Engineering Halomonas bluephagenesis for L-Threonine production

2020 ◽  
Vol 60 ◽  
pp. 119-127
Author(s):  
Hetong Du ◽  
Yiqing Zhao ◽  
Fuqing Wu ◽  
Peifei Ouyang ◽  
Jinchun Chen ◽  
...  
Keyword(s):  
Threonine Production

scholarly journals L-Threonine Production by a Mutant of Arthrobacter paraffineus

1973 ◽  
Vol 37 (7) ◽  
pp. 1643-1649 ◽  
Author(s):  
Hiroshi KASE ◽  
Kiyoshi NAKAYAMA
Keyword(s):  
Threonine Production

Two-stage carbon distribution and cofactor generation for improvingl-threonine production ofEscherichia coli

2018 ◽  
Vol 116 (1) ◽  
pp. 110-120 ◽  
Author(s):  
Jiaheng Liu ◽  
Huiling Li ◽  
Hui Xiong ◽  
Xixian Xie ◽  
Ning Chen ◽  
...  
Keyword(s):  
Ofescherichia Coli ◽  
Carbon Distribution ◽  
Two Stage ◽  
Threonine Production

scholarly journals Threonine Overproduction in Yeast Strains Carrying theHOM3-R2 Mutant Allele under the Control of Different Inducible Promoters

1999 ◽  
Vol 65 (1) ◽  
pp. 110-116 ◽  
Author(s):  
María-José Farfán ◽  
Luis Aparicio ◽  
Isabel L. Calderón
Keyword(s):  
Mutant Allele ◽  
Metabolic Flux ◽  
Dry Weight ◽  
Yeast Cells ◽  
Aspartate Kinase ◽  
Inducible Promoters ◽  
Yeast Strains ◽  
Threonine Production ◽  
Amino Acid Contents ◽  
Serine Deaminase

ABSTRACT The HOM3 gene of Saccharomyces cerevisiaecodes for aspartate kinase, which plays a crucial role in the regulation of the metabolic flux that leads to threonine biosynthesis. With the aim of obtaining yeast strains able to overproduce threonine in a controlled way, we have placed the HOM3-R2 mutant allele, which causes expression of a feedback-insensitive enzyme, under the control of four distinctive regulatable yeast promoters, namely, P GAL1 , P CHA1 , P CYC1-HSE2 , and P GPH1 . The amino acid contents of strains bearing the different constructs were analyzed both under repression and induction conditions. Although some differences in overall threonine production were found, a maximum of around 400 nmol/mg (dry weight) was observed. Other factors, such as excretion to the medium and activity of the catabolic threonine/serine deaminase, also affect threonine accumulation. Thus, improvement of threonine productivity by yeast cells would probably require manipulation of these and other factors.

scholarly journals Efficient Biofilm-Based Fermentation Strategies for L-Threonine Production by Escherichia coli

2019 ◽  
Vol 10 ◽  
Author(s):  
Tianpeng Chen ◽  
Na Liu ◽  
Peifang Ren ◽  
Xun Xi ◽  
Leyun Yang ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Threonine Production

Factors Improvingl-Threonine Production by a Threel-Threonine Biosynthetic Genes-amplified Recombinant Strain ofBrevibacterium lactofermentum

1994 ◽  
Vol 58 (4) ◽  
pp. 768-770 ◽  
Author(s):  
Masaaki Ishida ◽  
Hiroki Kawashima ◽  
Katsuaki Sato ◽  
Ken-ichi Hashiguchi ◽  
Hisao Ito ◽  
...  
Keyword(s):  
Recombinant Strain ◽  
Biosynthetic Genes ◽  
Threonine Production

Culture Conditions for Improvement ofL-Threonine Production Using a Genetically Self-clonedL-Threonine Hyperproducing Strain ofEscherichia coliK-12

1995 ◽  
Vol 59 (6) ◽  
pp. 1095-1098 ◽  
Author(s):  
Eiko Shimizu ◽  
Tsuyoshi Oosumi ◽  
Haruo Heima ◽  
Takashi Tanaka ◽  
Jun Kurashige ◽  
...  
Keyword(s):  
Culture Conditions ◽  
Threonine Production

scholarly journals Metabolic engineering of a reduced-genome strain of Escherichia coli for L-threonine production

2009 ◽  
Vol 8 (1) ◽  
pp. 2 ◽  
Author(s):  
Jun Lee ◽  
Bong Sung ◽  
Mi Kim ◽  
Frederick R Blattner ◽  
Byoung Yoon ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Metabolic Engineering ◽  
Reduced Genome ◽  
Threonine Production

scholarly journals Optimized medium via statistical approach enhanced threonine production by Pediococcus pentosaceus TL-3 isolated from Malaysian food

2019 ◽  
Vol 18 (1) ◽  
Author(s):  
Ye Heng Lim ◽  
Hooi Ling Foo ◽  
Teck Chwen Loh ◽  
Rosfarizan Mohamad ◽  
Raha Abdul Rahim ◽  
...  
Keyword(s):  
Statistical Approach ◽  
Pediococcus Pentosaceus ◽  
Threonine Production

Improvedl-Threonine Production by the Amplification of the Gene Encoding Homoserine Dehydrogenase inBrevibacterium lactofermentum

1987 ◽  
Vol 51 (1) ◽  
pp. 87-91
Author(s):  
Shigeru Nakamori ◽  
Masaaki Ishida ◽  
Hiroshi Takagi ◽  
Koichi Ito ◽  
Kiyoshi Miwa ◽  
...  
Keyword(s):  
Homoserine Dehydrogenase ◽  
Gene Encoding ◽  
Threonine Production
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