goldklang ◽  
Aubrey Kalashian ◽  
Nida A. Dangra ◽  
Jeanine M. D’Armiento ◽  
...  
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Pulse Wave ◽  
Abdominal Aortic ◽  
Wave Imaging

Abdominal aortic aneurysm, arterial stiffening and the role of the intraluminal thrombus

VASA ◽  
2015 ◽  
Vol 44 (5) ◽  
pp. 349-353 ◽  
Author(s):  
Maria Lyck Hansen ◽  
Marie Dahl Thomsen ◽  
Lars Melholt Rasmussen ◽  
Jes S. Lindholt
Keyword(s):  
Blood Pressure ◽  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Pulse Wave ◽  
Augmentation Index ◽  
Smoking Status ◽  
Intraluminal Thrombus ◽  
Abdominal Aortic ◽  
Male Patients

Abstract. Summary: Background: Measures of arterial stiffness could be affected by the presence of abdominal aortic aneurysm (AAA) and especially an intraluminal thrombus (ILT). We, therefore, sought to study this possible connection by measuring pulse wave velocity (PWV) and pulse wave analysis (PWA) including augmentation index adjusted to heart rate 75(Aix75) in patients with AAA +/- ILT. Patients and methods: PWV and PWA were measured in male patients with AAA from an ongoing Danish AAA screening trial. Information on blood pressure, medications, BMI and smoking status was obtained at inclusion. Results: In total, 157 patients were included. Mean age was 73 years. Mean AAA size was 42.2 mm. Fifty-six of the patients had an intraluminal thrombus, and patients with AAA and ILT had a significantly higher Aix75 than patients with AAA but without ILT (Mean = 28.3 ± 1.4 SEM vs. 24.9 ± 0.81, p=0.027), a difference that was also significant when adjusting for AAA size, blood pressure and age. There was no difference in PWV between the groups. Conclusions: Haemodynamic properties of the aorta are affected by the presence of ILT in patients with AAA that is not explained by aortic size. Alternatively, these findings could be explained by associations between ILT and properties of the left ventricle.

scholarly journals FSI Simulations of Pulse Wave Propagation in Human Abdominal Aortic Aneurysm: The Effects of Sac Geometry and Stiffness

2016 ◽  
Vol 7 ◽  
pp. BECB.S40094 ◽  
Author(s):  
Han Li ◽  
Kexin Lin ◽  
Danial Shahmirzadi
Keyword(s):  
Wave Propagation ◽  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Pulse Wave ◽  
Fluid Velocity ◽  
In Vivo Studies ◽  
Pulse Wave Propagation ◽  
Wall Displacement ◽  
Abdominal Aortic ◽  
Pulse Waves

This study aims to quantify the effects of geometry and stiffness of aneurysms on the pulse wave velocity (PWV) and propagation in fluid-solid interaction (FSI) simulations of arterial pulsatile flow. Spatiotemporal maps of both the wall displacement and fluid velocity were generated in order to obtain the pulse wave propagation through fluid and solid media, and to examine the interactions between the two waves. The results indicate that the presence of abdominal aortic aneurysm (AAA) sac and variations in the sac modulus affect the propagation of the pulse waves both qualitatively (eg, patterns of change of forward and reflective waves) and quantitatively (eg, decreasing of PWV within the sac and its increase beyond the sac as the sac stiffness increases). The sac region is particularly identified on the spatiotemporal maps with a region of disruption in the wave propagation with multiple short-traveling forward/reflected waves, which is caused by the change in boundary conditions within the saccular region. The change in sac stiffness, however, is more pronounced on the wall displacement spatiotemporal maps compared to those of fluid velocity. We conclude that the existence of the sac can be identified based on the solid and fluid pulse waves, while the sac properties can also be estimated. This study demonstrates the initial findings in numerical simulations of FSI dynamics during arterial pulsations that can be used as reference for experimental and in vivo studies. Future studies are needed to demonstrate the feasibility of the method in identifying very mild sacs, which cannot be detected from medical imaging, where the material property degradation exists under early disease initiation.

Measures of carotid–femoral pulse wave velocity and augmentation index are not reliable in patients with abdominal aortic aneurysm

2013 ◽  
Vol 31 (9) ◽  
pp. 1853-1860 ◽  
Author(s):  
Ching Wei Lee ◽  
Shih Hsien Sung ◽  
Chun Ku Chen ◽  
I Ming Chen ◽  
Hao Min Cheng ◽  
...  
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Pulse Wave ◽  
Augmentation Index ◽  
Abdominal Aortic

scholarly journals Evaluation of Aortic Stiffness (Aortic Pulse–Wave Velocity) Before and After Elective Abdominal Aortic Aneurysm Repair Procedures: A Pilot Study#

2009 ◽  
Vol 3 (1) ◽  
pp. 173-175 ◽  
Author(s):  
Kosmas I Paraskevas ◽  
Nikolaos Bessias ◽  
Chrysovalantis Psathas ◽  
Konstantinos Akridas ◽  
Theodoros Dragios ◽  
...  
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Pulse Wave ◽  
Rank Correlation ◽  
Abdominal Aortic Aneurysm Repair ◽  
Rupture Risk ◽  
Abdominal Aortic ◽  
Before And After

Background: The main clinical criterion for abdominal aortic aneurysm (AAA) repair operations is an AAA diameter ≥5.5 cm. When AAAs increase in size, specific changes occur in the mechanical properties of the aortic wall. Pulse-wave velocity (PWV) has been used as an indicator of vascular stiffness. A low PWV may predict AAA rupture risk and is an early predictor of cardiovascular mortality. Methods: We investigated the prognostic value of PWV before and after elective AAA repair procedures. Twenty four patients scheduled for an open AAA repair underwent a preoperative carotid-femoral aortic PWV measurement. A second aortic PWV measurement was carried out 6 months postoperatively. Results: The mean aortic PWV increased from 7.84 ± 1.85 preoperatively to 10.08 ± 1.57 m/sec 6 months postoperatively (mean change: 2.25; 95% confidence interval 1.4 to 3.1 m/sec; p<0.0001). The preprocedural PWV measurement did not correlate with AAA diameter (Spearman’s rank correlation coefficient ρ=0.12; p=0.59). Conclusions: Whether the increase in aortic PWV postoperatively suggests a decreased cardiovascular risk following AAA repair remains to be established. Aortic PWV should also be investigated as an adjunct tool for assessing AAA rupture risk.

scholarly journals Pulse Wave Velocity as a Measure of Arterial Stiffness in Patients with Abdominal Aortic Aneurysm: A Systematic Review and Meta-Analysis

2021 ◽  
Author(s):  
Xiaofeng Chen ◽  
Hongliang Zhang ◽  
Yangyang Shi ◽  
Tingting Chen ◽  
Yang Zhang ◽  
...  
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Arterial Stiffness ◽  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Subgroup Analysis ◽  
Pulse Wave ◽  
Meta Analysis ◽  
Healthy Controls ◽  
Abdominal Aortic

Abstract Background and objective: The relationship between pulse wave velocity (PWV) levels and abdominal aortic aneurysm (AAA) remains controversial. A meta-analysis was performed to establish whether vascular pulse wave velocity (PWV) as a measure of arterial stiffness is different in patients with abdominal aortic aneurysms and controls. Methods Pubmed, Embase, Cochrane and China National Knowledge Infrastructure (CNKI) were used for the meta-analysis with articles up to January 1, 2021. To compare PWV levels between AAA patients and healthy controls, pooled weighted mean difference (WMD) and its 95% confidence interval (Cl) were calculated. Subgroup analysis and funnel plots are used to assess the quality of the combined results to ensure a normal distribution of data with minimal bias. Study quality for eligible studies was assessed using the Agency For Health Care Research and Quality (AHRQ) inventory tool. Results Nine cross-sectional studies, which included 439 abdominal aortic aneurysm cases and 382 healthy subjects, met inclusion criteria and were eligible for meta-analysis. We found that PWV levels were significantly higher [WMD(95%Cl): 2.36(2.02,2.70)] in AAA patients than healthy controls. After subgroup analysis, it was found that age, sex, smoking and hypertension had significant effects on the PWV levels. The normal distribution of the Funnel plot analysis suggests a low risk for publication bias. Conclusion PWV levels were elevated in patients with AAA compared to healthy controls, with the effect on PWV altered by age, sex, smoking and hypertension. Our study suggests that abdominal aortic aneurysm is related to increased arterial stiffness.

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