See more with C-MORE: Addressing the need of robust cardiomyocyte morphological assessment

This paper describes morphological and cytochemistry changes of endomyocardial biopsy in 94 patients. The samples of myoicardium were taken from 32 patients with dilated cardiomyopathy, and sdudied with light and electron microscop. The cytochemical studies in some of these patients were performed at histological and ultrastructure level. This paper also reported the result of myocardial biopsy in 33 patients with serious dysrythmia.The result of this controlled study indicates that morphological assessment in both cardiomyopathy and congenital or rheumatic heart diseases showed no special changes. In patients of dilated cardiomyopathy, the decreased activity of myosin ATPase was secondary to cardial failure. The change of succinate dehydrogenase (SDHase) was not significant with light microscopy. But ultrastructural localization of SDHase activity is valuable. Its activity was found to be localized in endomembrane and ridge of the mitochondria, the activity of this enzyme was decrease, normal, or increase. SDHase activity was more intense in cardial myocytes well-functioning, or ultrastructurally well preserved hearts.

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Interaction of the Wallstent With the Coronary Artery During a Longterm Follow-up: Morphological Assessment by Serial Intravascular Ultrasound With a Motorized Pullback System

Journal of the American College of Cardiology ◽

10.1016/s0735-1097(97)88152-1 ◽

1998 ◽

Vol 31 (2) ◽

pp. 494A ◽

Cited By ~ 1

Author(s):

A König

Keyword(s):

Coronary Artery ◽

Intravascular Ultrasound ◽

Morphological Assessment

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Two-dimensional-Wilkins and real-time transesophageal three-dimensional scoring systems: Which one is preferred to mitral valve morphological assessment?

Asian Cardiovascular and Thoracic Annals ◽

10.1177/02184923211030424 ◽

2021 ◽

pp. 021849232110304

Author(s):

Mehrnoush Toufan ◽

Zahra Jabbary ◽

Naser Khezerlou aghdam

Keyword(s):

Mitral Valve ◽

Transthoracic Echocardiography ◽

Scoring System ◽

Three Dimensional ◽

Scoring Systems ◽

Two Dimensional ◽

Mitral Valve Area ◽

2D And 3D ◽

Morphological Assessment ◽

Valve Area

Background To quantify valvular morphological assessment, some two-dimensional (2D) and three-dimensional (3D) scoring systems have been developed to target the patients for balloon mitral valvuloplasty; however, each scoring system has some potential limitations. To achieve the best scoring system with the most features and the least restrictions, it is necessary to check the degree of overlap of these systems. Also the factors related to the accuracy of these systems should be studied. We aimed to determine the correlation between the 2D Wilkins and real-time transesophageal three-dimensional (RT3D-TEE) scoring systems. Methods This cross-sectional study was performed on 156 patients with moderate to severe mitral stenosis who were candidates for percutaneous balloon valvuloplasty. To morphologic assessment of mitral valve, patients were examined by 2D-transthoracic echocardiography and RT3D-TEE techniques on the same day. Results A strong association was found between total Wilkins and total RT3D-TEE scores (r = 0.809, p < 0.001). The mean mitral valve area assessed by the 2D and 3D was 1.07 ± 0.25 and 1.03 ± 0.26, respectively, indicating a mean difference of 0.037 cm2 (p = 0.001). We found a strong correlation between the values of mitral valve area assessed by 2D and 3D techniques (r = 0.846, p < 0.001). Conclusion There is a high correlation between the two scoring systems in terms of evaluating dominant morphological features. Partially, mitral valve area overestimation in the 2D-transthoracic echocardiography and its inability to assess commissural involvement as well as its dependence on patient age were exceptions in this study.

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