scholarly journals THE ANTIGENIC STRUCTURE OF HEMOLYTIC STREPTOCOCCI OF LANCEFIELD GROUP A

1942 ◽  
Vol 142 (2) ◽  
pp. 823-833
Author(s):  
Charles A. Zittle ◽  
Tzvee N. Harris
Keyword(s):  
Antigenic Structure ◽  
Group A ◽  
Lancefield Group

scholarly journals Evaluation of a two-minute strep A direct swab test (SADST) on patients with pharyngitis at a primary care clinic

1986 ◽  
Vol 97 (1) ◽  
pp. 133-138 ◽  
Author(s):  
G. F. Araj ◽  
H. A. Majeed
Keyword(s):  
Primary Care ◽  
Primary Care Clinic ◽  
Culture Method ◽  
Care Clinic ◽  
Predictive Values ◽  
Primary Care Clinics ◽  
Clinical Laboratories ◽  
Standard Culture ◽  
Group A ◽  
Lancefield Group

SUMMARYA two-minute strep A direct swab test (SADST) was used to detect the presence of Lancefield group A streptococci (GAS) from the throats of 207 patients with pharyngitis at a primary-care clinic. The results were compared with a standard culture method. Fifty-one specimens were positive and 156 specimens were negative for GAS by culture. The SADST had a sensitivity of 96% (49 of 51) and specificity of 98·7% (154 of 156). The predictive values of a positive and negative SADST, for GAS, were 96% and 98·7 % respectively. The SADST showed negative reactions with five specimens containing beta-haemotytic streptococci other than GAS and 34 known stock cultures other than GAS. Our results indicate that SADST is a rapid, simple, convenient and reliable test to use for diagnosis of GAS pharyngitis at primary care clinics, physicians' offices and clinical laboratories.

scholarly journals Milk epidemic of angina, originating from a Cow with mastitis and due to Streptococcus pyogenes (Lancefield group A)

1938 ◽  
Vol 38 (3) ◽  
pp. 384-391 ◽  
Author(s):  
E. Juel Henningsen ◽  
J. Ernst
Keyword(s):  
Sore Throat ◽  
Streptococcus Pyogenes ◽  
Raw Milk ◽  
Slight Degree ◽  
Group A ◽  
The Village ◽  
Lancefield Group

A report is given of a milk epidemic of septic sore throat, comprising about 100 cases.The epidemic originated from a cow with a slight degree of mastitis, produced by a Streptococcus pyogenes (Lancefield's group A).The same Streptococcus (which we did not succeed in typing) was isolated from 74% of the patients examined and from three persons who were handling the milk.It seems reasonable to assume that the cow was infected from the milkers. Owing to particular conditions in the distribution of the raw milk, it is possible that the milk delivered raw in the village involved on one day a massive contamination.The epidemic is characterized as moderately severe. No case terminated fatally.

Severe Peritonitis during CAPD Due to Beta-hemolytic Streptococcus, Lancefield Group A

1983 ◽  
Vol 3 (2) ◽  
pp. 109-109 ◽  
Author(s):  
C. Dadone ◽  
L. Bonoldi ◽  
G. Giltri ◽  
L. Vigore ◽  
P. Mariani ◽  
...  
Keyword(s):  
Hemolytic Streptococcus ◽  
Beta Hemolytic Streptococcus ◽  
Severe Peritonitis ◽  
Group A ◽  
Lancefield Group

Streptococci and the Genital Tract

1993 ◽  
Vol 4 (2) ◽  
pp. 63-66 ◽  
Author(s):  
D Rowen
Keyword(s):  
Genital Tract ◽  
Neonatal Infection ◽  
Symptomatic Infection ◽  
Optimal Drug ◽  
Drug Regimens ◽  
Group A ◽  
Normal Women ◽  
Group B ◽  
Term Labour ◽  
Lancefield Group

Streptococci of Lancefield Group B (GBS) are known to cause maternal sepsis and neonatal infection, whereas streptococci Lancefield Group A (GAS) cause vulvo-vaginitis in both children and adults. Prevalence of SGB colonization of the lower genital tract of normal women is between 4–18%, with higher rates found in hospital personnel and delivery rooms. Such high carriage rates may be a significant factor in nosocomial transmission of GBS to neonates. Symptomatic infection is uncommon and usually secondary to other pathological states. Amnionitis is a complication of vaginal carriage of GBS and there is now evidence that chorioamnionitis is associated with pre-term labour and its attendant problems. GBS infection of the male genitalia has also been described. Intrapartum chemoprophylaxis has been shown to prevent early onset GBS disease of the neonate. Prevalence of GAS in the genital tract is lower than that for GBS, but is more likely to be symptomatic. The response to penicillin is usually prompt. Optimal drug regimens need to be determined, particularly for use in pregnancy.

ERYTHROMYCIN CONCENTRATIONS IN MIDDLE EAR EXUDATES

PEDIATRICS ◽  
1971 ◽  
Vol 48 (3) ◽  
pp. 417-422 ◽  
Author(s):  
James W. Bass ◽  
Russell W. Steele ◽  
Robert A. Wiebe ◽  
Edwin P. Dierdorff
Keyword(s):  
Otitis Media ◽  
Middle Ear ◽  
Acute Otitis Media ◽  
Needle Aspiration ◽  
Highly Effective ◽  
Group A ◽  
Lancefield Group

Children with acute otitis media were treated with oral esters of erythromycin in doses of 12.5 mg/kg at 6-hour intervals for 24 hours (50 mg/kg/day). Two hours after the last dose serum and middle ear exudates obtained by needle aspiration were assayed for erythromycin levels. Gram stained smears and cultures of the middle ear exudates were obtained and correlated with the levels of erythromycin found in the exudates. Concentrations of the drug were found in middle ear exudates sufficient to be effective against essentially all strains of D. pneumoniae and Lancefield Group A beta hemolytic streptococci. These results may explain why erythromycin is highly effective in the treatment of acute otitis media due to these organisms. Penetration of erythromycin into middle ear exudates may not be sufficient in some cases to eradicate all strains of H. inflenzae and therefore otitis media due to this organism may not respond as readily to therapy with this agent.

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