Acquired functional protein s deficiency, cerebral venous thrombosis, and coumarin skin necrosis in association with antiphospholipid syndrome: report of two cases

1989 ◽  
Vol 87 (2) ◽  
pp. 207-210 ◽  
Author(s):  
Jan Moreb ◽  
Craig S. Kitchens
Keyword(s):  
Venous Thrombosis ◽  
Antiphospholipid Syndrome ◽  
Cerebral Venous Thrombosis ◽  
Skin Necrosis ◽  
Protein S ◽  
Protein S Deficiency ◽  
Functional Protein ◽  
S Deficiency ◽  
Syndrome Report

Cerebral venous thrombosis in young adult with familial protein S deficiency

2015 ◽  
Vol 26 (3) ◽  
pp. 342-345 ◽  
Author(s):  
Franciele M. Amaral ◽  
Caroline Ribeiro da Silva ◽  
Michelle G. Borém ◽  
Ana L. Miranda-Vilela
Keyword(s):  
Young Adult ◽  
Venous Thrombosis ◽  
Cerebral Venous Thrombosis ◽  
Protein S ◽  
Protein S Deficiency ◽  
S Deficiency

Cerebral venous thrombosis due to protein S deficiency in pregnancy

The Lancet ◽  
2002 ◽  
Vol 359 (9309) ◽  
pp. 892 ◽  
Author(s):  
Jorge G Burneo ◽  
Stanton B Elias ◽  
Gregory L Barkley
Keyword(s):  
Venous Thrombosis ◽  
Cerebral Venous Thrombosis ◽  
Protein S ◽  
Protein S Deficiency ◽  
S Deficiency ◽  
In Pregnancy

scholarly journals POSTPARTUM CEREBRAL VENOUS THROMBOSIS ASSOCIATED WITH PROTEIN S DEFICIENCY: A CASE REPORT

2020 ◽  
Vol 06 (03) ◽  
pp. 114-116
Author(s):  
Shakshi Singh ◽  
Elvia Jamatia ◽  
Binita Goswami ◽  
Anuradha Subramanian
Keyword(s):  
Case Report ◽  
Venous Thrombosis ◽  
Cerebral Venous Thrombosis ◽  
Protein S ◽  
Protein S Deficiency ◽  
S Deficiency

scholarly journals A case of cerebral venous thrombosis due to protein S deficiency

Nosotchu ◽  
2019 ◽  
Vol 41 (5) ◽  
pp. 390-393
Author(s):  
Shun Suzuki ◽  
Masanori Yoshino ◽  
Takayuki Hara
Keyword(s):  
Venous Thrombosis ◽  
Cerebral Venous Thrombosis ◽  
Protein S ◽  
Protein S Deficiency ◽  
S Deficiency

Severe Acquired Functional Protein S Deficiency and Skin Necrosis in a Patient with ANCA-associated Vasculitis

2000 ◽  
Vol 84 (11) ◽  
pp. 929-930 ◽  
Author(s):  
David Joyce ◽  
Warren Piette ◽  
Mary Stone ◽  
Thomas Carlisle ◽  
Steven Lentz
Keyword(s):  
Skin Necrosis ◽  
Protein S ◽  
Protein S Deficiency ◽  
Functional Protein ◽  
Anca Associated Vasculitis ◽  
S Deficiency

The Frequency of Type I Heterozygous Protein S and Protein C Deficiency in 141 Unrelated Young Patients with Venous Thrombosis

1988 ◽  
Vol 59 (01) ◽  
pp. 018-022 ◽  
Author(s):  
C L Gladson ◽  
I Scharrer ◽  
V Hach ◽  
K H Beck ◽  
J H Griffin
Keyword(s):  
Venous Thrombosis ◽  
Protein C ◽  
Antithrombin Iii ◽  
Young Patients ◽  
Protein S ◽  
Type I ◽  
Protein S Deficiency ◽  
Protein C Deficiency ◽  
Low Protein ◽  
S Deficiency

SummaryThe frequency of heterozygous protein C and protein S deficiency, detected by measuring total plasma antigen, in a group (n = 141) of young unrelated patients (<45 years old) with venous thrombotic disease was studied and compared to that of antithrombin III, fibrinogen, and plasminogen deficiencies. Among 91 patients not receiving oral anticoagulants, six had low protein S antigen levels and one had a low protein C antigen level. Among 50 patients receiving oral anticoagulant therapy, abnormally low ratios of protein S or C to other vitamin K-dependent factors were presented by one patient for protein S and five for protein C. Thus, heterozygous Type I protein S deficiency appeared in seven of 141 patients (5%) and heterozygous Type I protein C deficiency in six of 141 patients (4%). Eleven of thirteen deficient patients had recurrent venous thrombosis. In this group of 141 patients, 1% had an identifiable fibrinogen abnormality, 2% a plasminogen abnormality, and 3% an antithrombin III deficiency. Thus, among the known plasma protein deficiencies associated with venous thrombosis, protein S and protein C. deficiencies (9%) emerge as the leading identifiable associated abnormalities.

Sign in / Sign up

Export Citation Format

Share Document