Efficacy of methotrexate treatment in extrauterine pregnancies defined by stable or increasing human chorionic gonadotropin concentrations1 1Lis Maternity Hospital is affiliated with the Sackler Faculty of Medicine, Tel Aviv University, Israel.

2002 ◽  
Vol 77 (4) ◽  
pp. 761-765 ◽  
Author(s):  
Ronni Gamzu ◽  
Benny Almog ◽  
Yishai Levin ◽  
Amiram Avni ◽  
Ariel Jaffa ◽  
...  
Keyword(s):  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Maternity Hospital ◽  
Tel Aviv ◽  
Sackler Faculty ◽  
Methotrexate Treatment

scholarly journals Human chorionic gonadotropin value and its change prior to methotrexate treatment can predict the prognosis in ectopic tubal pregnancies

2018 ◽  
Vol 18 (1) ◽  
pp. 51-56
Author(s):  
Koichi Watanabe ◽  
Yoshitsugu Chigusa ◽  
Eiji Kondoh ◽  
Haruta Mogami ◽  
Akihito Horie ◽  
...  
Keyword(s):  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Methotrexate Treatment

scholarly journals Beta-Human Chorionic Gonadotropin and Uterine Artery Doppler Measurements for the Prediction of Success of Single Dose Methotrexate Treatment in Tubal Ectopic Pregnancies

2016 ◽  
Vol 22 (1) ◽  
Author(s):  
Kılıç Çiğdem ◽  
Mehmet Metin Altay ◽  
Tuğba Kınay ◽  
Metin Kaplan ◽  
Serap Fırtına Tuncer ◽  
...  
Keyword(s):  
Single Dose ◽  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Multiple Dose ◽  
Uterine Artery ◽  
Methotrexate Therapy ◽  
Uterine Artery Doppler ◽  
Dose Methotrexate ◽  
Methotrexate Treatment ◽  
Β Hcg

<p>Objectives: To evaluate the impact of the uterine artery Doppler values and the change of β-Human chorionic gonadotropin (β-HCG) levels from day 0 to day 4 for prediction of the success of single dose methotrexate treatment in tubal pregnancy cases. <br />Study Design: 50 patients with tubal pregnancy were included the prospective study. The location and size of ectopic pregnancy, bilateral uterine artery pulsed color doppler imaging was examined by ultrasonography and serum β-HCG levels were measured on day 0, 4, 7 of treatment. Success was defined as decrease of β-HCG level &lt;10 mIU/mL with single dose methotrexate treatment. Multiple dose methotrexate treatment and surgical treatment were considered as treatment failure.<br />Results: 32 patients (64%) treated with single dose methotrexate, 14 patients (28%) treated with multiple dose methotrexate, and 4 patients (8%) treated with surgery. In the group with β-HCG level decrease &gt; 15.04% on day 4, single-dose methotrexate therapy were 3.82 times more successful than the group without &gt; 15.04% β-HCG decrease. However, no significant alteration of uterine artery Doppler measurements was determined on the same days.<br />Conclusion: Reduction rate in the β-HCG level on day 4 of treatment can be used in determination the success of single-dose methotrexate therapy. <br /><br /></p>

Risk factors and human chorionic gonadotropin trends in patients with ruptured tubal ectopic pregnancies despite methotrexate treatment

2018 ◽  
Vol 35 (1) ◽  
pp. 49-52 ◽  
Author(s):  
Anne P. Hutchinson ◽  
Nigel Pereira ◽  
Eric R. Chung ◽  
Nirali J. Shah ◽  
Megi Zeku ◽  
...  
Keyword(s):  
Risk Factors ◽  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Methotrexate Treatment ◽  
Ectopic Pregnancies
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