A critical appraisal of the rate pressure product as index of myocardial oxygen consumption for the study of metabolic coronary flow regulation

1999 ◽  
Vol 71 (2) ◽  
pp. 141-148 ◽  
Author(s):  
Jasper E. Kal ◽  
Harry B. Van Wezel ◽  
Isabelle Vergroesen
Keyword(s):  
Oxygen Consumption ◽  
Coronary Flow ◽  
Myocardial Oxygen Consumption ◽  
Critical Appraisal ◽  
Flow Regulation ◽  
Rate Pressure Product ◽  
Coronary Flow Regulation

Rate-pressure product and myocardial oxygen consumption during surgery for coronary artery bypass.

Circulation ◽  
1979 ◽  
Vol 60 (2) ◽  
pp. 170-173 ◽  
Author(s):  
P L Wilkinson ◽  
J R Moyers ◽  
T Ports ◽  
K Chatterjee ◽  
D Ullyott ◽  
...  
Keyword(s):  
Oxygen Consumption ◽  
Coronary Artery ◽  
Coronary Artery Bypass ◽  
Myocardial Oxygen Consumption ◽  
Artery Bypass ◽  
Rate Pressure Product

Central Neural Aspects of Coronary Flow Regulation

2020 ◽  
pp. 249-263
Author(s):  
D. D. Gutterman ◽  
A. C. Bonham ◽  
J. M. Arthur ◽  
J. E. Stuhlmuller ◽  
G. F. Gebhart ◽  
...  
Keyword(s):  
Coronary Flow ◽  
Flow Regulation ◽  
Coronary Flow Regulation

Effect of changes in blood CO2 level on coronary flow and myocardial O2 consumption

1960 ◽  
Vol 199 (2) ◽  
pp. 349-354 ◽  
Author(s):  
H. Feinberg ◽  
A. Gerola ◽  
L. N. Katz
Keyword(s):  
Oxygen Consumption ◽  
Coronary Flow ◽  
Myocardial Oxygen Consumption ◽  
Gas Mixture ◽  
Aortic Blood ◽  
Anesthetized Dogs ◽  
Myocardial O2 Consumption ◽  
Aortic Blood Pressure ◽  
Co2 Level ◽  
Oxygen Difference

The effect of hypo- and hypercapnia—induced by changing the respiratory gas mixture—on coronary flow and myocardial oxygen consumption was observed at constant cardiac output and over a broad range of pressure-loads in open-chested, anesthetized dogs. The correlation of cardiac effort (as indexed by the product of heart rate and mean aortic blood pressure) with myocardial oxygen consumption was not altered by increasing or decreasing the arterial CO2 content. Coronary blood flow was observed to be increased relative to the cardiac effort during hypercapnia but not during hypocapnia. The coronary arteriovenous oxygen difference and the percentage of oxygen extracted decreased during hypercapnia pari passu with the increase in venous oxygen content.

Effect of erythrocyte storage and oxyhemoglobin affinity changes on cardiac function

1985 ◽  
Vol 248 (4) ◽  
pp. H508-H515 ◽  
Author(s):  
C. S. Apstein ◽  
R. C. Dennis ◽  
L. Briggs ◽  
W. M. Vogel ◽  
J. Frazer ◽  
...  
Keyword(s):  
Oxygen Consumption ◽  
Coronary Flow ◽  
Myocardial Oxygen Consumption ◽  
Myocardial Function ◽  
Contractile Function ◽  
Storage Conditions ◽  
Tissue Oxygen ◽  
Biochemical Treatment ◽  
Stress States ◽  
Stored Blood

Storage of blood can depress erythrocyte 2,3-diphosphoglycerate (DPG) levels and thereby increase oxyhemoglobin affinity and potentially decrease capillary-to-tissue oxygen transport. We measured myocardial function and metabolism in isolated rabbit hearts with fixed coronary flow under basal conditions and during isoproterenol stress at 37 and 30 degrees C, comparing high and low oxyhemoglobin affinity (OHA) erythrocytes. The high OHA state resulted from standard storage conditions, which caused depressed values of DPG and P50 (the oxygen tension at which hemoglobin is 50% saturated). The low OHA erythrocytes were initially stored and then underwent biochemical treatment to restore the DPG and P50 values to normal. The low OHA cells released more oxygen, and myocardial oxygen consumption and contractile function were increased relative to the high OHA cells during both the basal and stress states at both 37 and 30 degrees C. These observations may be relevant for patients with limited coronary flow when such patients receive large transfusions of stored blood.

Assisted circulation. III. The effect of synchronized arterial counterpulsation on myocardial oxygen consumption and coronary flow

1962 ◽  
Vol 64 (6) ◽  
pp. 789-795 ◽  
Author(s):  
Armand A. Lefemine ◽  
Henry B.C. Low ◽  
Manfred L. Cohen ◽  
Steven Lunzer ◽  
Dwight E. Harken
Keyword(s):  
Oxygen Consumption ◽  
Coronary Flow ◽  
Myocardial Oxygen Consumption ◽  
Assisted Circulation

scholarly journals The rate-pressure product as an index of myocardial oxygen consumption during exercise in patients with angina pectoris.

Circulation ◽  
1978 ◽  
Vol 57 (3) ◽  
pp. 549-556 ◽  
Author(s):  
F L Gobel ◽  
L A Norstrom ◽  
R R Nelson ◽  
C R Jorgensen ◽  
Y Wang
Keyword(s):  
Oxygen Consumption ◽  
Angina Pectoris ◽  
Myocardial Oxygen Consumption ◽  
Rate Pressure Product
Sign in / Sign up

Export Citation Format

Share Document