Recruitment of Follicles by Recombinant Human Follicle-Stimulating Hormone Commencing in the Luteal Phase of the Ovarian Cycle

The present study reports the pulsatile secretion of gonadotrophins and 17β-oestradiol (OE2) on the day of oestrus and at the mid-luteal phase of the oestrous cycle in mithun (Bos frontalis). The frequency of luteinising hormone (LH) and follicle-stimulating hormone (FSH) pulses was found to be greater (P < 0.05) on the day of oestrus than at the mid-luteal phase. In contrast, the amplitude of the LH and FSH pulses was greater (P < 0.01) at the mid-luteal phase than on the day of oestrus. A synchronised (P < 0.01) LH and FSH secretion pattern was found only at the mid-luteal phase. A pulsatile secretion pattern for OE2 in the peripheral circulation was evident for both phases of the oestrous cycle. The frequency of the OE2 pulses did not differ significantly in different phases of the oestrous cycle. In contrast, the amplitude of the OE2 pulses and the basal OE2 concentration were found to be greater (P < 0.01) at the mid-luteal phase than on the day of oestrus. A synchronised (P < 0.01) LH and OE2 secretion pattern was observed in both phases of the oestrous cycle. In contrast, a synchronised (P < 0.05) FSH and OE2 secretion pattern was found only on the day of oestrus. In conclusion, a different pattern of LH and FSH secretion was observed in both phases of the oestrous cycle, mainly on the day of oestrus, which indicates a differential regulatory mechanism of LH and FSH release. In addition, as in cattle, OE2 exerts a positive feedback on LH and FSH release on the day of oestrus and on LH release at the mid-luteal phase of the oestrous cycle in mithun. Also, as in cattle, the greater basal plasma OE2 concentration and increased amplitude of OE2 pulses exert a negative feedback on FSH release at the mid-luteal phase of the oestrous cycle.

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Homologous in vitro bioassay for follicle-stimulating hormone (FSH) reveals increased FSH biological signal during the mid- to late luteal phase of the human menstrual cycle

The Journal of Clinical Endocrinology & Metabolism ◽

10.1210/jc.81.6.2080 ◽

1996 ◽

Vol 81 (6) ◽

pp. 2080-2088 ◽

Cited By ~ 9

Author(s):

S. Christin-Maitre

Keyword(s):

Menstrual Cycle ◽

Luteal Phase ◽

Follicle Stimulating Hormone ◽

In Vitro Bioassay ◽

Biological Signal ◽

Late Luteal Phase ◽

Human Menstrual Cycle ◽

Stimulating Hormone

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Normal Menstrual Cycle

10.2310/obg.19094 ◽

2018 ◽

Author(s):

Rebecca Pierson ◽

Kelly Pagidas

Keyword(s):

Menstrual Cycle ◽

Luteinizing Hormone ◽

Luteal Phase ◽

Follicle Stimulating Hormone ◽

Follicular Phase ◽

Gonadotropin Releasing Hormone ◽

Hormonal Control ◽

Releasing Hormone ◽

Normal Menstrual Cycle ◽

Stimulating Hormone

A normal menstrual cycle is the end result of a sequence of purposeful and coordinated events that occur from intact hypothalamic-pituitary-ovarian and uterine axes. The menstrual cycle is under hormonal control in the reproductively active female and is functionally divided into two phases: the proliferative or follicular phase and the secretory or luteal phase. This tight hormonal control is orchestrated by a series of negative and positive endocrine feedback loops that alter the frequency of the pulsatile secretion of gonadotropin-releasing hormone (GnRH), the pituitary response to GnRH, and the relative secretion of luteinizing hormone and follicle-stimulating hormone from the pituitary gonadotrope with subsequent direct effects on the ovary to produce a series of sex steroids and peptides that aid in the generation of a single mature oocyte and the preparation of a receptive endometrium for implantation to ensue. Any derailment along this programmed pathway can lead to an abnormal menstrual cycle with subsequent impact on the ability to conceive and maintain a pregnancy. This review contains 7 figures and 26 references Key words: follicle-stimulating hormone, follicular phase, gonadotropin-releasing hormone, luteal phase, luteinizing hormone, menstrual cycle, ovulation, progesterone, proliferative phase, secretory phase

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Effects of high levels of body condition and food intake on plasma follicle stimulating hormone, luteinizing hormone, prolactin and progesterone profiles around mating in Greyface ewes

Animal Science ◽

10.1017/s0003356100018377 ◽

1986 ◽

Vol 43 (1) ◽

pp. 101-107 ◽

Cited By ~ 13

Author(s):

S. M. Rhind ◽

I. D. Leslie ◽

R. G. Gunn ◽

J. M. Doney

Keyword(s):

Luteinizing Hormone ◽

Body Condition ◽

Luteal Phase ◽

Weight Maintenance ◽

Follicle Stimulating Hormone ◽

Live Weight ◽

Follicular Phase ◽

High Group ◽

High Level ◽

Stimulating Hormone

ABSTRACTTwo groups of 19 Border Leicester cf × Scottish Blackface 9 ewes were fed so that ewes of one group were in a very high level of body condition at mating (mean score 3·35) and had a high level of intake. Ewes of the second group were in moderately high condition (mean score 2·74) and were given a live-weight maintenance ration. Ewes in the high group had a higher ovulation rate than those of the moderate group (3·36 v. 2·33) but a lower number of embryos per ewe mated (1·16 v. 1·42). Mean follicle stimulating hormone profiles were similar for ewes of the two groups during the luteal and follicular phases of the cycle before mating and during the subsequent oestrus. Mean prolactin concentrations were higher in ewes of the high group during the follicular phase and oestrus but not during the luteal phase. Mean luteinizing hormone (LH) concentrations were higher in ewes of the high group during the follicular phase and oestrus but not during the luteal phase. Mean LH concentrations were similar for the two groups at all times but the frequency of LH pulses was higher in the high group during the follicular phase.Ewes that were not pregnant at slaughter had abnormal progesterone profiles following mating, abnormal pre-ovulatory LH surges or failed to show oestrus. These abnormalities were not related to gonadotrophin profiles prior to oestrus.

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