Hippocampal injury and learning deficits following non-convulsive status epilepticus in periadolescent rats

2021 ◽  
Vol 125 ◽  
pp. 108415
Author(s):  
Rita Asdikian ◽  
Helene Hajjar ◽  
Sana Alturk ◽  
Jean-Pierre Asdikian ◽  
Fatima Jaafar ◽  
...  
2021 ◽  
Vol 26 (1) ◽  
pp. 50-57
Author(s):  
Kyle C McKenzie ◽  
Cecil D Hahn ◽  
Jeremy N Friedman

Abstract This guideline addresses the emergency management of convulsive status epilepticus (CSE) in children and infants older than 1 month of age. It replaces a previous position statement from 2011, and includes a new treatment algorithm and table of recommended medications based on new evidence and reflecting the evolution of clinical practice over the past several years. This statement emphasizes the importance of timely pharmacological management of CSE, and includes some guidance for diagnostic approach and supportive care.


2021 ◽  
pp. 155005942199171
Author(s):  
Adriana Gómez Domínguez ◽  
Raidili C. Mateo Montero ◽  
Alba Díaz Cid ◽  
Antonio J. P. Mazarro ◽  
Ignacio R. Bailly-Bailliere ◽  
...  

Introduction. Non-convulsive status epilepticus (NCSE) has been traditionally a challenging electroencephalographic (EEG) diagnosis. For this reason, Salzburg consensus criteria (SCC) have been proposed to facilitate correct diagnosis. Methods. We retrospectively reanalyzed 41 cases referred to our department (from 2016 to 2018) under the suspicion of NCSE. In this study, we compared the original description (standard criteria) versus the updated description (SCC) of the same EEG. Results. Originally, 15 patients were diagnosed as NCSE (37%) and 26 patients as no NCSE (63%), using the standard criteria. Then, we analyzed EEGs according to the SCC, which led to the following results: 9 patients fulfilled the criteria for definite NCSE (22%), 20 patients were diagnosed as possible NCSE (49%) and 12 patients were diagnosed as no NCSE (29%). Subsequently, when we analyze the outcome of possible NCSE cases, we note that 50% of these patients presented mild-poor outcome (neurological deficits, deceased). Indeed, we observed worse outcomes in patients previously diagnosed as no NCSE and untreated, specifically post-anoxic cases. Conclusions. Salzburg criteria seem to be a useful tool to support NCSE diagnosis, introducing the category of possible NCSE. In our study, we observed that it contributes to improving the prognosis and management of the patients. However, more prospective studies are needed to demonstrate the accuracy of SCC.


Seizure ◽  
2021 ◽  
Vol 88 ◽  
pp. 29-35
Author(s):  
Sinead Zeidan ◽  
Benjamin Rohaut ◽  
Hervé Outin ◽  
Francis Bolgert ◽  
Marion Houot ◽  
...  

Seizure ◽  
2021 ◽  
Author(s):  
Sara Parreira ◽  
Luís Abreu ◽  
Ana Franco ◽  
Carla Bentes ◽  
Ana Rita Peralta

Neurology ◽  
2015 ◽  
Vol 84 (18) ◽  
pp. 1838-1845 ◽  
Author(s):  
S. M. Kariuki ◽  
A. Kakooza-Mwesige ◽  
R. G. Wagner ◽  
E. Chengo ◽  
S. White ◽  
...  

Seizure ◽  
2016 ◽  
Vol 36 ◽  
pp. 31-35 ◽  
Author(s):  
Lokesh Lingappa ◽  
Ramesh Konanki ◽  
Ravi Patel ◽  
Sudhindra Vooturi ◽  
Sita Jayalakshmi

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