C0162: Procoagulant Phospolipid Activity in Microparticles is Associated to Cardiovascular Risk Factors and Disease Severity in Peripheral Artery Disease

2014 ◽  
Vol 133 ◽  
pp. S94
Author(s):  
C. Roncal Mancho ◽  
E. Martinez-Aguilar ◽  
V. Gomez-Rodriguez ◽  
L. Fernadez-Alonso ◽  
J. Antonio Rodriguez ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Disease Severity ◽  
Peripheral Artery Disease ◽  
Peripheral Artery ◽  
Artery Disease

Study Of Cardiovascular Risk Factors In Patients With Peripheral Artery Disease

2019 ◽  
Vol 287 ◽  
pp. e190
Author(s):  
A. Ceasovschih ◽  
V. Sorodoc ◽  
V. Aursulesei ◽  
D. Tesloianu ◽  
I.M. Jaba ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Peripheral Artery Disease ◽  
Peripheral Artery ◽  
Artery Disease

scholarly journals Epidemiology of peripheral artery disease in Palestine

VASA ◽  
2020 ◽  
Vol 49 (4) ◽  
pp. 323-329
Author(s):  
Amal Jamee ◽  
Victor Aboyans ◽  
Julien Magne ◽  
Mohammed Elhendy ◽  
Pierre Marie Preux ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Peripheral Artery Disease ◽  
Ankle Brachial Index ◽  
Arab Countries ◽  
Multivariate Logistic Regression Model ◽  
Peripheral Artery ◽  
High Prevalence ◽  
Artery Disease

Summary: Background: Peripheral artery disease (PAD) is one of the most common manifestations of atherosclerosis affecting more than 200 million people globally but little is known about its epidemiology in Middle East populations, particularly in Arab countries. The present study was undertaken to assess the prevalence of PAD in the general population aged 40 years and more in Gaza-Palestine, and to determine the prevalence of its associated risk factors. Patients and methods: The study design was a cross-sectional with a stratified proportional sampling, involving the five governorates in Gaza Strip. We selected 1490 individuals aged age ≥ 40 years living in the area for more than 3 years. The questionnaire on lifestyle and cardiovascular risk factors was applied and the ankle-brachial index (ABI) was measured by Doppler examination in both legs in all participants. PAD was defined as an ABI ≤ 0.90. We excluded 92 participants (6 %) because of missing ABI or ABI > 1.40. Results: One-half of the 1398 participants had at least two associated cardiovascular risk factors, one-third were on aspirin and 15 % on statins. Overall, we found PAD in 191 (13.7 %) cases. This prevalence increased with age, and 18.7 % of adults older than 65 years had PAD. The prevalence was higher in females than in males (respectively 15.6 % vs 11.6 % p = 0.031). In the multivariate logistic regression model, significant associated factors with PAD in males were CAD (OR: 3.5; 95 % CI: 1.4–8.6), hypertension (OR: 2.8; 95 % CI: 1.3–6.1), and current smoking (OR: 2.7; 95 % CI: 1.1–6.6). In women, hypertension remains the main associated risk factor. Conclusions: Our study highlights the high prevalence of PAD in the Gazan community, mostly related to the high prevalence of cardiovascular risk factors and other cardiovascular conditions.

scholarly journals Impact of cardiovascular risk factors on severity of peripheral artery disease

2015 ◽  
Vol 242 (1) ◽  
pp. 97-101 ◽  
Author(s):  
Thomas R. Wyss ◽  
Luise Adam ◽  
Alan G. Haynes ◽  
Nils Kucher ◽  
Guenther Silbernagel ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Peripheral Artery Disease ◽  
Peripheral Artery ◽  
Artery Disease

scholarly journals Peripheral Artery Disease and Cardiovascular Risk Factors in the Elderly

1996 ◽  
Vol 16 (12) ◽  
pp. 1495-1500 ◽  
Author(s):  
J. David Curb ◽  
Kamal Masaki ◽  
Beatriz L. Rodriguez ◽  
Robert D. Abbott ◽  
Cecil M. Burchfiel ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Peripheral Artery Disease ◽  
The Elderly ◽  
Peripheral Artery ◽  
Artery Disease

scholarly journals Associations Between Conventional Cardiovascular Risk Factors and Risk of Peripheral Artery Disease in Men

JAMA ◽  
2012 ◽  
Vol 308 (16) ◽  
pp. 1660 ◽  
Author(s):  
Michel M. Joosten ◽  
Jennifer K. Pai ◽  
Monica L. Bertoia ◽  
Eric B. Rimm ◽  
Donna Spiegelman ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Peripheral Artery Disease ◽  
Peripheral Artery ◽  
Artery Disease

scholarly journals Prevalence of visceral artery involvement in patients with peripheral artery disease found on run-off MRA

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Felix Streckenbach ◽  
Felix G. Meinel ◽  
Felix Ammermann ◽  
Anke Busse ◽  
Andreas Neumann ◽  
...  
Keyword(s):  
Risk Factors ◽  
Renal Function ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Peripheral Artery Disease ◽  
Visceral Artery ◽  
Peripheral Artery ◽  
Run Off ◽  
Artery Disease ◽  
Fontaine Stage

Abstract Background In patients with peripheral artery disease (PAD), run-off MR-angiography (MRA) is a commonly performed diagnostic test to obtain high-resolution images for evaluation of the arterial system from the aorta through the distal run-off vessels. The aim of this study was to investigate the prevalence of visceral artery involvement (VAI) in patients with PAD and leg symptoms examined with run-off MRA. Methods We retrospectively analyzed 145 patients (median age 68 years, range 27–91) who underwent MRA due to known or suspected PAD at our institution between 2012 and 2018. MRA examinations were re-evaluated for visceral artery stenosis. Patient dossiers were reviewed to determine cardiovascular risk factors, kidney function and Fontaine stage of PAD. Results Involvement of at least one visceral artery with ≥ 50% diameter stenosis was found in 72 (50%) patients. There were no differences in age, gender, MRA indication, Fontaine stage, levels of C-reactive protein (CRP), cardiovascular risk factors or vascular comorbidities between patients with and without VAI. Renal artery (RA) involvement with ≥ 50% diameter stenosis was observed in 28 (20%) of patients. Patients with involvement of the RA were more likely to suffer from hypertension (79 vs. 54%, p = 0.019) and reduced renal function (glomerular filtration rate 70 vs. 88 mL/min/1.73m2, p = 0.014). Conclusion Visceral artery stenosis can be seen in half of patients with known or suspected PAD and leg symptoms on run-off MRA. Investigating for RA stenosis in patients with PAD and hypertension and/or impaired renal function may have high diagnostic yield.

scholarly journals Diabetes mellitus and other cardiovascular risk factors in lower-extremity peripheral artery disease versus coronary artery disease: an analysis of 1,121,359 cases from the nationwide databases

2019 ◽  
Vol 18 (1) ◽  
Author(s):  
Mitsuyoshi Takahara ◽  
◽  
Osamu Iida ◽  
Shun Kohsaka ◽  
Yoshimitsu Soga ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Coronary Artery Disease ◽  
Cardiovascular Risk ◽  
Coronary Artery ◽  
Lower Extremity ◽  
Cardiovascular Risk Factors ◽  
Clinical Profile ◽  
Peripheral Artery ◽  
Artery Disease

Abstract Background Lower-extremity peripheral artery disease (LE-PAD) and coronary artery disease (CAD) are both pathologically rooted in atherosclerosis, and their shared clinical features regarding the exposure to cardiovascular risk factors have been emphasized. However, comparative data of the two cardiovascular diseases (CVDs) were so far lacking. The purpose of this study was to directly compare the clinical profile between cases undergoing endovascular therapy (EVT) for LE-PAD and those undergoing percutaneous coronary intervention (PCI). Methods Data were extracted from the nationwide procedural databases of EVT and PCI in Japan (J-EVT and J-PCI) between 2012 and 2017. A total of 1,121,359 cases (103,887 EVT cases for critical limb ischemia [CLI] or intermittent claudication and 1,017,472 PCI cases for acute coronary syndrome [ACS] or stable angina) were analyzed. Heterogeneity in clinical profile between CVDs was evaluated using the C statistic of the logistic regression model for which dependent variable was one CVD versus another, and explanatory variables were clinical profile. When two CVDs were completely discriminated from each other by the developed model, the C statistic (discrimination ability) of the model would be equal to 1, indicating that the two CVDs were completely different in clinical profile. On the other hand, when two CVDs were identical in clinical profile, the developed model would not discriminate them at all, with the C statistic equal to 0.5. Results Mean age was 73.5 ± 9.3 years in LE-PAD patients versus 70.0 ± 11.2 years in CAD patients (P < 0.001). The prevalence of diabetes mellitus and end-stage renal disease was 1.96- and 6.39-times higher in LE-PAD patients than in CAD patients (both P < 0.001). The higher prevalence was observed irrespective of age group. The exposure to other cardiovascular risk factors and the likelihood of cardiovascular risk clustering also varied between the diseases. The between-disease heterogeneity in patient profile was particularly evident between CLI and ACS, with the C statistic equal to 0.833 (95% CI 0.831–0.836). Conclusions The current study, an analysis based on nationwide procedural databases, confirmed that patient profiles were not identical but rather considerably different between clinically significant LE-PAD and CAD warranting revascularization.

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