Myoglobin, creatine kinase MB isoforms and creatine kinase MB mass in early diagnosis of myocardial infarction in patients with acute chest pain

2002 ◽  
Vol 35 (8) ◽  
pp. 647-653 ◽  
Author(s):  
Karri Penttilä ◽  
Heli Koukkunen ◽  
Matti Halinen ◽  
Tapio Rantanen ◽  
Kalevi Pyörälä ◽  
...  
Heart ◽  
1981 ◽  
Vol 45 (4) ◽  
pp. 389-392 ◽  
Author(s):  
A P Freeman ◽  
K R Fatches ◽  
I W Carter ◽  
M J Cloonan ◽  
D E Wilcken

1999 ◽  
Vol 29 (2) ◽  
pp. 93-101 ◽  
Author(s):  
K. Penttilä ◽  
H. Koukkunen ◽  
A. Kemppainen ◽  
M. Halinen ◽  
T. Rantanen ◽  
...  

1999 ◽  
Vol 83 (8) ◽  
pp. 1175-1179 ◽  
Author(s):  
Carı́si A Polanczyk ◽  
Paula A Johnson ◽  
E.Francis Cook ◽  
Thomas H Lee

1977 ◽  
Vol 23 (2) ◽  
pp. 245-249 ◽  
Author(s):  
J Griffiths ◽  
S Shaw

Abstract Enzyme "panels," in which creatine kinase and lactate dehydrogenase activities in serum are measured, are useful indicators of myocardial infarction. We examined a further enzyme, glyceraldehyde-phosphate dehydrogenase (EC 1.2.1.12), by comparison with creatine kinase (EC 2.7.3.2), in the early diagnosis of such infarctions. Results indicate that this total dehydrogenase appears in the serum before total creatine kinase activity; however, the lack of cardio-specificity relating to the dehydrogenase isoenzyme fraction 2 in comparison to the creatine kinase MB band is a major disadvantage, as is its relatively poor in vitro stability. We conclude that measurement of this dehydrogenase does not allow a substantially earlier diagnosis of myocardial infarction.


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