scholarly journals A MICROBIOLOGICAL METHOD FOR THE DETERMINATION OF p-AMINOBENZOIC ACID

1942 ◽  
Vol 146 (1) ◽  
pp. 109-114
Author(s):  
Maurice Landy ◽  
Dorothy M. Dicken
Author(s):  
Hind Hadi ◽  
Gufran Salim

A simple, rapid and sensitive spectrophotmetric method for trace determination of salbutamol (SAL) in aqueous solution and in pharmaceutical preparations is described. The method is based on the diazotization coupling reaction of the intended compound with 4-amino benzoic acid (ABA) in alkaline medium to form an intense orange, water soluble dye that is stable and shows maximum absorption at 410 nm. A graph of absorbance versus concentration indicates that Beer’s law is obeyed over the concentration range of 0.5-30 ppm, with a molar absorbtivity 3.76×104 L.mol-1 .cm-1 depending on the concentration of SAL. The optimum conditions and stability of the colored product have been investigated and the method was applied successfully to the determination of SAL in dosage forms.


1941 ◽  
Vol 139 (2) ◽  
pp. 675-686 ◽  
Author(s):  
Esmond E. Snell ◽  
Lemuel D. Wright

2007 ◽  
Vol 847 (2) ◽  
pp. 224-230 ◽  
Author(s):  
Mugunthu R. Dhananjeyan ◽  
Crystal Bykowski ◽  
Jill A. Trendel ◽  
Jeffrey G. Sarver ◽  
Howard Ando ◽  
...  

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