Clinical impact of low-volume lymph node metastases in early-stage cervical cancer: A comprehensive meta-analysis

2021 ◽  
Author(s):  
Benedetta Guani ◽  
Katia Mahiou ◽  
Adrien Crestani ◽  
David Cibula ◽  
Alessandro Buda ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Lymph Node ◽  
Lymph Node Metastases ◽  
Early Stage ◽  
Meta Analysis ◽  
Clinical Impact ◽  
Early Stage Cervical Cancer ◽  
Node Metastases ◽  
Low Volume

High Number of Intraepithelial CD8+ Tumor-Infiltrating Lymphocytes Is Associated with the Absence of Lymph Node Metastases in Patients with Large Early-Stage Cervical Cancer

2007 ◽  
Vol 67 (1) ◽  
pp. 354-361 ◽  
Author(s):  
Sytse J. Piersma ◽  
Ekaterina S. Jordanova ◽  
Mariëtte I.E. van Poelgeest ◽  
Kitty M.C. Kwappenberg ◽  
Jeanette M. van der Hulst ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Lymph Node ◽  
Lymph Node Metastases ◽  
Early Stage ◽  
Tumor Infiltrating Lymphocytes ◽  
Early Stage Cervical Cancer ◽  
Node Metastases ◽  
Infiltrating Lymphocytes

Surgical treatment of lymph node metastases in stage IB cervical cancer: The laterally extended parametrectomy (LEP) procedure

2003 ◽  
Vol 13 (5) ◽  
pp. 647-651 ◽  
Author(s):  
L. Ungar ◽  
L. Palfalvi
Keyword(s):  
Cervical Cancer ◽  
Lymph Node ◽  
Cancer Patients ◽  
Lymph Node Metastases ◽  
Early Stage ◽  
Pelvic Lymph Node ◽  
Significant Treatment ◽  
Stage Ib ◽  
Early Stage Cervical Cancer ◽  
Node Metastases

A surgical method has been introduced for the treatment of early stage cervical cancer patients with pelvic lymph node metastases. The procedure was used without any adjuvant treatment in 31 stage IB cervical cancer patients, where pelvic lymph node metastases were proven by intraoperative histology. Two patients were lost for follow-up. Twenty-nine patients were followed up for 24–105 months (mean 60 months). Twenty-five of 29 patients were alive and disease-free at the end of the study period. Kaplan-Meier 5 years cumulative proportion survival was 85% (SE 7%). Complications in four cases (16%) necessitated a second operation. One patient developed treatment-refractory grade II incontinence. All but the one incontinent patient are alive without significant treatment related symptoms. The results suggest that pelvic lymph node metastases can be cured by surgery alone. The LEP procedure seems to be a treatment alternative to chemoradiotherapy for early stage cervical cancer patients with pelvic lymph node metastases.

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