scholarly journals The insertion domain of the duck hepatitis B virus core protein plays a role in nucleocapsid assembly

Virology ◽  
2006 ◽  
Vol 353 (2) ◽  
pp. 443-450 ◽  
Author(s):  
Haitao Guo ◽  
Carol E. Aldrich ◽  
Jeffry Saputelli ◽  
Chunxiao Xu ◽  
William S. Mason
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Core Protein ◽  
Duck Hepatitis B Virus ◽  
Virus Core ◽  
Duck Hepatitis ◽  
B Virus

scholarly journals Dominant negative mutants of the duck hepatitis B virus core protein interfere with RNA pregenome packaging and viral DNA synthesis

Hepatology ◽  
1999 ◽  
Vol 30 (1) ◽  
pp. 308-315 ◽  
Author(s):  
Fritz von Weizsäcker ◽  
Josef Köck ◽  
Stefan Wieland ◽  
Wolf-Bernhard Offensperger ◽  
Hubert E. Blum
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Dna Synthesis ◽  
Core Protein ◽  
Dominant Negative ◽  
Viral Dna ◽  
Duck Hepatitis B Virus ◽  
Virus Core ◽  
Duck Hepatitis ◽  
B Virus

scholarly journals Central Role of a Serine Phosphorylation Site within Duck Hepatitis B Virus Core Protein for Capsid Trafficking and Genome Release

2003 ◽  
Vol 278 (30) ◽  
pp. 28123-28129 ◽  
Author(s):  
Josef Köck ◽  
Michael Kann ◽  
Gerhard Pütz ◽  
Hubert E. Blum ◽  
Fritz von Weizsäcker
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Core Protein ◽  
Phosphorylation Site ◽  
Serine Phosphorylation ◽  
Duck Hepatitis B Virus ◽  
Virus Core ◽  
Duck Hepatitis ◽  
B Virus

scholarly journals Monoclonal Antibodies Providing Topological Information on the Duck Hepatitis B Virus Core Protein and Avihepadnaviral Nucleocapsid Structure

2007 ◽  
Vol 81 (23) ◽  
pp. 13230-13234 ◽  
Author(s):  
Jolanta Vorreiter ◽  
Immanuel Leifer ◽  
Christine Rösler ◽  
Ludmila Jackevica ◽  
Paul Pumpens ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Structural Model ◽  
Core Protein ◽  
Duck Hepatitis B Virus ◽  
Virus Core ◽  
Duck Hepatitis ◽  
B Virus ◽  
High Resolution Structure

ABSTRACT The icosahedral capsid of duck hepatitis B virus (DHBV) is formed by a single core protein species (DHBc). DHBc is much larger than HBc from human HBV, and no high-resolution structure is available. In an accompanying study (M. Nassal, I. Leifer, I. Wingert, K. Dallmeier, S. Prinz, and J. Vorreiter, J. Virol. 81:13218-13229, 2007), we used extensive mutagenesis to derive a structural model for DHBc. For independent validation, we here mapped the epitopes of seven anti-DHBc monoclonal antibodies. Using numerous recombinant DHBc proteins and authentic nucleocapsids from different avihepadnaviruses as test antigens, plus a panel of complementary assays, particle-specific and exposed plus buried linear epitopes were revealed. These data fully support key features of the model.

scholarly journals Cis -preferential recruitment of duck hepatitis B virus core protein to the RNA/polymerase preassembly complex

Hepatology ◽  
2002 ◽  
Vol 35 (1) ◽  
pp. 209-216 ◽  
Author(s):  
Fritz von Weizsäcker ◽  
Josef Köck ◽  
Stefan Wieland ◽  
Jürgen Beck ◽  
Michael Nassal ◽  
...  
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Rna Polymerase ◽  
Core Protein ◽  
Duck Hepatitis B Virus ◽  
Virus Core ◽  
Duck Hepatitis ◽  
B Virus
Sign in / Sign up

Export Citation Format

Share Document