scholarly journals Genetical analysis for brain formation and function by gene targeting with mouse embryonic stem cells

1995 ◽  
Vol 67 ◽  
pp. 78
Author(s):  
Takeshi Yagi
Keyword(s):  
Stem Cells ◽  
Embryonic Stem Cells ◽  
Gene Targeting ◽  
Embryonic Stem ◽  
Mouse Embryonic Stem Cells ◽  
Genetical Analysis ◽  
And Function

scholarly journals Targeting frequency for deletion vectors in embryonic stem cells.

1994 ◽  
Vol 14 (4) ◽  
pp. 2404-2410 ◽  
Author(s):  
H Zhang ◽  
P Hasty ◽  
A Bradley
Keyword(s):  
Stem Cells ◽  
Embryonic Stem Cells ◽  
Gene Targeting ◽  
Embryonic Stem ◽  
Mouse Embryonic Stem Cells ◽  
Hypoxanthine Phosphoribosyltransferase ◽  
Genomic Deletions ◽  
Wide Range

We analyzed the gene targeting frequencies and recombination products generated by a series of replacement deletion vectors which target the hprt (hypoxanthine phosphoribosyltransferase) locus in mouse embryonic stem cells. We found that the targeting frequency of a 19.2-kb deletion was comparable to that of a 3-kb deletion or a conventional replacement event in which a 1.7-kb fragment was inserted into the locus. We also observed different integration patterns for these deletion vectors. A result of this finding is that a wide range of genomic deletions in embryonic stem cells is feasible.

scholarly journals Genome-Wide Identification of Targets and Function of Individual MicroRNAs in Mouse Embryonic Stem Cells

PLoS Genetics ◽  
2010 ◽  
Vol 6 (10) ◽  
pp. e1001163 ◽  
Author(s):  
Sophie A. Hanina ◽  
William Mifsud ◽  
Thomas A. Down ◽  
Katsuhiko Hayashi ◽  
Dónal O'Carroll ◽  
...  
Keyword(s):  
Stem Cells ◽  
Embryonic Stem Cells ◽  
Embryonic Stem ◽  
Mouse Embryonic Stem Cells ◽  
Genome Wide ◽  
And Function

scholarly journals Bi-allelic gene targeting in mouse embryonic stem cells

Methods ◽  
2011 ◽  
Vol 53 (4) ◽  
pp. 331-338 ◽  
Author(s):  
Peri H. Tate ◽  
William C. Skarnes
Keyword(s):  
Stem Cells ◽  
Embryonic Stem Cells ◽  
Gene Targeting ◽  
Embryonic Stem ◽  
Mouse Embryonic Stem Cells ◽  
Allelic Gene

scholarly journals Optimized Vector for Conditional Gene Targeting in Mouse Embryonic Stem Cells

BioTechniques ◽  
2003 ◽  
Vol 34 (6) ◽  
pp. 1136-1140 ◽  
Author(s):  
Marcus Conrad ◽  
Markus Brielmeier ◽  
Wolfgang Wurst ◽  
Georg W. Bornkamm
Keyword(s):  
Stem Cells ◽  
Embryonic Stem Cells ◽  
Gene Targeting ◽  
Embryonic Stem ◽  
Mouse Embryonic Stem Cells ◽  
Conditional Gene Targeting
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