Laparoscopic Hepatic Resection: Do Favorable Short-Term Outcomes Make It the Procedure of Choice for Lesions of the Left Hemiliver?

2011 ◽  
Vol 140 (5) ◽  
pp. S-1035
Author(s):  
C. Kristian Enestvedt ◽  
Brian S. Diggs ◽  
Brett C. Sheppard ◽  
Susan L. Orloff ◽  
Kevin G. Billingsley
2019 ◽  
Vol 3 (5) ◽  
pp. 506-514
Author(s):  
Hiroji Shinkawa ◽  
Shogo Tanaka ◽  
Shigekazu Takemura ◽  
Ryosuke Amano ◽  
Kenjiro Kimura ◽  
...  

2020 ◽  
Vol 4 ◽  
pp. 18-18
Author(s):  
David Brough ◽  
Nicholas O’Rourke

2020 ◽  
pp. 1-8
Author(s):  
Geraldine Yanlei Lei ◽  
Liang Shen ◽  
Sameer P. Junnarkar ◽  
CheongWei Terence Huey ◽  
JeeKeem Low ◽  
...  

<b><i>Background/Purpose:</i></b> 90-day mortality is a key performance indicator for short-term perioperative outcome of hepatic resection (HR). Although many preoperative, intraoperative, and postoperative variables predict 90-day mortality following elective HR, only few are specific to hepatocellular carcinoma (HCC). This study aims to determine the predictors of 90-day mortality following elective HR for HCC. <b><i>Methods:</i></b> We report a retrospective analysis of patients who underwent elective HR between January 1, 2007, and December 31, 2017. Health status, perioperative variables, and the presence of post-hepatectomy liver failure (PHLF) were studied. Cox’s regression evaluated factors predicting 90-day mortality. <b><i>Results:</i></b> Two hundred and forty-four patients diagnosed with HCC underwent HR; 102 (41.8%) underwent a major HR. The postoperative 90-day mortality rate was 5.3%. Multivariate analysis demonstrated that Child-Pugh score (<i>p</i> &#x3c; 0.001), intraoperative blood loss (<i>p</i> = 0.013), the 50-50 criteria for PHLF (<i>p</i> &#x3c; 0.001) on postoperative day 5, and peak serum bilirubin &#x3e;119 µmol/L (<i>p</i> = 0.007) on postoperative day 3 predict 90-day mortality. <b><i>Conclusion:</i></b> In patients with HCC undergoing HR, Child-Pugh score, intraoperative blood loss, the 50-50 criteria for PHLF on postoperative day 5, and peak serum bilirubin &#x3e;119 µmol/L on postoperative day 3 predict 90-day mortality following elective HR for HCC.


2015 ◽  
Vol 55 (4) ◽  
pp. 291-301 ◽  
Author(s):  
Shogo Tanaka ◽  
Shigekazu Takemura ◽  
Hiroji Shinkawa ◽  
Takayoshi Nishioka ◽  
Genya Hamano ◽  
...  

Background/Purpose: Laparoscopic hepatic resection (LH) for hepatocellular carcinoma (HCC) has gradually gained ground as a safe and minimally invasive treatment, although LH for cirrhotic patients remains challenging. Methods: Between January 2007 and August 2014, 28 and 57 patients with histologically proven cirrhosis (histological activity index, fibrosis score 4) underwent pure LH and open hepatic resection (OH; less than segmentectomy), respectively, for peripheral HCC ≤5 cm. To correct the difference in clinicopathological factors, including difficulty scores, between the two groups, propensity score matching was used at a 1:1 ratio, which resulted in a comparison of 20 patients per group. We compared the short- and long-term outcomes of LH and OH to investigate the efficacy of LH. Results: Clinicopathological variables, including difficulty scores, were well balanced between the two groups. The incidence of complications and mean intraoperative blood loss were lower in the LH group than the OH group (0 vs. 45% and 180 vs. 440 ml, p = 0.001 and 0.04, respectively). The 3-year disease-free survival rate was 42% in the LH group and 30% in the OH group (p = 0.533), whereas the 5-year overall survival rates were 46 and 60%, respectively (p = 0.606). Conclusions: LH is a safe and effective treatment option for cirrhotic patients with HCC in terms of intraoperative blood loss and morbidity.


HPB ◽  
2011 ◽  
Vol 13 (7) ◽  
pp. 439-446 ◽  
Author(s):  
Peter D. Peng ◽  
Mark G. van Vledder ◽  
Susan Tsai ◽  
Mechteld C. de Jong ◽  
Martin Makary ◽  
...  

1995 ◽  
Vol 9 (12) ◽  
Author(s):  
M. Hashizume ◽  
K. Takenaka ◽  
K. Yanaga ◽  
M. Ohta ◽  
K. Kajiyama ◽  
...  

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