Midtrimester bacterial vaginosis and cervical length in women at risk for preterm birth

2011 ◽  
Vol 2011 ◽  
pp. 140-141
Author(s):  
L.P. Shulman
Keyword(s):  
At Risk ◽  
Preterm Birth ◽  
Bacterial Vaginosis ◽  
Cervical Length

scholarly journals Midtrimester bacterial vaginosis and cervical length in women at risk for preterm birth

2011 ◽  
Vol 204 (4) ◽  
pp. 342.e1-342.e5 ◽  
Author(s):  
Melissa S. Mancuso ◽  
Dana Figueroa ◽  
Jeff M. Szychowski ◽  
Merri Maddox Paden ◽  
John Owen
Keyword(s):  
At Risk ◽  
Preterm Birth ◽  
Bacterial Vaginosis ◽  
Cervical Length

Cervical Length in the Early Second Trimester for Detection of Triplet Pregnancies at Risk for Preterm Birth

2004 ◽  
Vol 23 (9) ◽  
pp. 1187-1191 ◽  
Author(s):  
Sharon Maslovitz ◽  
Joseph Hartoov ◽  
Igal Wolman ◽  
Ariel Jaffa ◽  
Joseph B. Lessing ◽  
...  
Keyword(s):  
At Risk ◽  
Preterm Birth ◽  
Cervical Length ◽  
Second Trimester

scholarly journals Prediction of Spontaneous Preterm Birth in At-risk Women Using Thrombospondin 1 from Cervicovaginal Fluid: A Prospective Observational Study

2021 ◽  
Vol 81 (09) ◽  
pp. 1055-1064
Author(s):  
Johannes Stubert ◽  
Kathleen Gründler ◽  
Bernd Gerber ◽  
Dagmar-Ulrike Richter ◽  
Max Dieterich
Keyword(s):  
At Risk ◽  
Preterm Birth ◽  
Predictive Value ◽  
Transvaginal Ultrasound ◽  
Area Under The Curve ◽  
Cervical Length ◽  
Multiple Gestation ◽  
Spontaneous Preterm Birth ◽  
Thrombospondin 1 ◽  
Cervicovaginal Fluid

Abstract Introduction Thrombospondin 1, desmoplakin and stratifin are putative biomarkers for the prediction of preterm birth. This study aimed to validate the predictive capability of these biomarkers in patients at risk of preterm birth. Materials and Methods We included 109 women with symptoms of threatened spontaneous preterm birth between weeks 20 0/7 and 31 6/7 of gestation. Inclusion criteria were uterine contractions, cervical length of less than 25 mm, or a personal history of spontaneous preterm birth. Multiple gestations were also included. Samples of cervicovaginal fluid were taken before performing a digital examination and transvaginal ultrasound. Levels of cervicovaginal thrombospondin 1, desmoplakin and stratifin were quantified by enzyme-linked immunosorbent assays. The primary endpoint was spontaneous preterm birth before 34 + 0 weeks of gestation. Results Sixteen women (14.7%) delivered before 34 + 0 weeks. Median levels of thrombospondin 1 were higher in samples where birth occurred before 34 weeks vs. ≥ 34 weeks of gestation (4904 vs. 469 pg/mL, p < 0.001). Receiver operator characteristics analysis resulted in an area under the curve of 0.86 (p < 0.0001). At an optimal cut-off value of 2163 pg/mL, sensitivity, specificity, positive predictive value and negative predictive value were 0.94, 0.77, 0.42 and 0.99, respectively, with an adjusted odds ratio of 32.9 (95% CI: 3.1 – 345, p = 0.004). Multiple gestation, cervical length, and preterm labor had no impact on the results. Survival analysis revealed a predictive period of more than eight weeks. Levels of desmoplakin and stratifin did not differ between groups. Conclusion Thrombospondin 1 allowed long-term risk estimation of spontaneous preterm birth.

239: Among women at risk for recurrent preterm birth, is there a cervical length cut-point, above 15mm, that predicts eventual cerclage recommendation?

2017 ◽  
Vol 216 (1) ◽  
pp. S149-S150
Author(s):  
Soha S. Patel ◽  
Amy L. Turitz ◽  
Jamie A. Bastek ◽  
Michal A. Elovitz ◽  
Lisa D. Levine
Keyword(s):  
At Risk ◽  
Preterm Birth ◽  
Cervical Length ◽  
Cut Point

Fetal Fibronectin, Endotoxin, Bacterial Vaginosis and Cervical Length as Predictors of Preterm Birth and Neonatal Morbidity in Twin Pregnancies

1998 ◽  
Vol 53 (7) ◽  
pp. 402-403
Author(s):  
U.-B. Wennerholm ◽  
B. Holm ◽  
I. Mattsby-Baltzer ◽  
T. Nielsen ◽  
J. Platz-Christensen ◽  
...  
Keyword(s):  
Preterm Birth ◽  
Bacterial Vaginosis ◽  
Neonatal Morbidity ◽  
Cervical Length ◽  
Fetal Fibronectin ◽  
Twin Pregnancies

467: Prior full term birth reduces risk of short cervical length in women at risk for preterm birth

2013 ◽  
Vol 208 (1) ◽  
pp. S203
Author(s):  
Amy Turitz ◽  
Jamie Bastek ◽  
Lisa Levine ◽  
Michal Elovitz
Keyword(s):  
At Risk ◽  
Preterm Birth ◽  
Cervical Length ◽  
Full Term ◽  
Term Birth

scholarly journals Genital mycoplasma infection and spontaneous preterm birth outcome: a prospective cohort study

2021 ◽  
Author(s):  
Giulia Cunha ◽  
Larissa Bastos ◽  
Stella Freitas ◽  
Ricardo Cavalli ◽  
Silvana Quintana
Keyword(s):  
Risk Factor ◽  
Preterm Birth ◽  
Bacterial Vaginosis ◽  
Prospective Cohort ◽  
Previous History ◽  
Cervical Length ◽  
Mycoplasma Infection ◽  
Spontaneous Preterm Birth ◽  
History Of ◽  
Tract Infections

Objective To determine the prevalence of genital mycoplasma infection and the risk of spontaneous preterm birth (sPTB) in asymptomatic pregnant women. Design Prospective cohort. Setting Public and private health services in Ribeirão Preto-SP, Brazil. Population 1.349 asymptomatic women with a singleton pregnancy at 20-25 weeks of gestation (WG) recruited between 2010 and 2011. Methods Baseline data was assessed using a questionnaire, in addition to cervicovaginal fluid and blood samples, to analyze lower reproductive tract infections (RTIs) and immune mediators, respectively. The association between variables and the risk of sPTB was evaluated using logistic regression analysis to estimate the odds ratios (ORs). Main outcome measures Genital mycoplasma infection and prematurity. Results The prevalence of the sPTB and genital mycoplasma was 6.8% and 18%, respectively. The infection was not a risk factor for sPTB (aOR 0.66; 95% CI 0.32-1.35), even when associated with bacterial vaginosis (BV). However, it was associated with a low socioeconomic status (p=0.0470), cigarette use (p=0.0009), number of sexual partners (p=0.0019), and BV (p<.0001). Regarding the risk factors associated with sPTB, previous history of PTB (aOR 12.06; 95% CI 6.21-23.43) and a cervical length ≤ 2.5 cm (aOR 3.97; 95% CI 1.67-9.47) were significant. Conclusions The risk of sPTB was independently associated with the history of PTB and the cervical length but not with the genital mycoplasma infection. Funding: This work was founded by CNPq, FAPESP and CAPES. Keywords: Preterm birth, pregnancy, genital mycoplasma, bacterial vaginosis, risk factor

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