Diabetes predicts decreased quality of life among community-dwelling seniors undertaking progressive resistance exercise: an observational study

Objective:This paper reviews the therapeutically beneficial effects of progressive resistance exercise training (PRET) on motor and nonmotor symptoms in Parkinson's disease (PD).Methods:First, we perform a systematic review of the literature on the effects of PRET on motor signs of PD, functional outcomes, quality of life, and patient perceived improvement, strength, and cognition in PD. Second, we perform a meta-analysis on the motor section of the UPDRS. Finally, we discuss the results of our review and we identify current knowledge gaps regarding PRET in PD.Conclusion:This systematic review synthesizes evidence that PRET can improve strength and motor signs of Parkinsonism in PD and may also be beneficial for physical function in individuals with PD. Further research is needed to explore the effects of PRET on nonmotor symptoms such as depression, cognitive impairment, autonomic nervous system dysfunction, and quality of life in individuals with PD.

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Comparison of Neuromotor and Progressive Resistance Exercise Training to Improve Mobility and Fitness in Community-Dwelling Older Women

Journal of Science in Sport and Exercise ◽

10.1007/s42978-019-0017-4 ◽

2019 ◽

Vol 1 (2) ◽

pp. 124-131

Author(s):

Roberta Forte ◽

G. De Vito

Keyword(s):

Exercise Training ◽

Resistance Exercise ◽

Older Women ◽

Community Dwelling ◽

Resistance Exercise Training ◽

Progressive Resistance Exercise ◽

Progressive Resistance

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Effects of modest testosterone supplementation and exercise for 12 weeks on body composition and quality of life in elderly men

Acta Endocrinologica ◽

10.1530/eje.1.02291 ◽

2006 ◽

Vol 155 (6) ◽

pp. 867-875 ◽

Cited By ~ 37

Author(s):

Laurence Katznelson ◽

Mara W Robinson ◽

Caryn L Coyle ◽

Hang Lee ◽

Christina E Farrell

Keyword(s):

Quality Of Life ◽

Body Composition ◽

Resistance Exercise ◽

Exercise Program ◽

Serum Testosterone ◽

Exercise Group ◽

Community Dwelling ◽

Elderly Men ◽

Home Based

Objective: One of the factors that may promote deterioration in quality of life and body composition in elderly men is the relative decline in serum testosterone levels with aging. In this study, we assessed the effects of modest doses of testosterone and a home-based strengthening program on quality of life and body composition in elderly men with relative testosterone insufficiency. Design: Double-blind, placebo-controlled randomized study (testosterone), and additional randomization to a resistance exercise program or no additional exercise for 12 weeks in men between ages of 65 and 85 years with relative testosterone insufficiency. Methods: Seventy sedentary, community dwelling men were randomized to a 5 mg testoderm transdermal system applied daily vs placebo system, and additionally randomized to a home-based resistance exercise program. Subjects were randomized to Group 1 (testosterone plus exercise), Group 2 (testosterone plus no exercise), Group 3 (placebo plus exercise), and Group 4 (placebo plus no exercise). Endpoints included quality of life (assessed by the short form-36 questionnaire) and body composition (measured by dual x-ray absorptiometry scan). Results: Serum testosterone increased by a mean of 10.0 ± 1.9, 6.6 ± 1.6, 0.52 ± 0.6, and 0.5 ± 0.6 nmol/l in Groups 1, 2, 3, and 4 respectively. There was a significant interaction of testosterone and exercise on quality of life in the domains of physical functioning (P = 0.03), role physical (P = 0.01), general health (P = 0.049), and social functioning (P = 0.04). There were no effects of testosterone or exercise on quality of life alone, nor in body composition parameters. Conclusions: Modest testosterone supplementation to elderly men with relative testosterone insufficiency improved quality of life when accompanied by an exercise program. The combination of testosterone and exercise may be an important strategy in the elderly, though further studies are necessary to determine the long-term impact on body composition and function and for analysis of risk/benefit ratios as well.

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Pain and health-related quality of life (HRQoL): a national observational study in community-dwelling older adults

European Geriatric Medicine ◽

10.1007/s41999-018-0114-7 ◽

2018 ◽

Vol 9 (6) ◽

pp. 881-889 ◽

Cited By ~ 2

Author(s):

Christine Cedraschi ◽

C. Ludwig ◽

A. F. Allaz ◽

F. R. Herrmann ◽

C. Luthy

Keyword(s):

Quality Of Life ◽

Older Adults ◽

Observational Study ◽

Community Dwelling ◽

Health Related Quality ◽

Related Quality ◽

Health Related ◽

Community Dwelling Older Adults

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Costs and quality of life in community-dwelling patients with Alzheimer's disease in Spain: results from the GERAS II observational study

International Psychogeriatrics ◽

10.1017/s1041610217001211 ◽

2017 ◽

Vol 29 (12) ◽

pp. 2081-2093 ◽

Cited By ~ 10

Author(s):

Javier Olazarán ◽

Luis Agüera-Ortiz ◽

Josep María Argimón ◽

Catherine Reed ◽

Antonio Ciudad ◽

...

Keyword(s):

Quality Of Life ◽

Observational Study ◽

Informal Care ◽

Resource Use ◽

Community Dwelling ◽

P Value ◽

Societal Costs ◽

Informal Care Costs ◽

Care Costs

ABSTRACTBackground:Country-specific data on resource use and costs associated with Alzheimer's disease (AD) help inform governments about the increasing need for medical and financial support as the disease increases in prevalence.Methods:GERAS II, a prospective observational study, assessed resource use, costs, and health-related quality of life (HRQoL) among patients with AD and their caregivers in Spain. Community-dwelling patients aged ≥55 years with probable AD, and their primary caregivers, were recruited by study investigators during routine clinical practice and assessed as having mild, moderate, or moderately severe/severe (MS/S) AD dementia based on patient Mini-Mental State Examination scores. Costs of AD were calculated by applying costs to resource-use data obtained in caregiver interviews using the Resource Utilization in Dementia instrument. Total societal costs included patients’ health and social care costs and caregiver informal care costs. Baseline results are presented.Results:Total mean monthly societal costs/patient (2013 values) were €1514 for mild (n = 116), €2082 for moderate (n = 118), and €2818 for MS/S AD dementia (n = 146) (p value <0.001 between groups). Caregiver informal care costs comprised most of the total societal costs and differed significantly between groups (€1050, €1239, €1580, respectively; p value = 0.013), whereas patient healthcare costs did not. Across AD dementia severity groups, patient HRQoL (measured by proxy) decreased significantly (p value <0.001), caregiver subjective burden significantly increased (p value <0.001) and caregiver HRQoL was similar.Conclusions:Societal costs associated with AD in Spain were largely attributable to caregiver informal care costs and increased with increasing AD dementia severity.

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