Hormonal Responses During Tilt-Table Test in Neurally Mediated Syncope

1997 ◽  
Vol 79 (12) ◽  
pp. 1692-1695 ◽  
Author(s):  
George N. Theodorakis ◽  
Manolis Markianos ◽  
Efthimios G. Livanis ◽  
Elias Zarvalis ◽  
Panagiota Flevari ◽  
...  
2007 ◽  
Vol 31 (2) ◽  
pp. 81-86 ◽  
Author(s):  
Heather A. Nicoletto ◽  
Mark W. Ellis ◽  
Daniel T. Laskowitz ◽  
Ronald J. Kanter ◽  
April E. Perry ◽  
...  

Childhood syncope is common, and there are three categories of causes of syncope: noncardiovascular pseudosyncope, cardiovascular syncope, and neurally mediated syncope. Tilt table testing has become a valuable tool in the evaluation for the cause of syncope in children. Adding transcranial Doppler (TCD) to the tilt table test to monitor the middle cerebral arteries (MCA) adds valuable information about the cerebral blood flow during a syncopal episode and can help the physician differentiate between the various causes of syncope. Three children with frequent syncopal episodes were evaluated using tilt table testing with multimodal monitoring, including TCD. One child, during her syncopal episode, had an increase in blood pressure, heart rate, and MCA flow velocities. This finding was consistent with noncardiovascular pseudosyncope, and she was sent for psychiatric treatment. The other two patients had hypotension, bradycardia, a significant decrease in MCA flow velocities, and an increase in pulsatility indices. Additionally, one of them experienced a 6-sec period of asystole. Both were diagnosed with neurally mediated syncope and were placed on fludrocortisone and a water and salt regimen.


Medicina ◽  
2021 ◽  
Vol 57 (8) ◽  
pp. 808
Author(s):  
Călina-Patricia Țentea ◽  
Csilla-Andrea Eötvös ◽  
Roxana-Daiana Lazar ◽  
Giorgia Paștiu ◽  
Iulia-Georgiana Zehan ◽  
...  

The baseline electrocardiogram (ECG) is less informative in neurally mediated syncope (NMS) than in arrhythmic syncope. However, some of the ECG patterns present in NMS can have diagnostic and prognostic value in such patients. Electrocardiographic documentation of a syncopal spell and thus identification of the ECG changes can be performed during tilt table test (TTT) or during prolonged ECG monitoring. This work reviews the specific ECG patterns in NMS, which are primarily related to the cardioinhibitory reflex. In addition, there are other ECG findings present in patients with NMS that are being analyzed, such as increased heart rate variability as well as specific QRS voltage patterns. In addition to the diagnostic and prognostic value, these ECG patterns in NMS may help improving the selection of patients for pacemaker implant.


2001 ◽  
Vol 24 (10) ◽  
pp. 1494-1499 ◽  
Author(s):  
CHUNYU ZENG ◽  
GUANGYAO LIU ◽  
CHENGMING YANG ◽  
WEI SUN ◽  
YIELI WANG ◽  
...  

2015 ◽  
Vol 67 ◽  
pp. S77
Author(s):  
R.K. Gokhroo ◽  
Kumari Priti ◽  
A. Avinash ◽  
Bhanwar Lal Ranwa ◽  
Kamal Kishor ◽  
...  

Author(s):  
Mohammad Reza Khalilian ◽  
Abdolrahim Ghasemi ◽  
Narges Khazaei ◽  
Sara Khoshkhou ◽  
Elham Mahmoudi

2021 ◽  
Vol 42 (Supplement_1) ◽  
Author(s):  
J M Farinha ◽  
L Parreira ◽  
A F Esteves ◽  
M Fonseca ◽  
A Pinheiro ◽  
...  

Abstract Introduction Reflex syncope is the result of an imbalance between the sympathetic and parasympathetic nervous system. The autonomic nervous system has been associated to some forms of atrial fibrillation (AF). Objective The aim of this study was to assess the prevalence of AF in patients with reflex syncope and a positive tilt table test and to identify the type of tilt test response in patients with AF in comparison to patients without AF. Methods We retrospectively studied consecutive patients that underwent a tilt table test at our institution between 2016 and 2019. We selected those patients with a positive test. Patients with an implanted pacemaker at the time of the tilt test and patients followed in a different institution were excluded. Previous diagnoses of AF episodes were assessed. We analysed the clinical characteristics and the tilt table test results according to previous history of AF. Results We studied 49 patients with a positive tilt test. Seven (14.3%) patients had previously diagnosed paroxysmal AF at the time of the tilt table test. Patients with AF were older, had more frequently hypertension, and the tilt test response was more frequently a vasodepressor than mixed or cardioinhibitory response (71.4% vs. 28.6%) (Table). In univariate analysis, age and hypertension were associated with AF, respectively, OR 1.08 (95% CI 1.01–1.17), p=0.034 and OR 10.80 (95% CI 1.19–98.36), p=0.035. A vasodepressor response was also associated with AF (OR 6.25, 95% CI 1.06–36.74, p=0.043). Conclusions Patients with reflex syncope and a positive tilt table test had a higher prevalence of AF than the general population. A vasodepressor response was associated with AF as were age and hypertension, demonstrating the possible impact of the autonomic nervous system and the multifactorial nature of AF. FUNDunding Acknowledgement Type of funding sources: None.


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