Modeling uncertainty in clinical trial simulations: A bayesian approach

Clinical Pharmacology & Therapeutics ◽

10.1016/s0009-9236(99)80258-6 ◽

1999 ◽

Vol 65 (2) ◽

pp. 182-182

Author(s):

W GILLESPIE ◽

M SALE ◽

M GASTONGUAY

Keyword(s):

Clinical Trial ◽

Bayesian Approach ◽

Modeling Uncertainty ◽

Clinical Trial Simulations

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A Statistical Approach to Clinical Trial Simulations

Biopharmaceutical Applied Statistics Symposium - ICSA Book Series in Statistics ◽

10.1007/978-981-10-7829-3_1 ◽

2018 ◽

pp. 1-18

Author(s):

Stephan Ogenstad

Keyword(s):

Clinical Trial ◽

Statistical Approach ◽

Clinical Trial Simulations

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Clinical Trial Simulations for Earlier Development Phases

Encyclopedia of Biopharmaceutical Statistics, Third Edition ◽

10.1201/b14674-47 ◽

2012 ◽

pp. 285-289

Author(s):

Mark Chang

Keyword(s):

Clinical Trial ◽

Clinical Trial Simulations ◽

Development Phases

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Bayesian Approach for Clinical Trial Safety Data Using an Ising Prior

10.1111/biom.12051 ◽

2013 ◽

Vol 69 (3) ◽

pp. 661-672 ◽

Author(s):

Bradley W. McEvoy ◽

Rajesh R. Nandy ◽

Ram C. Tiwari

Keyword(s):

Clinical Trial ◽

Bayesian Approach ◽

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Clinical Trial Simulations

10.1007/978-1-4419-7415-0 ◽

2011 ◽

Keyword(s):

Clinical Trial ◽

Clinical Trial Simulations

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A semiparametric Bayesian approach to population finding with time‐to‐event and toxicity data in a randomized clinical trial

10.1111/biom.13289 ◽

2020 ◽

Author(s):

Satoshi Morita ◽

Peter Müller ◽

Hiroyasu Abe

Keyword(s):

Clinical Trial ◽

Randomized Clinical Trial ◽

Bayesian Approach ◽

Toxicity Data ◽

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Stopping a clinical trial early because of toxicity: The Bayesian approach

Controlled Clinical Trials ◽

10.1016/0197-2456(95)00046-j ◽

1995 ◽

Vol 16 (2) ◽

pp. 131-132

Author(s):

Johan Bring

Keyword(s):

Clinical Trial ◽

Bayesian Approach ◽

The Bayesian Approach

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Improving Realism in Clinical Trial Simulations via Real-World Data

CPT Pharmacometrics & Systems Pharmacology ◽

10.1002/psp4.12232 ◽

2017 ◽

Vol 6 (11) ◽

pp. 727-729 ◽

Author(s):

Holly Kimko ◽

Kwan Lee

Keyword(s):

Clinical Trial ◽

Real World Data ◽

Clinical Trial Simulations

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Clinical Trial Simulations Based on A Meta-Analysis of Studies In Patients With Locally Advanced and/or Metastatic Adenocarcinoma Pancreatic Cancer Receiving Gemcitabine (GEM) Alone or In Combination

Value in Health ◽

10.1016/j.jval.2017.08.107 ◽

2017 ◽

Vol 20 (9) ◽

pp. A416

Author(s):

M Bennetts ◽

DJ Nickens ◽

HC Thurm ◽

CJ Hernandez ◽

S Ahadieh ◽

...

Keyword(s):

Pancreatic Cancer ◽

Clinical Trial ◽

Meta Analysis ◽

Locally Advanced ◽

Metastatic Adenocarcinoma ◽

Clinical Trial Simulations

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Incorporating In Vitro Information on Drug Metabolism Into Clinical Trial Simulations to Assess the Effect of CYP2D6 Polymorphism on Pharmacokinetics and Pharmacodynamics: Dextromethorphan as a Model Application

The Journal of Clinical Pharmacology ◽

10.1177/0091270006294279 ◽

2007 ◽

Vol 47 (2) ◽

pp. 175-186 ◽

Author(s):

Gemma L. Dickinson ◽

Saeed Rezaee ◽

Nicholas J. Proctor ◽

Martin S. Lennard ◽

Geoffrey T. Tucker ◽

...

Keyword(s):

Clinical Trial ◽

Drug Metabolism ◽

Pharmacokinetics And Pharmacodynamics ◽

Model Application ◽

Cyp2d6 Polymorphism ◽

Clinical Trial Simulations

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Clinical trial simulations of the interaction between cannabidiol and clobazam and effect on drop‐seizure frequency

British Journal of Clinical Pharmacology ◽

10.1111/bcp.14158 ◽

2019 ◽

Vol 86 (2) ◽

pp. 380-385 ◽

Author(s):

Kirsten Riber Bergmann ◽

Karen Broekhuizen ◽

Geert Jan Groeneveld

Keyword(s):

Clinical Trial ◽

Seizure Frequency ◽

Clinical Trial Simulations

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