Modifying the substrate specificity of penicillin G acylase to cephalosporin acylase by mutating active-site residues

2004 ◽  
Author(s):  
B OH
Keyword(s):  
Substrate Specificity ◽  
Active Site ◽  
Penicillin G Acylase ◽  
Penicillin G ◽  
Active Site Residues ◽  
Cephalosporin Acylase

scholarly journals Redesigning the Substrate Specificity of an Enzyme by Cumulative Effects of the Mutations of Non-active Site Residues

1999 ◽  
Vol 274 (4) ◽  
pp. 2344-2349 ◽  
Author(s):  
Shinya Oue ◽  
Akihiro Okamoto ◽  
Takato Yano ◽  
Hiroyuki Kagamiyama
Keyword(s):  
Substrate Specificity ◽  
Active Site ◽  
Cumulative Effects ◽  
Active Site Residues

scholarly journals Mechanism of the Flavoprotein d-6-Hydroxynicotine Oxidase: Substrate Specificity, pH and Solvent Isotope Effects, and Roles of Key Active-Site Residues

Biochemistry ◽  
2019 ◽  
Vol 58 (21) ◽  
pp. 2534-2541
Author(s):  
Paul F. Fitzpatrick ◽  
Vi Dougherty ◽  
Bishnu Subedi ◽  
Jesus Quilantan ◽  
Cynthia S. Hinck ◽  
...  
Keyword(s):  
Substrate Specificity ◽  
Active Site ◽  
Isotope Effects ◽  
Active Site Residues ◽  
Solvent Isotope ◽  
Solvent Isotope Effects

Substrate Specificity Engineering of β-Mannosidase and β-Glucosidase fromPyrococcusby Exchange of Unique Active Site Residues†

Biochemistry ◽  
2002 ◽  
Vol 41 (12) ◽  
pp. 4147-4155 ◽  
Author(s):  
Thijs Kaper ◽  
Hester H. van Heusden ◽  
Bert van Loo ◽  
Andrea Vasella ◽  
John van der Oost ◽  
...  
Keyword(s):  
Substrate Specificity ◽  
Active Site ◽  
Active Site Residues

Isolation and mapping of a mutant penicillin G acylase with altered substrate specificity from Escherichia coli

1995 ◽  
Vol 17 (1) ◽  
pp. 19-23 ◽  
Author(s):  
Helmut Niersbach ◽  
Walter Tischer ◽  
Marijke Weber ◽  
Frank Wedekind ◽  
Roland Plapp
Keyword(s):  
Escherichia Coli ◽  
Substrate Specificity ◽  
Penicillin G Acylase ◽  
Penicillin G

Role of active-site residues Tyr55 and Tyr114 in catalysis and substrate specificity ofCorynebacterium diphtheriaeC-S lyase

2014 ◽  
Vol 83 (1) ◽  
pp. 78-90 ◽  
Author(s):  
Alessandra Astegno ◽  
Alessandra Allegrini ◽  
Stefano Piccoli ◽  
Alejandro Giorgetti ◽  
Paola Dominici
Keyword(s):  
Substrate Specificity ◽  
Active Site ◽  
Active Site Residues

scholarly journals New active site oriented glyoxyl-agarose derivatives of Escherichia coli penicillin G acylase

2007 ◽  
Vol 7 (1) ◽  
pp. 54 ◽  
Author(s):  
Davide A Cecchini ◽  
Immacolata Serra ◽  
Daniela Ubiali ◽  
Marco Terreni ◽  
Alessandra M Albertini
Keyword(s):  
Escherichia Coli ◽  
Active Site ◽  
Penicillin G Acylase ◽  
Penicillin G ◽  
Derivatives Of

Active site residues controlling substrate specificity in 2-nitrotoluene dioxygenase from Acidovorax sp. strain JS42

2005 ◽  
Vol 32 (10) ◽  
pp. 465-473 ◽  
Author(s):  
Kyung-Seon Lee ◽  
Juanito V. Parales ◽  
Rosmarie Friemann ◽  
Rebecca E. Parales
Keyword(s):  
Substrate Specificity ◽  
Active Site ◽  
Active Site Residues
Sign in / Sign up

Export Citation Format

Share Document