Effects of diet consistency on the myosin heavy chain mRNAs of rat masseter muscle during postnatal development

2002 ◽  
Vol 47 (2) ◽  
pp. 109-115 ◽  
Author(s):  
T. Saito ◽  
Y. Ohnuki ◽  
A. Yamane ◽  
Y. Saeki
Keyword(s):  
Myosin Heavy Chain ◽  
Postnatal Development ◽  
Heavy Chain ◽  
Masseter Muscle ◽  
Diet Consistency

scholarly journals Regulation of an antisense RNA with the transition of neonatal to IIb myosin heavy chain during postnatal development and hypothyroidism in rat skeletal muscle

2012 ◽  
Vol 302 (7) ◽  
pp. R854-R867 ◽  
Author(s):  
Clay E. Pandorf ◽  
Weihua Jiang ◽  
Anqi X. Qin ◽  
Paul W. Bodell ◽  
Kenneth M. Baldwin ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Myosin Heavy Chain ◽  
Postnatal Development ◽  
Heavy Chain ◽  
Antisense Rna ◽  
Transcriptional Repression ◽  
Mhc Genes ◽  
Regulatory Model ◽  
A Site ◽  
Comparative Phylogenetic Analysis

Postnatal development of fast skeletal muscle is characterized by a transition in expression of myosin heavy chain (MHC) isoforms, from primarily neonatal MHC at birth to primarily IIb MHC in adults, in a tightly coordinated manner. These isoforms are encoded by distinct genes, which are separated by ∼17 kb on rat chromosome 10. The neonatal-to-IIb MHC transition is inhibited by a hypothyroid state. We examined RNA products [mRNA, pre-mRNA, and natural antisense transcript (NAT)] of developmental and adult-expressed MHC genes (embryonic, neonatal, I, IIa, IIx, and IIb) at 2, 10, 20, and 40 days after birth in normal and thyroid-deficient rat neonates treated with propylthiouracil. We found that a long noncoding antisense-oriented RNA transcript, termed bII NAT, is transcribed from a site within the IIb-Neo intergenic region and across most of the IIb MHC gene. NATs have previously been shown to mediate transcriptional repression of sense-oriented counterparts. The bII NAT is transcriptionally regulated during postnatal development and in response to hypothyroidism. Evidence for a regulatory mechanism is suggested by an inverse relationship between IIb MHC and bII NAT in normal and hypothyroid-treated muscle. Neonatal MHC transcription is coordinately expressed with bII NAT. A comparative phylogenetic analysis also suggests that bII NAT-mediated regulation has been a conserved trait of placental mammals for most of the eutherian evolutionary history. The evidence in support of the regulatory model implicates long noncoding antisense RNA as a mechanism to coordinate the transition between neonatal and IIb MHC during postnatal development.

scholarly journals Maximum Shortening Velocity and Myosin Heavy-chain Isoform Expression in Human Masseter Muscle Fibers

2001 ◽  
Vol 80 (9) ◽  
pp. 1845-1848 ◽  
Author(s):  
T.J. Morris ◽  
C.A. Branden ◽  
M.J. Horton ◽  
D.S. Carlson ◽  
J.J. Sciote
Keyword(s):  
Myosin Heavy Chain ◽  
Heavy Chain ◽  
Masseter Muscle ◽  
Muscle Fibers ◽  
Shortening Velocity ◽  
Myosin Heavy Chain Isoform ◽  
Isoform Expression

scholarly journals Effects of Chronic Akt/mTOR Inhibition by Rapamycin on Mechanical Overload–Induced Hypertrophy and Myosin Heavy Chain Transition in Masseter Muscle

2013 ◽  
Vol 122 (4) ◽  
pp. 278-288 ◽  
Author(s):  
Daisuke Umeki ◽  
Yoshiki Ohnuki ◽  
Yasumasa Mototani ◽  
Kouichi Shiozawa ◽  
Takayuki Fujita ◽  
...  
Keyword(s):  
Myosin Heavy Chain ◽  
Heavy Chain ◽  
Masseter Muscle ◽  
Mtor Inhibition ◽  
Mechanical Overload

scholarly journals Fetal myosin heavy chain increases in the human masseter muscle during aging

FEBS Letters ◽  
1996 ◽  
Vol 386 (1) ◽  
pp. 87-90 ◽  
Author(s):  
Mehrdad Monemi ◽  
Per-Olof Eriksson ◽  
Ihari Dubail ◽  
Gillian S. Butler-Browne ◽  
Lars-Erik Thornell
Keyword(s):  
Myosin Heavy Chain ◽  
Heavy Chain ◽  
Masseter Muscle

scholarly journals Role of cyclic AMP sensor Epac1 in masseter muscle hypertrophy and myosin heavy chain transition induced by β 2 ‐adrenoceptor stimulation

2014 ◽  
Vol 592 (24) ◽  
pp. 5461-5475 ◽  
Author(s):  
Yoshiki Ohnuki ◽  
Daisuke Umeki ◽  
Yasumasa Mototani ◽  
Huiling Jin ◽  
Wenqian Cai ◽  
...  
Keyword(s):  
Cyclic Amp ◽  
Myosin Heavy Chain ◽  
Heavy Chain ◽  
Masseter Muscle ◽  
Muscle Hypertrophy

Single-fiber myosin heavy chain polymorphism during postnatal development: modulation by hypothyroidism

2000 ◽  
Vol 278 (4) ◽  
pp. R1099-R1106 ◽  
Author(s):  
Nick A. di Maso ◽  
Vincent J. Caiozzo ◽  
Kenneth M. Baldwin
Keyword(s):  
Myosin Heavy Chain ◽  
Postnatal Development ◽  
Heavy Chain ◽  
Time Course ◽  
Developmental Time ◽  
General Concept ◽  
Primary Objective ◽  
Single Fiber ◽  
Fiber Types ◽  
Mhc Polymorphism

The primary objective of this study was to follow the developmental time course of myosin heavy chain (MHC) isoform transitions in single fibers of the rodent plantaris muscle. Hypothyroidism was used in conjunction with single-fiber analyses to better describe a possible linkage between the neonatal and fast type IIB MHC isoforms during development. In contrast to the general concept that developmental MHC isoform transitions give rise to muscle fibers that express only a single MHC isoform, the single-fiber analyses revealed a very high degree of MHC polymorphism throughout postnatal development. In the adult state, MHC polymorphism was so pervasive that the rodent plantaris muscles contained ∼12–15 different pools of fibers (i.e., fiber types). The degree of polymorphism observed at the single-fiber level made it difficult to determine specific developmental schemes analogous to those observed previously for the rodent soleus muscle. However, hypothyroidism was useful in that it confirmed a possible link between the developmental regulation of the neonatal and fast type IIB MHC isoforms.

Sexual Dimorphism in the Rabbit Masseter Muscle: Myosin Heavy Chain Composition of Neuromuscular Compartments

1999 ◽  
Vol 164 (4) ◽  
pp. 179-191 ◽  
Author(s):  
Arthur W. English ◽  
Jane Eason ◽  
Gail Schwartz ◽  
Anne Shirley ◽  
Dario I. Carrasco
Keyword(s):  
Sexual Dimorphism ◽  
Myosin Heavy Chain ◽  
Heavy Chain ◽  
Masseter Muscle ◽  
Chain Composition ◽  
Myosin Heavy Chain Composition ◽  
Neuromuscular Compartments ◽  
Muscle Myosin

scholarly journals Abundant expression of myosin heavy-chain IIB RNA in a subset of human masseter muscle fibres

2001 ◽  
Vol 46 (11) ◽  
pp. 1039-1050 ◽  
Author(s):  
Michael J Horton ◽  
Carla A Brandon ◽  
Terence J Morris ◽  
Thomas W Braun ◽  
Kenneth M Yaw ◽  
...  
Keyword(s):  
Myosin Heavy Chain ◽  
Heavy Chain ◽  
Masseter Muscle ◽  
Muscle Fibres
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