Modification of a free Fe-S cluster cysteine residue in the active iron-responsive element-binding protein prevents RNA binding.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)46750-0 ◽

1993 ◽

Vol 268 (24) ◽

pp. 17655-17658

Author(s):

C.C. Philpott ◽

D. Haile ◽

T.A. Rouault ◽

R.D. Klausner

Keyword(s):

Rna Binding ◽

Binding Protein ◽

Cysteine Residue ◽

Iron Responsive Element ◽

Active Iron ◽

Element Binding Protein ◽

Responsive Element

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Localization of an RNA binding element of the iron responsive element binding protein within a proteolytic fragment containing iron coordination ligands

Nucleic Acids Research ◽

10.1093/nar/22.13.2627 ◽

1994 ◽

Vol 22 (13) ◽

pp. 2627-2633 ◽

Author(s):

Greg R. Swenson ◽

William E. Walden

Keyword(s):

Rna Binding ◽

Binding Protein ◽

Proteolytic Fragment ◽

Iron Responsive Element ◽

Element Binding Protein ◽

Iron Coordination ◽

Responsive Element

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Overexpression of Iron-Responsive Element-Binding Protein and Its Analytical Characterization as the RNA-Binding Form, Devoid of an Iron-Sulfur Cluster

Archives of Biochemistry and Biophysics ◽

10.1006/abbi.1994.1270 ◽

1994 ◽

Vol 311 (2) ◽

pp. 517-522 ◽

Author(s):

J.P. Basilion ◽

M.C. Kennedy ◽

H. Beinert ◽

C.M. Massinople ◽

R.D. Klausner ◽

...

Keyword(s):

Rna Binding ◽

Binding Protein ◽

Iron Sulfur Cluster ◽

Analytical Characterization ◽

Sulfur Cluster ◽

Iron Responsive Element ◽

Iron Sulfur ◽

Element Binding Protein ◽

Responsive Element

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Reciprocal control of RNA-binding and aconitase activity in the regulation of the iron-responsive element binding protein: role of the iron-sulfur cluster.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.89.16.7536 ◽

1992 ◽

Vol 89 (16) ◽

pp. 7536-7540 ◽

Author(s):

D. J. Haile ◽

T. A. Rouault ◽

C. K. Tang ◽

J. Chin ◽

J. B. Harford ◽

...

Keyword(s):

Rna Binding ◽

Binding Protein ◽

Iron Sulfur Cluster ◽

Sulfur Cluster ◽

Aconitase Activity ◽

Iron Responsive Element ◽

Iron Sulfur ◽

Element Binding Protein ◽

Responsive Element

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Cellular regulation of the iron-responsive element binding protein: disassembly of the cubane iron-sulfur cluster results in high-affinity RNA binding.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.89.24.11735 ◽

1992 ◽

Vol 89 (24) ◽

pp. 11735-11739 ◽

Author(s):

D. J. Haile ◽

T. A. Rouault ◽

J. B. Harford ◽

M. C. Kennedy ◽

G. A. Blondin ◽

...

Keyword(s):

Rna Binding ◽

Binding Protein ◽

Cellular Regulation ◽

Iron Sulfur Cluster ◽

Sulfur Cluster ◽

High Affinity ◽

Iron Responsive Element ◽

Iron Sulfur ◽

Element Binding Protein ◽

Responsive Element

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The iron-responsive element binding protein: a method for the affinity purification of a regulatory RNA-binding protein.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.86.15.5768 ◽

1989 ◽

Vol 86 (15) ◽

pp. 5768-5772 ◽

Author(s):

T. A. Rouault ◽

M. W. Hentze ◽

D. J. Haile ◽

J. B. Harford ◽

R. D. Klausner

Keyword(s):

Rna Binding ◽

Binding Protein ◽

Affinity Purification ◽

Protein A ◽

Rna Binding Protein ◽

Regulatory Rna ◽

Iron Responsive Element ◽

Element Binding Protein ◽

Responsive Element

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The iron-responsive element-binding protein: localization of the RNA-binding site to the aconitase active-site cleft.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.91.2.574 ◽

1994 ◽

Vol 91 (2) ◽

pp. 574-578 ◽

Author(s):

J. P. Basilion ◽

T. A. Rouault ◽

C. M. Massinople ◽

R. D. Klausner ◽

W. H. Burgess

Keyword(s):

Binding Site ◽

Active Site ◽

Rna Binding ◽

Binding Protein ◽

Protein Localization ◽

Iron Responsive Element ◽

Active Site Cleft ◽

Element Binding Protein ◽

Responsive Element

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Iron-responsive element-binding protein. Phosphorylation by protein kinase C.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)74258-6 ◽

1993 ◽

Vol 268 (36) ◽

pp. 27363-27370

Author(s):

R S Eisenstein ◽

P T Tuazon ◽

K L Schalinske ◽

S A Anderson ◽

J A Traugh

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Protein Phosphorylation ◽

Binding Protein ◽

Iron Responsive Element ◽

Kinase C ◽

Element Binding Protein ◽

Responsive Element

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Iron regulates the activity of the iron-responsive element binding protein without changing its rate of synthesis or degradation.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)35789-2 ◽

1992 ◽

Vol 267 (34) ◽

pp. 24466-24470 ◽

Author(s):

C.K. Tang ◽

J Chin ◽

J.B. Harford ◽

R.D. Klausner ◽

T.A. Rouault

Keyword(s):

Binding Protein ◽

Iron Responsive Element ◽

Element Binding Protein ◽

Responsive Element

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Sequence and expression of the murine iron-responsive element binding protein

Nucleic Acids Research ◽

10.1093/nar/19.22.6333 ◽

1991 ◽

Vol 19 (22) ◽

pp. 6333-6333 ◽

Author(s):

Caroline C. Philpott ◽

Tracey A. Rouault ◽

Richard D. Klausner

Keyword(s):

Binding Protein ◽

Iron Responsive Element ◽

Element Binding Protein ◽

Responsive Element

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Molecular characterization of a second iron-responsive element binding protein, iron regulatory protein 2. Structure, function, and post-translational regulation.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)47367-x ◽

1994 ◽

Vol 269 (49) ◽

pp. 30904-30910

Author(s):

F Samaniego ◽

J Chin ◽

K Iwai ◽

T A Rouault ◽

R D Klausner

Keyword(s):

Structure Function ◽

Molecular Characterization ◽

Translational Regulation ◽

Binding Protein ◽

Regulatory Protein ◽

Iron Regulatory Protein ◽

Iron Responsive Element ◽

Element Binding Protein ◽

Responsive Element

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