Gastrointestinal symptoms related to autonomic dysfunction following spinal cord injury

Author(s):  
Eric A.L. Chung ◽  
Anton V. Emmanuel
2020 ◽  
Vol 15 (6) ◽  
pp. 522-530
Author(s):  
Jiawei Shu ◽  
Feng Cheng ◽  
Zhe Gong ◽  
Liwei Ying ◽  
Chenggui Wang ◽  
...  

Spinal cord injury (SCI) is different from peripheral nerve injury; it results in devastating and permanent damage to the spine, leading to severe motor, sensory and autonomic dysfunction. SCI produces a complex microenvironment that can result in hemorrhage, inflammation and scar formation. Not only does it significantly limit regeneration, but it also challenges a multitude of transplantation strategies. In order to promote regeneration, researchers have recently begun to focus their attention on strategies that manipulate the complicated microenvironment produced by SCI. And some have achieved great therapeutic effects. Hence, reconstructing an appropriate microenvironment after transplantation could be a potential therapeutic solution for SCI. In this review, first, we aim to summarize the influential compositions of the microenvironment and their different effects on regeneration. Second, we highlight recent research that used various transplantation strategies to modulate different microenvironments produced by SCI in order to improve regeneration. Finally, we discuss future transplantation strategies regarding SCI.


2010 ◽  
Vol 89 (10) ◽  
pp. 824-830 ◽  
Author(s):  
Evren Yasar ◽  
Bilge Yilmaz ◽  
Ayse Saatci Yasar ◽  
Ahmet Salim Goktepe ◽  
Ridvan Alaca ◽  
...  

2005 ◽  
Vol 48 (8) ◽  
pp. 1562-1568 ◽  
Author(s):  
Clinton Ng ◽  
Gillian Prott ◽  
Susan Rutkowski ◽  
Yueming Li ◽  
Ross Hansen ◽  
...  

2014 ◽  
Vol 31 (18) ◽  
pp. 1531-1539 ◽  
Author(s):  
Michael J. Berger ◽  
Michèle Hubli ◽  
Andrei V. Krassioukov

Spinal Cord ◽  
1984 ◽  
Vol 22 (3) ◽  
pp. 198-198
Author(s):  
S L Stover ◽  
Vinod Sahgal ◽  
Renate E Gay

Sign in / Sign up

Export Citation Format

Share Document