scholarly journals Analysis of an invariant cofactor-protein interaction in thiamin diphosphate-dependent enzymes by site-directed mutagenesis. Glutamic acid 418 in transketolase is essential for catalysis.

1994 ◽  
Vol 269 (51) ◽  
pp. 32144-32150
Author(s):  
C Wikner ◽  
L Meshalkina ◽  
U Nilsson ◽  
M Nikkola ◽  
Y Lindqvist ◽  
...  
Keyword(s):  
Glutamic Acid ◽  
Protein Interaction ◽  
Site Directed Mutagenesis ◽  
Directed Mutagenesis ◽  
Thiamin Diphosphate

scholarly journals Site-directed mutagenesis of active-site-related residues inTorpedoacetylcholinesterase Presence of a glutamic acid in the catalytic triad

FEBS Letters ◽  
1992 ◽  
Vol 309 (3) ◽  
pp. 421-423 ◽  
Author(s):  
Nathalie Duval ◽  
Suzanne Bon ◽  
Israel Silman ◽  
Joel Sussman ◽  
Jean Massoulié
Keyword(s):  
Glutamic Acid ◽  
Active Site ◽  
Catalytic Triad ◽  
Site Directed Mutagenesis ◽  
Directed Mutagenesis

scholarly journals Examination of the Thiamin Diphosphate Binding Site in Yeast Transketolase by Site-Directed Mutagenesis

1997 ◽  
Vol 244 (2) ◽  
pp. 646-652 ◽  
Author(s):  
Ludmilla Meshalkina ◽  
Ulrika Nilsson ◽  
Christer Wikner ◽  
Tatiana Kostikowa ◽  
Gunter Schneider
Keyword(s):  
Binding Site ◽  
Site Directed Mutagenesis ◽  
Directed Mutagenesis ◽  
Thiamin Diphosphate
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