Suppression of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase Activity and Inhibition of Growth of Human Fibroblasts by 7-Ketocholesterol

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)42106-6 ◽

1974 ◽

Vol 249 (22) ◽

pp. 7306-7314 ◽

Author(s):

Michael S. Brown ◽

Joseph L. Goldstein

Keyword(s):

Reductase Activity ◽

Human Fibroblasts ◽

Inhibition Of Growth ◽

Coenzyme A Reductase

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Regulation of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Activity in Human Fibroblasts by Lipoproteins

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.70.7.2162 ◽

1973 ◽

Vol 70 (7) ◽

pp. 2162-2166 ◽

Author(s):

M. S. Brown ◽

S. E. Dana ◽

J. L. Goldstein

Keyword(s):

Reductase Activity ◽

Human Fibroblasts ◽

Coenzyme A Reductase

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Regulation of 3-hydroxy-3-methylglutaryl coenzyme a reductase activity in human fibroblasts by reversible phosphorylation: Modulation of enzymatic activity by low density lipoprotein, sterols, and mevalonolactone

Archives of Biochemistry and Biophysics ◽

10.1016/0003-9861(86)90120-7 ◽

1986 ◽

Vol 244 (1) ◽

pp. 310-322 ◽

Author(s):

Zafarul H. Beg ◽

Diane C. Reznikov ◽

Joel Avigan

Keyword(s):

Enzymatic Activity ◽

Reductase Activity ◽

Low Density Lipoprotein ◽

Human Fibroblasts ◽

Density Lipoprotein ◽

Low Density ◽

Reversible Phosphorylation ◽

Coenzyme A Reductase

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Regulation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase Activity in Cultured Human Fibroblasts

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)42998-0 ◽

1974 ◽

Vol 249 (3) ◽

pp. 789-796 ◽

Author(s):

Michael S. Brown ◽

Suzanna E. Dana ◽

Joseph L. Goldstein

Keyword(s):

Reductase Activity ◽

Human Fibroblasts ◽

Cultured Human Fibroblasts ◽

Coenzyme A Reductase

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Induction of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in human fibroblasts incubated with compactin (ML-236B), a competitive inhibitor of the reductase

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)38120-6 ◽

1978 ◽

Vol 253 (4) ◽

pp. 1121-1128 ◽

Author(s):

M.S. Brown ◽

J.R. Faust ◽

J.L. Goldstein ◽

I. Kaneko ◽

A. Endo

Keyword(s):

Reductase Activity ◽

Human Fibroblasts ◽

Competitive Inhibitor ◽

Coenzyme A Reductase

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The role of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in the regulation of ubiquinone synthesis in human fibroblasts.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)70714-5 ◽

1980 ◽

Vol 255 (12) ◽

pp. 5894-5899 ◽

Author(s):

A.M. Nambudiri ◽

S. Ranganathan ◽

H. Rudney

Keyword(s):

Reductase Activity ◽

Human Fibroblasts ◽

Coenzyme A Reductase

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Effects of platelet-derived growth factor on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in cultured human fibroblasts.

Arteriosclerosis An Official Journal of the American Heart Association Inc ◽

10.1161/01.atv.6.1.34 ◽

1986 ◽

Vol 6 (1) ◽

pp. 34-41 ◽

Author(s):

K P Fairbanks ◽

L D Witte ◽

D S Goodman

Keyword(s):

Growth Factor ◽

Reductase Activity ◽

Human Fibroblasts ◽

Platelet Derived Growth Factor ◽

Cultured Human Fibroblasts ◽

Coenzyme A Reductase

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Cholesterol, 7-ketocholesterol and 25-hydroxycholesterol uptake studies and effect on 3-hydroxy-3-methylglutaryl-coenzyme a reductase activity in human fibroblasts

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism ◽

10.1016/0005-2760(75)90165-4 ◽

1975 ◽

Vol 398 (1) ◽

pp. 10-17 ◽

Author(s):

Jan L. Breslowa ◽

David A. Lothrop ◽

Duane R. Spaulding ◽

Andrew A. Kandutsch

Keyword(s):

Reductase Activity ◽

Human Fibroblasts ◽

Uptake Studies ◽

Coenzyme A Reductase

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Inhibitors of sterol synthesis. Chemical synthesis and spectral properties of 3 beta-hydroxy-5 alpha-cholesta-8(14),24-dien-15-one, 3 beta,25-dihydroxy-5 alpha-cholest-8(14)-en-15-one, and 3 beta,24-dihydroxy-5 alpha-cholest-8(14)-en-15-one and their effects on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in CHO-K1 cells.

The Journal of Lipid Research ◽

10.1016/s0022-2275(20)41405-1 ◽

1992 ◽

Vol 33 (10) ◽

pp. 1503-1515

Author(s):

S Swaminathan ◽

FD Pinkerton ◽

S Numazawa ◽

WK Wilson ◽

GJ Schroepfer

Keyword(s):

Chemical Synthesis ◽

Spectral Properties ◽

Reductase Activity ◽

Sterol Synthesis ◽

Coenzyme A Reductase

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Influence of follicular maturation on 3-hydroxy-methylglutaryl coenzyme A reductase activity in hen granulosa cells

Reproduction ◽

10.1530/jrf.0.0790215 ◽

1987 ◽

Vol 79 (1) ◽

pp. 215-221 ◽

Author(s):

E. K. Asem ◽

F. Hertelendy

Keyword(s):

Granulosa Cells ◽

Reductase Activity ◽

Follicular Maturation ◽

Coenzyme A Reductase

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Inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in hepatoma tissue culture cells by pure cholesterol and several cholesterol derivatives. Evidence supporting two distinct mechanisms.20l.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)33712-2 ◽

1976 ◽

Vol 251 (6) ◽

pp. 1745-1758 ◽

Author(s):

J J Bell ◽

T E Sargeant ◽

J A Watson

Keyword(s):

Tissue Culture ◽

Reductase Activity ◽

Culture Cells ◽

Tissue Culture Cells ◽

Pure Cholesterol ◽

Hepatoma Tissue ◽

Coenzyme A Reductase

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