scholarly journals Photoaffinity labeling of a mitochondrial hydrophobic protein by an anisotropic inhibitor of energy transduction in oxidative phosphorylation.

1981 ◽  
Vol 256 (19) ◽  
pp. 9855-9860
Author(s):  
T. Higuti ◽  
T. Ohe ◽  
N. Arakaki ◽  
Y. Kotera
2015 ◽  
Vol 40 (1) ◽  
Author(s):  
Mohazabeh Ghafuri ◽  
Mohsen Nosrati ◽  
Saman Hosseinkhani

AbstractAdenosine triphosphate (ATP) production in living cells is very important. Different researches have shown that in terms of mathematical modeling, the domain of these investigations is essentially restricted. Recently the thermodynamic models have been suggested for calculation of the efficiency of oxidative phosphorylation process and rate of energy loss in animal cells using chemiosmotic theory and non-equilibrium thermodynamics equations. In our previous work, we developed a mathematical model for mitochondria of animal cells. In this research, according to similarities between oxidative phosphorylation process in microorganisms and animal cells, Golfar's model was developed to predict the non-equilibrium thermodynamic behavior of the oxidative phosphorylation process for bacteria in aerobic condition. With this model the rate of energy loss,


Author(s):  
FAUSTO RAMIREZ ◽  
SHU-I TU ◽  
PRABHA R. CHATTERJI ◽  
HIROSHI OKAZAKI ◽  
JAMES F. MARECEK ◽  
...  

Author(s):  
Mohazabeh Ghafuri ◽  
Bahareh Golfar ◽  
Mohsen Nosrati ◽  
Saman Hoseinkhani

AbstractThe process of ATP production is one of the most vital processes in living cells which happens with a high efficiency. Thermodynamic evaluation of this process and the factors involved in oxidative phosphorylation can provide a valuable guide for increasing the energy production efficiency in research and industry. Although energy transduction has been studied qualitatively in several researches, there are only few brief reviews based on mathematical models on this subject. In our previous work, we suggested a mathematical model for ATP production based on non-equilibrium thermodynamic principles. In the present study, based on the new discoveries on the respiratory chain of animal mitochondria, Golfar's model has been used to generate improved results for the efficiency of oxidative phosphorylation and the rate of energy loss. The results calculated from the modified coefficients for the proton pumps of the respiratory chain enzymes are closer to the experimental results and validate the model.


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